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Entry version 140 (08 May 2019)
Sequence version 2 (01 Nov 1997)
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Protein

DNA-directed RNA polymerase II subunit RPB2

Gene

rpb-2

Organism
Caenorhabditis elegans
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Second largest component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Proposed to contribute to the polymerase catalytic activity and forms the polymerase active center together with the largest subunit. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB2 is part of the core element with the central large cleft, the clamp element that moves to open and close the cleft and the jaws that are thought to grab the incoming DNA template (By similarity).By similarity

Miscellaneous

The binding of ribonucleoside triphosphate to the RNA polymerase II transcribing complex probably involves a two-step mechanism. The initial binding seems to occur at the entry (E) site and involves a magnesium ion coordinated by three conserved aspartate residues of the two largest RNA Pol II subunits (By similarity).By similarity

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Function’ section indicates at which position the protein binds a given metal ion. The nature of the metal is indicated in the ‘Description’ field.<p><a href='/help/metal' target='_top'>More...</a></p>Metal bindingi798Magnesium; shared with RPB1By similarity1
Metal bindingi1125ZincBy similarity1
Metal bindingi1128ZincBy similarity1
Metal bindingi1143ZincBy similarity1
Metal bindingi1146ZincBy similarity1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Function’ section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri1125 – 1146C4-typeAdd BLAST22

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionNucleotidyltransferase, Transferase
Biological processTranscription
LigandMagnesium, Metal-binding, Zinc

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-CEL-112382 Formation of RNA Pol II elongation complex
R-CEL-113418 Formation of the Early Elongation Complex
R-CEL-5578749 Transcriptional regulation by small RNAs
R-CEL-674695 RNA Polymerase II Pre-transcription Events
R-CEL-6781823 Formation of TC-NER Pre-Incision Complex
R-CEL-6782135 Dual incision in TC-NER
R-CEL-6782210 Gap-filling DNA repair synthesis and ligation in TC-NER
R-CEL-6796648 TP53 Regulates Transcription of DNA Repair Genes
R-CEL-6803529 FGFR2 alternative splicing
R-CEL-6807505 RNA polymerase II transcribes snRNA genes
R-CEL-72086 mRNA Capping
R-CEL-72163 mRNA Splicing - Major Pathway
R-CEL-72165 mRNA Splicing - Minor Pathway
R-CEL-73776 RNA Polymerase II Promoter Escape
R-CEL-73779 RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
R-CEL-75953 RNA Polymerase II Transcription Initiation
R-CEL-75955 RNA Polymerase II Transcription Elongation
R-CEL-76042 RNA Polymerase II Transcription Initiation And Promoter Clearance
R-CEL-77075 RNA Pol II CTD phosphorylation and interaction with CE
R-CEL-9018519 Estrogen-dependent gene expression

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
DNA-directed RNA polymerase II subunit RPB2 (EC:2.7.7.6)
Short name:
RNA polymerase II subunit 2
Short name:
RNA polymerase II subunit B2
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:rpb-2
ORF Names:C26E6.4
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiCaenorhabditis elegans
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri6239 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditinaRhabditomorphaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001940 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome III

Organism-specific databases

WormBase

More...
WormBasei
C26E6.4 ; CE52920 ; WBGene00016140 ; rpb-2

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

DNA-directed RNA polymerase, Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000480831 – 1193DNA-directed RNA polymerase II subunit RPB2Add BLAST1193

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q10578

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q10578

PeptideAtlas

More...
PeptideAtlasi
Q10578

PRoteomics IDEntifications database

More...
PRIDEi
Q10578

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q10578

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
WBGene00016140 Expressed in 5 organ(s), highest expression level in multi-cellular organism

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Component of the RNA polymerase II (Pol II) complex consisting of 12 subunits.By similarity

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

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BioGridi
40901, 4 interactors

STRING: functional protein association networks

More...
STRINGi
6239.C26E6.4

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

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SMRi
Q10578

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the RNA polymerase beta chain family.Curated

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri1125 – 1146C4-typeAdd BLAST22

Keywords - Domaini

Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0214 Eukaryota
COG0085 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00950000183132

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000222962

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q10578

KEGG Orthology (KO)

More...
KOi
K03010

Identification of Orthologs from Complete Genome Data

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OMAi
QIFLGPT

Database of Orthologous Groups

More...
OrthoDBi
42570at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q10578

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00653 RNA_pol_B_RPB2, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.40.270.10, 1 hit
2.40.50.150, 1 hit
3.90.1110.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR015712 DNA-dir_RNA_pol_su2
IPR007120 DNA-dir_RNAP_su2_dom
IPR037033 DNA-dir_RNAP_su2_hyb_sf
IPR007121 RNA_pol_bsu_CS
IPR007644 RNA_pol_bsu_protrusion
IPR007642 RNA_pol_Rpb2_2
IPR037034 RNA_pol_Rpb2_2_sf
IPR007645 RNA_pol_Rpb2_3
IPR007646 RNA_pol_Rpb2_4
IPR007647 RNA_pol_Rpb2_5
IPR007641 RNA_pol_Rpb2_7
IPR014724 RNA_pol_RPB2_OB-fold

The PANTHER Classification System

More...
PANTHERi
PTHR20856 PTHR20856, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF04563 RNA_pol_Rpb2_1, 1 hit
PF04561 RNA_pol_Rpb2_2, 1 hit
PF04565 RNA_pol_Rpb2_3, 1 hit
PF04566 RNA_pol_Rpb2_4, 1 hit
PF04567 RNA_pol_Rpb2_5, 1 hit
PF00562 RNA_pol_Rpb2_6, 1 hit
PF04560 RNA_pol_Rpb2_7, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS01166 RNA_POL_BETA, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q10578-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MYDDEDEMVN DPMDGDYIDD SDEISAEAWQ EACWVVISAY FDEKGLVRQQ
60 70 80 90 100
LDSFDEFVQM NVQRIVEDSP PVELQSENQH LGTDMENPAK FSLKFNQIYL
110 120 130 140 150
SKPTHWEKDG APMPMMPNEA RLRNLTYASP LYVDITKVVT RDDSATEKVY
160 170 180 190 200
DKVFVGKVPV MLRSSYCMLS NMTDRDLTEL NECPLDPGGY FVINGSEKVL
210 220 230 240 250
IAQEKMATNT VYVFSMKDGK YAFKTECRSC LENSSRPTST MWVNMLARGG
260 270 280 290 300
GGGKKTAMGQ RIIGILPYIK QEIPIMIVFR ALGFVSDRDI LGHIIYDFND
310 320 330 340 350
PEMMEMVKPS LDEAFVIQEQ NVALNFIGAR GAKPGVTREQ RIKYAREILQ
360 370 380 390 400
KELLPHVGVS EHCETKKAFF IGYMVHRLLL AALGRRELDD RDHIGNKRLD
410 420 430 440 450
LAGPLLAFLF RSLFRNLLKE MRMTAQKYIN KNDDFALDVC VKTSTITRGL
460 470 480 490 500
TYSLATGNWG DQKKAHQSRA GVSQVLNRLT YTATLSHLRR ANSPIGREGK
510 520 530 540 550
LAKPRQLHNT QWGMVCPAET PEGQAVGLVK NLALMAYISV GSLPEPILEF
560 570 580 590 600
LEEWSMENLE EVSPSAIADA TKIFVNGAWV GIHREPDQLM TTLKKLRRQM
610 620 630 640 650
DIIVSEVSMV RDIRDREIRI YTDAGRVCRP LLIVENQKLA LKKRHIDQLK
660 670 680 690 700
EAADEANKYT WSDLVGGGVV ELIDSMEEET SMIAMMPEDL RSGGYCDTHT
710 720 730 740 750
HCEIHPAMIL GVCASIIPFP DHNQSPRNTY QSAMGKQAMG VYTTNFHVRM
760 770 780 790 800
DTLAHVLYYP QKPLVTTRSM EYLRFNELPA GINAIVAILS YSGYNQEDSV
810 820 830 840 850
IMNNSAIDRG LFRSVFYRSY RDNEANLDNA NEELIEKPTR EKCSGMRHSL
860 870 880 890 900
YDKLDEDGII SPGMRVSGDD VIIGKTVALP DIDDDLDASG KKYPKRDAST
910 920 930 940 950
FLRSSETGIV DQVMLSLNSD GNKFVKIRMR SVRLPQIGDK FASRHGQKGT
960 970 980 990 1000
MGIMYRQEDM PFTAEGLTPD IIINPHAVPS RMTIGHLIEC LQGKLSANKG
1010 1020 1030 1040 1050
EIGDATPFND TVNVQKISGL LCEYGYHLRG NEVMYNGHTG KKLTTQIFFG
1060 1070 1080 1090 1100
PTYYQRLKHM VDDKIHSRAR GPIQMMNRQP MEGRARDGGL RFGEMERDCQ
1110 1120 1130 1140 1150
ISHGATQFLR ERLFEVSDPY HVYVCNNCGL IVVANLRTNS FECKACRNKT
1160 1170 1180 1190
QVSAVRIPYA CKLLFQELMS MSIAPRLMVK PRQSKRSKHQ SEA
Length:1,193
Mass (Da):134,905
Last modified:November 1, 1997 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iB8A85E74E9CC7EBE
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
FO080680 Genomic DNA Translation: CCD65728.1
U10333 mRNA Translation: AAA50224.1

Protein sequence database of the Protein Information Resource

More...
PIRi
E88445
T43701

NCBI Reference Sequences

More...
RefSeqi
NP_498047.1, NM_065646.4

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
C26E6.4; C26E6.4; WBGene00016140

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
175668

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
cel:CELE_C26E6.4

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FO080680 Genomic DNA Translation: CCD65728.1
U10333 mRNA Translation: AAA50224.1
PIRiE88445
T43701
RefSeqiNP_498047.1, NM_065646.4

3D structure databases

SMRiQ10578
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi40901, 4 interactors
STRINGi6239.C26E6.4

PTM databases

iPTMnetiQ10578

Proteomic databases

EPDiQ10578
PaxDbiQ10578
PeptideAtlasiQ10578
PRIDEiQ10578

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiC26E6.4; C26E6.4; WBGene00016140
GeneIDi175668
KEGGicel:CELE_C26E6.4

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
175668
WormBaseiC26E6.4 ; CE52920 ; WBGene00016140 ; rpb-2

Phylogenomic databases

eggNOGiKOG0214 Eukaryota
COG0085 LUCA
GeneTreeiENSGT00950000183132
HOGENOMiHOG000222962
InParanoidiQ10578
KOiK03010
OMAiQIFLGPT
OrthoDBi42570at2759
PhylomeDBiQ10578

Enzyme and pathway databases

ReactomeiR-CEL-112382 Formation of RNA Pol II elongation complex
R-CEL-113418 Formation of the Early Elongation Complex
R-CEL-5578749 Transcriptional regulation by small RNAs
R-CEL-674695 RNA Polymerase II Pre-transcription Events
R-CEL-6781823 Formation of TC-NER Pre-Incision Complex
R-CEL-6782135 Dual incision in TC-NER
R-CEL-6782210 Gap-filling DNA repair synthesis and ligation in TC-NER
R-CEL-6796648 TP53 Regulates Transcription of DNA Repair Genes
R-CEL-6803529 FGFR2 alternative splicing
R-CEL-6807505 RNA polymerase II transcribes snRNA genes
R-CEL-72086 mRNA Capping
R-CEL-72163 mRNA Splicing - Major Pathway
R-CEL-72165 mRNA Splicing - Minor Pathway
R-CEL-73776 RNA Polymerase II Promoter Escape
R-CEL-73779 RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
R-CEL-75953 RNA Polymerase II Transcription Initiation
R-CEL-75955 RNA Polymerase II Transcription Elongation
R-CEL-76042 RNA Polymerase II Transcription Initiation And Promoter Clearance
R-CEL-77075 RNA Pol II CTD phosphorylation and interaction with CE
R-CEL-9018519 Estrogen-dependent gene expression

Miscellaneous databases

Protein Ontology

More...
PROi
PR:Q10578

Gene expression databases

BgeeiWBGene00016140 Expressed in 5 organ(s), highest expression level in multi-cellular organism

Family and domain databases

CDDicd00653 RNA_pol_B_RPB2, 1 hit
Gene3Di2.40.270.10, 1 hit
2.40.50.150, 1 hit
3.90.1110.10, 1 hit
InterProiView protein in InterPro
IPR015712 DNA-dir_RNA_pol_su2
IPR007120 DNA-dir_RNAP_su2_dom
IPR037033 DNA-dir_RNAP_su2_hyb_sf
IPR007121 RNA_pol_bsu_CS
IPR007644 RNA_pol_bsu_protrusion
IPR007642 RNA_pol_Rpb2_2
IPR037034 RNA_pol_Rpb2_2_sf
IPR007645 RNA_pol_Rpb2_3
IPR007646 RNA_pol_Rpb2_4
IPR007647 RNA_pol_Rpb2_5
IPR007641 RNA_pol_Rpb2_7
IPR014724 RNA_pol_RPB2_OB-fold
PANTHERiPTHR20856 PTHR20856, 1 hit
PfamiView protein in Pfam
PF04563 RNA_pol_Rpb2_1, 1 hit
PF04561 RNA_pol_Rpb2_2, 1 hit
PF04565 RNA_pol_Rpb2_3, 1 hit
PF04566 RNA_pol_Rpb2_4, 1 hit
PF04567 RNA_pol_Rpb2_5, 1 hit
PF00562 RNA_pol_Rpb2_6, 1 hit
PF04560 RNA_pol_Rpb2_7, 1 hit
PROSITEiView protein in PROSITE
PS01166 RNA_POL_BETA, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiRPB2_CAEEL
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q10578
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: November 1, 1997
Last modified: May 8, 2019
This is version 140 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Caenorhabditis elegans
    Caenorhabditis elegans: entries, gene names and cross-references to WormBase
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