Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

1-aminocyclopropane-1-carboxylate synthase 1

Gene

ACC1

Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Catalyzes the formation of 1-aminocyclopropane-1-carboxylate, a direct precursor of ethylene in higher plants.

Catalytic activityi

S-adenosyl-L-methionine = 1-aminocyclopropane-1-carboxylate + methylthioadenosine.

Cofactori

Pathwayi: ethylene biosynthesis via S-adenosyl-L-methionine

This protein is involved in step 1 of the subpathway that synthesizes ethylene from S-adenosyl-L-methionine.
Proteins known to be involved in the 2 steps of the subpathway in this organism are:
  1. 1-aminocyclopropane-1-carboxylate synthase 1 (ACC1)
  2. 1-aminocyclopropane-1-carboxylate oxidase 1 (ACO1)
This subpathway is part of the pathway ethylene biosynthesis via S-adenosyl-L-methionine, which is itself part of Alkene biosynthesis.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes ethylene from S-adenosyl-L-methionine, the pathway ethylene biosynthesis via S-adenosyl-L-methionine and in Alkene biosynthesis.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLyase
Biological processEthylene biosynthesis, Fruit ripening
LigandPyridoxal phosphate, S-adenosyl-L-methionine

Enzyme and pathway databases

BRENDAi4.4.1.14 4460
UniPathwayi
UPA00384;UER00562

Names & Taxonomyi

Protein namesi
Recommended name:
1-aminocyclopropane-1-carboxylate synthase 1 (EC:4.4.1.14)
Short name:
ACC synthase 1
Alternative name(s):
S-adenosyl-L-methionine methylthioadenosine-lyase 1
Gene namesi
Name:ACC1
Ordered Locus Names:Os03g0727600, LOC_Os03g51740
OrganismiOryza sativa subsp. japonica (Rice)
Taxonomic identifieri39947 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBOP cladeOryzoideaeOryzeaeOryzinaeOryzaOryza sativa
Proteomesi
  • UP000059680 Componenti: Chromosome 3

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001239161 – 4871-aminocyclopropane-1-carboxylate synthase 1Add BLAST487

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei286N6-(pyridoxal phosphate)lysineBy similarity1

Proteomic databases

PaxDbiQ10DK7

Expressioni

Gene expression databases

ExpressionAtlasiQ10DK7 differential
GenevisibleiQ10DK7 OS

Interactioni

Subunit structurei

Homodimer.

Protein-protein interaction databases

STRINGi39947.LOC_Os03g51740.1

Structurei

3D structure databases

ProteinModelPortaliQ10DK7
SMRiQ10DK7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG0256 Eukaryota
COG0436 LUCA
KOiK01762
OMAiPYYGAIT
OrthoDBiEOG093608EZ

Family and domain databases

Gene3Di3.40.640.10, 1 hit
3.90.1150.10, 2 hits
InterProiView protein in InterPro
IPR004839 Aminotransferase_I/II
IPR004838 NHTrfase_class1_PyrdxlP-BS
IPR015424 PyrdxlP-dep_Trfase
IPR015422 PyrdxlP-dep_Trfase_dom1
IPR015421 PyrdxlP-dep_Trfase_major
PfamiView protein in Pfam
PF00155 Aminotran_1_2, 1 hit
SUPFAMiSSF53383 SSF53383, 1 hit
PROSITEiView protein in PROSITE
PS00105 AA_TRANSFER_CLASS_1, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.iShow all

Q10DK7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MVSQVVAEEK PQLLSKKAGC NSHGQDSSYF LGWQEYEKNP FDPVSNPSGI
60 70 80 90 100
IQMGLAENQL SFDLLEEWLE KNPHALGLRR EGGGASVFRE LALFQDYHGL
110 120 130 140 150
PAFKNALARF MSEQRGYKVV FDPSNIVLTA GATSANEALM FCLADHGDAF
160 170 180 190 200
LIPTPYYPGF DRDLKWRTGA EIVPVHCASA NGFRVTRPAL DDAYRRAQKR
210 220 230 240 250
RLRVKGVLIT NPSNPLGTAS PRADLETIVD FVAAKGIHLI SDEIYAGTAF
260 270 280 290 300
AEPPAGFVSA LEVVAGRDGG GADVSDRVHV VYSLSKDLGL PGFRVGAIYS
310 320 330 340 350
ANAAVVSAAT KMSSFGLVSS QTQYLLAALL GDRDFTRSYV AENKRRIKER
360 370 380 390 400
HDQLVDGLRE IGIGCLPSNA GLFCWVDMSH LMRSRSFAGE MELWKKVVFE
410 420 430 440 450
VGLNISPGSS CHCREPGWFR VCFANMSAKT LDVAMQRLRS FVDSATGGGD
460 470 480
NAALRRAAVP VRSVSCPLAI KWALRLTPSI ADRKAER
Length:487
Mass (Da):53,139
Last modified:August 22, 2006 - v1
Checksum:i561D262125D7759E
GO

Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q8S6N5ACC1_ORYSJ
Acetyl-CoA carboxylase 1
ACC1 Os10g0363300, LOC_Os10g21910, OsJ_31236, OSJNBa0073L01.2
2,267Annotation score:
A0A0P0XT84A0A0P0XT84_ORYSJ
Os10g0363300 protein
Os10g0363300 OSNPB_100363300
244Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC135956 Genomic DNA Translation: AAT77071.1
DP000009 Genomic DNA Translation: ABF98659.1
AP008209 Genomic DNA Translation: BAF13056.1
AP014959 Genomic DNA Translation: BAS86187.1
AK071011 mRNA Translation: BAG92257.1
RefSeqiXP_015629245.1, XM_015773759.1
UniGeneiOs.53146

Genome annotation databases

EnsemblPlantsiOs03t0727600-01; Os03t0727600-01; Os03g0727600
GeneIDi4333976
GrameneiOs03t0727600-01; Os03t0727600-01; Os03g0727600
KEGGiosa:4333976

Similar proteinsi

Entry informationi

Entry namei1A11_ORYSJ
AccessioniPrimary (citable) accession number: Q10DK7
Secondary accession number(s): B7EIR0, Q07215, Q6ATI2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 12, 2007
Last sequence update: August 22, 2006
Last modified: May 23, 2018
This is version 83 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again