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Entry version 144 (12 Aug 2020)
Sequence version 2 (21 Sep 2011)
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Protein

Uncharacterized transcriptional regulatory protein YLL054C

Gene

YLL054C

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Required for growth on non-fermentable carbon sources.1 Publication

Miscellaneous

Present with 339 molecules/cell in log phase SD medium.1 Publication

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section specifies the position and type of each DNA-binding domain present within the protein.<p><a href='/help/dna_bind' target='_top'>More...</a></p>DNA bindingi15 – 42Zn(2)-C6 fungal-typePROSITE-ProRule annotationAdd BLAST28

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-binding
Biological processTranscription, Transcription regulation
LigandMetal-binding, Zinc

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...
BioCyci
YEAST:G3O-32153-MONOMER

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Uncharacterized transcriptional regulatory protein YLL054C
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Ordered Locus Names:YLL054C
ORF Names:L0584
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri559292 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002311 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome XII

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
FungiDB:YLL054C

Saccharomyces Genome Database

More...
SGDi
S000003977, YLL054C

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002471351 – 843Uncharacterized transcriptional regulatory protein YLL054CAdd BLAST843

Proteomic databases

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q12244

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q12244

PRoteomics IDEntifications database

More...
PRIDEi
Q12244

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q12244

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
31261, 47 interactors

Database of interacting proteins

More...
DIPi
DIP-5612N

Protein interaction database and analysis system

More...
IntActi
Q12244, 1 interactor

STRING: functional protein association networks

More...
STRINGi
4932.YLL054C

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q12244, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q12244

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG502RJ72, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000176335

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_015392_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q12244

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00067, GAL4, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
4.10.240.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001138, Zn2-C6_fun-type_DNA-bd
IPR036864, Zn2-C6_fun-type_DNA-bd_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00172, Zn_clus, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00066, GAL4, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF57701, SSF57701, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00463, ZN2_CY6_FUNGAL_1, 1 hit
PS50048, ZN2_CY6_FUNGAL_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q12244-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSIASQKKVK PSFVCLRCKQ RKIKCDKLWP TCSKCKASSS ICSYEVEPGR
60 70 80 90 100
INKSPTIENA PHRDIRNITP ASMSASGSFT SILNPSTKDW EMKNFAMNLS
110 120 130 140 150
NAHDKLVVMN NTTIVDSPFA FHSILQHDLY AKALTTCIHE RILIDVERHR
160 170 180 190 200
ENVSANNKKR ELNLTIGDIG PLFFIDKAAL KFIENTSKTS KLYPPIDFLY
210 220 230 240 250
NTYDYEQAHP EENNDKISIN ILLEELSKYF LNKNEVDGLI VDFYKTIYPV
260 270 280 290 300
YPLLEISLFE DNIRELLQLN EFNGYNIVFA GKDSRRKLET ITLLTIILAF
310 320 330 340 350
SYRRLSLSTS HSFKESFGVK SNNLTLLAHK LLALMNVFQY VNEHTLCCLL
360 370 380 390 400
YFFILRYLNP DQADMYPTHS DILNLKFLEN VAIKLGLNEE PFQYTRYVSE
410 420 430 440 450
SDDYPRLFNL RRKLWLGVQF LKFGILIPEG DSDILSLEYL RSFMKTDESL
460 470 480 490 500
PELFERNYAS TNNLDLSLMA TAENIYHLHL SLQVLLTSCF PINGPSYLKE
510 520 530 540 550
VLDNIDKTKD FLNQKFPLIL SSLGEPRMKS LHINVPSSLA NEESFDFSTF
560 570 580 590 600
EENETFIANV ISYTCTMNIY DSLSLHFENQ CFKNALEYKT YYHRFTFTAI
610 620 630 640 650
QDYLTLLKLI SEYFNGSLLH LREPFGFATQ KVVRFSIHRL LIFQATLLVR
660 670 680 690 700
LFYKKDTCDR SSAAMGMLND RNGRLSRVIE KMIKLMSYHM KLLVEIVISK
710 720 730 740 750
LEKSYLGSFI SVSIFRYIIY LVDTDALSAF ISDYWKSDAV MDERYSRIHR
760 770 780 790 800
IVGLKWGMGR DKSFSFTSKL NNPQFLGSLD LEILEELEKL ISAQEFSRNF
810 820 830 840
TEDVDESLQS EIDLMNYDNE ALNQLMAIDL DKLLGIFPNL SNF
Length:843
Mass (Da):97,610
Last modified:September 21, 2011 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iF03F8237481BE260
GO

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAT92638 differs from that shown. Reason: Frameshift.Curated
The sequence CAA88003 differs from that shown. Reason: Frameshift.Curated
The sequence CAA97507 differs from that shown. Reason: Frameshift.Curated

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
Z47973 Genomic DNA Translation: CAA88003.1 Frameshift.
Z73159 Genomic DNA Translation: CAA97507.1 Frameshift.
AY692619 Genomic DNA Translation: AAT92638.1 Frameshift.
BK006945 Genomic DNA Translation: DAA09270.2

Protein sequence database of the Protein Information Resource

More...
PIRi
S50966

NCBI Reference Sequences

More...
RefSeqi
NP_013046.2, NM_001181874.2

Genome annotation databases

Ensembl fungal genome annotation project

More...
EnsemblFungii
YLL054C_mRNA; YLL054C; YLL054C

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
850672

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
sce:YLL054C

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z47973 Genomic DNA Translation: CAA88003.1 Frameshift.
Z73159 Genomic DNA Translation: CAA97507.1 Frameshift.
AY692619 Genomic DNA Translation: AAT92638.1 Frameshift.
BK006945 Genomic DNA Translation: DAA09270.2
PIRiS50966
RefSeqiNP_013046.2, NM_001181874.2

3D structure databases

SMRiQ12244
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi31261, 47 interactors
DIPiDIP-5612N
IntActiQ12244, 1 interactor
STRINGi4932.YLL054C

PTM databases

iPTMnetiQ12244

Proteomic databases

MaxQBiQ12244
PaxDbiQ12244
PRIDEiQ12244

Genome annotation databases

EnsemblFungiiYLL054C_mRNA; YLL054C; YLL054C
GeneIDi850672
KEGGisce:YLL054C

Organism-specific databases

EuPathDBiFungiDB:YLL054C
SGDiS000003977, YLL054C

Phylogenomic databases

eggNOGiENOG502RJ72, Eukaryota
GeneTreeiENSGT00940000176335
HOGENOMiCLU_015392_0_0_1
InParanoidiQ12244

Enzyme and pathway databases

BioCyciYEAST:G3O-32153-MONOMER

Miscellaneous databases

Protein Ontology

More...
PROi
PR:Q12244
RNActiQ12244, protein

Family and domain databases

CDDicd00067, GAL4, 1 hit
Gene3Di4.10.240.10, 1 hit
InterProiView protein in InterPro
IPR001138, Zn2-C6_fun-type_DNA-bd
IPR036864, Zn2-C6_fun-type_DNA-bd_sf
PfamiView protein in Pfam
PF00172, Zn_clus, 1 hit
SMARTiView protein in SMART
SM00066, GAL4, 1 hit
SUPFAMiSSF57701, SSF57701, 1 hit
PROSITEiView protein in PROSITE
PS00463, ZN2_CY6_FUNGAL_1, 1 hit
PS50048, ZN2_CY6_FUNGAL_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiYL054_YEAST
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q12244
Secondary accession number(s): D6VXV4
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 25, 2006
Last sequence update: September 21, 2011
Last modified: August 12, 2020
This is version 144 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  2. Yeast chromosome XII
    Yeast (Saccharomyces cerevisiae) chromosome XII: entries and gene names
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