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Protein

Transcriptional activator MN1

Gene

MN1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Transcriptional activator which specifically regulates expression of TBX22 in the posterior region of the developing palate. Required during later stages of palate development for growth and medial fusion of the palatal shelves. Promotes maturation and normal function of calvarial osteoblasts, including expression of the osteoclastogenic cytokine TNFSF11/RANKL. Necessary for normal development of the membranous bones of the skull (By similarity). May play a role in tumor suppression (Probable).By similarity1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionActivator, Developmental protein
Biological processTranscription, Transcription regulation

Enzyme and pathway databases

SIGNOR Signaling Network Open Resource

More...
SIGNORi
Q10571

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Transcriptional activator MN1Curated
Alternative name(s):
Probable tumor suppressor protein MN1Curated
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:MN1
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 22

Organism-specific databases

Eukaryotic Pathogen Database Resources

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EuPathDBi
HostDB:ENSG00000169184.5

Human Gene Nomenclature Database

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HGNCi
HGNC:7180 MN1

Online Mendelian Inheritance in Man (OMIM)

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MIMi
156100 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q10571

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the ‘Pathology and Biotech’ section provides information on the disease(s) associated with genetic variations in a given protein. The information is extracted from the scientific literature and diseases that are also described in the <a href="http://www.ncbi.nlm.nih.gov/sites/entrez?db=omim">OMIM</a> database are represented with a <a href="http://www.uniprot.org/diseases">controlled vocabulary</a> in the following way:<p><a href='/help/involvement_in_disease' target='_top'>More...</a></p>Involvement in diseasei

A chromosomal aberration involving MN1 may be a cause of acute myeloid leukemia (AML). Translocation t(12;22)(p13;q11) with ETV6.1 Publication
Defects in MN1 involved in the development of meningiomas, slowly growing benign tumors derived from the arachnoidal cap cells of the leptomeninges, the soft coverings of the brain and spinal cord. Meningiomas are believed to be the most common primary tumors of the central nervous system in man.1 Publication

Keywords - Diseasei

Tumor suppressor

Organism-specific databases

DisGeNET

More...
DisGeNETi
4330

MalaCards human disease database

More...
MalaCardsi
MN1
MIMi607174 phenotype

Open Targets

More...
OpenTargetsi
ENSG00000169184

Orphanet; a database dedicated to information on rare diseases and orphan drugs

More...
Orphaneti
263662 Familial multiple meningioma

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA30893

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
MN1

Domain mapping of disease mutations (DMDM)

More...
DMDMi
215274133

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000965211 – 1320Transcriptional activator MN1Add BLAST1320

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei1N-acetylmethionineCombined sources1
Modified residuei950PhosphoserineCombined sources1
Modified residuei954PhosphoserineCombined sources1
Modified residuei1007PhosphoserineCombined sources1
Modified residuei1081PhosphoserineCombined sources1

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

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EPDi
Q10571

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q10571

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q10571

PeptideAtlas

More...
PeptideAtlasi
Q10571

PRoteomics IDEntifications database

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PRIDEi
Q10571

ProteomicsDB human proteome resource

More...
ProteomicsDBi
58861

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q10571

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q10571

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Ubiquitously expressed. Highest levels in skeletal muscle.

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000169184 Expressed in 204 organ(s), highest expression level in cerebral cortex

CleanEx database of gene expression profiles

More...
CleanExi
HS_MN1

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q10571 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

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Genevisiblei
Q10571 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA003072

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
110473, 4 interactors

Protein interaction database and analysis system

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IntActi
Q10571, 1 interactor

Molecular INTeraction database

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MINTi
Q10571

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000304956

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

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ProteinModelPortali
Q10571

Database of comparative protein structure models

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ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi42 – 144Gly/His-richPROSITE-ProRule annotationAdd BLAST103
Compositional biasi336 – 517Pro-richPROSITE-ProRule annotationAdd BLAST182
Compositional biasi523 – 552Poly-GlnSequence analysisAdd BLAST30
Compositional biasi635 – 767Pro-richPROSITE-ProRule annotationAdd BLAST133

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IEWX Eukaryota
ENOG410YZ22 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000001777

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG106874

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q10571

KEGG Orthology (KO)

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KOi
K22543

Identification of Orthologs from Complete Genome Data

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OMAi
ASWNGSM

Database of Orthologous Groups

More...
OrthoDBi
EOG091G01PB

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q10571

TreeFam database of animal gene trees

More...
TreeFami
TF331780

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR037644 MN1

The PANTHER Classification System

More...
PANTHERi
PTHR15821 PTHR15821, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q10571-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MFGLDQFEPQ VNSRNAGQGE RNFNETGLSM NTHFKAPAFH TGGPPGPVDP
60 70 80 90 100
AMSALGEPPI LGMNMEPYGF HARGHSELHA GGLQAQPVHG FFGGQQPHHG
110 120 130 140 150
HPGSHHPHQH HPHFGGNFGG PDPGASCLHG GRLLGYGGAA GGLGSQPPFA
160 170 180 190 200
EGYEHMAESQ GPESFGPQRP GNLPDFHSSG ASSHAVPAPC LPLDQSPNRA
210 220 230 240 250
ASFHGLPSSS GSDSHSLEPR RVTNQGAVDS LEYNYPGEAP SGHFDMFSPS
260 270 280 290 300
DSEGQLPHYA AGRQVPGGAF PGASAMPRAA GMVGLSKMHA QPPQQQPQQQ
310 320 330 340 350
QQPQQQQQQH GVFFERFSGA RKMPVGLEPS VGSRHPLMQP PQQAPPPPQQ
360 370 380 390 400
QPPQQPPQQQ PPPPPGLLVR QNSCPPALPR PQQGEAGTPS GGLQDGGPML
410 420 430 440 450
PSQHAQFEYP IHRLENRSMH PYSEPVFSMQ HPPPQQAPNQ RLQHFDAPPY
460 470 480 490 500
MNVAKRPRFD FPGSAGVDRC ASWNGSMHNG ALDNHLSPSA YPGLPGEFTP
510 520 530 540 550
PVPDSFPSGP PLQHPAPDHQ SLQQQQQQQQ QQQQQQQQQQ QQQQQQQQQQ
560 570 580 590 600
RQNAALMIKQ MASRNQQQRL RQPNLAQLGH PGDVGQGGLV HGGPVGGLAQ
610 620 630 640 650
PNFEREGGST GAGRLGTFEQ QAPHLAQESA WFSGPHPPPG DLLPRRMGGS
660 670 680 690 700
GLPADCGPHD PSLAPPPPPG GSGVLFRGPL QEPMRMPGEG HVPALPSPGL
710 720 730 740 750
QFGGSLGGLG QLQSPGAGVG LPSAASERRP PPPDFATSAL GGQPGFPFGA
760 770 780 790 800
AGRQSTPHSG PGVNSPPSAG GGGGSSGGGG GGGAYPPQPD FQPSQRTSAS
810 820 830 840 850
KLGALSLGSF NKPSSKDNLF GQSCLAALST ACQNMIASLG APNLNVTFNK
860 870 880 890 900
KNPPEGKRKL SQNETDGAAV AGNPGSDYFP GGTAPGAPGP GGPSGTSSSG
910 920 930 940 950
SKASGPPNPP AQGDGTSLSP NYTLESTSGN DGKPVSGGGG RGRGRRKRDS
960 970 980 990 1000
GHVSPGTFFD KYSAAPDSGG APGVSPGQQQ ASGAAVGGSS AGETRGAPTP
1010 1020 1030 1040 1050
HEKALTSPSW GKGAELLLGD QPDLIGSLDG GAKSDSSSPN VGEFASDEVS
1060 1070 1080 1090 1100
TSYANEDEVS SSSDNPQALV KASRSPLVTG SPKLPPRGVG AGEHGPKAPP
1110 1120 1130 1140 1150
PALGLGIMSN STSTPDSYGG GGGPGHPGTP GLEQVRTPTS SSGAPPPDEI
1160 1170 1180 1190 1200
HPLEILQAQI QLQRQQFSIS EDQPLGLKGG KKGECAVGAS GAQNGDSELG
1210 1220 1230 1240 1250
SCCSEAVKSA MSTIDLDSLM AEHSAAWYMP ADKALVDSAD DDKTLAPWEK
1260 1270 1280 1290 1300
AKPQNPNSKE AHDLPANKAS ASQPGSHLQC LSVHCTDDVG DAKARASVPT
1310 1320
WRSLHSDISN RFGTFVAALT
Length:1,320
Mass (Da):136,001
Last modified:November 25, 2008 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i41CFFE16E5688B1C
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
H7C105H7C105_HUMAN
Transcriptional activator MN1
MN1
105Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_047533382Q → H. Corresponds to variant dbSNP:rs45589338Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
X82209 mRNA Translation: CAA57693.2
AL031591 Genomic DNA No translation available.
FO393416 Genomic DNA No translation available.
CH471095 Genomic DNA Translation: EAW59741.1
Z70218 mRNA Translation: CAA94179.1

The Consensus CDS (CCDS) project

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CCDSi
CCDS42998.1

NCBI Reference Sequences

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RefSeqi
NP_002421.3, NM_002430.2

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Hs.268515

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000302326; ENSP00000304956; ENSG00000169184

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
4330

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:4330

UCSC genome browser

More...
UCSCi
uc003adj.3 human

Keywords - Coding sequence diversityi

Chromosomal rearrangement, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

<p>This subsection of the <a href="http://www.uniprot.org/manual/cross_references_section">Cross-references</a> section provides links to various web resources that are relevant for a specific protein.<p><a href='/help/web_resource' target='_top'>More...</a></p>Web resourcesi

Atlas of Genetics and Cytogenetics in Oncology and Haematology

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X82209 mRNA Translation: CAA57693.2
AL031591 Genomic DNA No translation available.
FO393416 Genomic DNA No translation available.
CH471095 Genomic DNA Translation: EAW59741.1
Z70218 mRNA Translation: CAA94179.1
CCDSiCCDS42998.1
RefSeqiNP_002421.3, NM_002430.2
UniGeneiHs.268515

3D structure databases

ProteinModelPortaliQ10571
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi110473, 4 interactors
IntActiQ10571, 1 interactor
MINTiQ10571
STRINGi9606.ENSP00000304956

PTM databases

iPTMnetiQ10571
PhosphoSitePlusiQ10571

Polymorphism and mutation databases

BioMutaiMN1
DMDMi215274133

Proteomic databases

EPDiQ10571
MaxQBiQ10571
PaxDbiQ10571
PeptideAtlasiQ10571
PRIDEiQ10571
ProteomicsDBi58861

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
4330
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000302326; ENSP00000304956; ENSG00000169184
GeneIDi4330
KEGGihsa:4330
UCSCiuc003adj.3 human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
4330
DisGeNETi4330
EuPathDBiHostDB:ENSG00000169184.5

GeneCards: human genes, protein and diseases

More...
GeneCardsi
MN1
HGNCiHGNC:7180 MN1
HPAiHPA003072
MalaCardsiMN1
MIMi156100 gene
607174 phenotype
neXtProtiNX_Q10571
OpenTargetsiENSG00000169184
Orphaneti263662 Familial multiple meningioma
PharmGKBiPA30893

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG410IEWX Eukaryota
ENOG410YZ22 LUCA
GeneTreeiENSGT00390000001777
HOVERGENiHBG106874
InParanoidiQ10571
KOiK22543
OMAiASWNGSM
OrthoDBiEOG091G01PB
PhylomeDBiQ10571
TreeFamiTF331780

Enzyme and pathway databases

SIGNORiQ10571

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
MN1 human

The Gene Wiki collection of pages on human genes and proteins

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GeneWikii
MN1_(gene)

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
4330

Protein Ontology

More...
PROi
PR:Q10571

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000169184 Expressed in 204 organ(s), highest expression level in cerebral cortex
CleanExiHS_MN1
ExpressionAtlasiQ10571 baseline and differential
GenevisibleiQ10571 HS

Family and domain databases

InterProiView protein in InterPro
IPR037644 MN1
PANTHERiPTHR15821 PTHR15821, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiMN1_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q10571
Secondary accession number(s): A9Z1V9
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: November 25, 2008
Last modified: November 7, 2018
This is version 140 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 22
    Human chromosome 22: entries, gene names and cross-references to MIM
  2. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  3. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
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