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UniProtKB - Q10418 (MESD_LEUME)
Protein
Mesentericin-Y105 transport/processing ATP-binding protein MesD
Gene
mesD
Organism
Leuconostoc mesenteroides
Status
Functioni
Involved in the export process of the bacteriocin mesentericin-Y105.
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Active sitei | 22 | PROSITE-ProRule annotation | 1 |
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Nucleotide bindingi | 522 – 529 | ATPPROSITE-ProRule annotation | 8 |
GO - Molecular functioni
- ABC-type bacteriocin transporter activity Source: InterPro
- ATP binding Source: UniProtKB-KW
- cysteine-type peptidase activity Source: UniProtKB-KW
GO - Biological processi
- protein transport Source: UniProtKB-KW
Keywordsi
Molecular function | Hydrolase, Protease, Thiol protease, Translocase |
Biological process | Bacteriocin transport, Protein transport, Transport |
Ligand | ATP-binding, Nucleotide-binding |
Protein family/group databases
MEROPSi | C39.001 |
TCDBi | 3.A.1.112.8, the atp-binding cassette (abc) superfamily |
Names & Taxonomyi
Protein namesi | |
Gene namesi | Name:mesD |
Encoded oni | Plasmid pHY30 |
Organismi | Leuconostoc mesenteroides |
Taxonomic identifieri | 1245 [NCBI] |
Taxonomic lineagei | Bacteria › Firmicutes › Bacilli › Lactobacillales › Lactobacillaceae › Leuconostoc |
Subcellular locationi
Plasma membrane
Plasma Membrane
- plasma membrane Source: UniProtKB-SubCell
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 171 – 191 | HelicalPROSITE-ProRule annotationAdd BLAST | 21 | |
Transmembranei | 210 – 230 | HelicalPROSITE-ProRule annotationAdd BLAST | 21 | |
Transmembranei | 242 – 262 | HelicalPROSITE-ProRule annotationAdd BLAST | 21 | |
Transmembranei | 287 – 307 | HelicalPROSITE-ProRule annotationAdd BLAST | 21 | |
Transmembranei | 311 – 331 | HelicalPROSITE-ProRule annotationAdd BLAST | 21 | |
Transmembranei | 401 – 421 | HelicalPROSITE-ProRule annotationAdd BLAST | 21 | |
Transmembranei | 429 – 449 | HelicalPROSITE-ProRule annotationAdd BLAST | 21 | |
Transmembranei | 518 – 538 | HelicalPROSITE-ProRule annotationAdd BLAST | 21 |
Keywords - Cellular componenti
Cell membrane, MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000092502 | 1 – 722 | Mesentericin-Y105 transport/processing ATP-binding protein MesDAdd BLAST | 722 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 16 – 143 | Peptidase C39PROSITE-ProRule annotationAdd BLAST | 128 | |
Domaini | 173 – 455 | ABC transmembrane type-1PROSITE-ProRule annotationAdd BLAST | 283 | |
Domaini | 489 – 722 | ABC transporterPROSITE-ProRule annotationAdd BLAST | 234 |
Sequence similaritiesi
Belongs to the ABC transporter superfamily.Curated
Keywords - Domaini
Transmembrane, Transmembrane helixFamily and domain databases
Gene3Di | 1.20.1560.10, 1 hit 3.40.50.300, 1 hit |
InterProi | View protein in InterPro IPR003593, AAA+_ATPase IPR011527, ABC1_TM_dom IPR036640, ABC1_TM_sf IPR003439, ABC_transporter-like_ATP-bd IPR017871, ABC_transporter-like_CS IPR027417, P-loop_NTPase IPR005897, Pept_C39_ABC_bacteriocin IPR005074, Peptidase_C39 IPR039421, Type_1_exporter |
PANTHERi | PTHR24221, PTHR24221, 1 hit |
Pfami | View protein in Pfam PF00664, ABC_membrane, 1 hit PF00005, ABC_tran, 1 hit PF03412, Peptidase_C39, 1 hit |
SMARTi | View protein in SMART SM00382, AAA, 1 hit |
SUPFAMi | SSF52540, SSF52540, 1 hit SSF90123, SSF90123, 1 hit |
TIGRFAMsi | TIGR01193, bacteriocin_ABC, 1 hit |
PROSITEi | View protein in PROSITE PS50929, ABC_TM1F, 1 hit PS00211, ABC_TRANSPORTER_1, 1 hit PS50893, ABC_TRANSPORTER_2, 1 hit PS50990, PEPTIDASE_C39, 1 hit |
i Sequence
Sequence statusi: Complete.
Q10418-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MVKTPMFHKK IDYISQVDER DCGVAALAMI LAHYKTRLSL AKLRDLAKTD
60 70 80 90 100
MEGTTALGIV KAANALDFET MPIQADLSLF DKKDLPYPFI AHVIKEGKYP
110 120 130 140 150
HYYVVYGMKG DQLLIADPDN TVGKTKMTKA HFNEEWTGVS IFIAPNPTYK
160 170 180 190 200
PTKEKKRSLT SFIPVITRQK LLVINIVIAA LLVTLVSILG SYYLQGIIDT
210 220 230 240 250
YIPNNMKNTL GIVSLGLIFA YVIQQLLSYA RDYLLIVMGQ RLSIDIILSY
260 270 280 290 300
IKHIFELPMS FFATRRTGEI VSRFTDANAI IEALASTMLS VFLDLGILVI
310 320 330 340 350
VGTVLVVQNS TLFLISLIAI PAYALVVWLF MRPFSKMNND QMQAGSMLSS
360 370 380 390 400
SIIEDINGVE TIKALNSEAT AYHKIDHEFV TYLEKSFVYA KTEAVQNAIK
410 420 430 440 450
SLLQLSLNVV ILWVGAQLVM TNKISVGQLI TYNALLGFFT DPLQNIINLQ
460 470 480 490 500
TKLQQASVAN NRLNEVYLVD SEFKDSHQMT EKITPNSSLV ADHITYKYGF
510 520 530 540 550
GAPAIDDVSL TITAGEKIAL VGISGSGKST LVKLLVNFFQ PESGTISLGP
560 570 580 590 600
TPLANLDKHE LRGHINYLPQ EPFIFSGSIM ENLLLGAKPG TTQEDIIRAV
610 620 630 640 650
EIAEIKDDIE KMSQGFGTEL AESGNISGGQ KQRIALARAI LVDSPVLILD
660 670 680 690 700
ESTSNLDVLT EKKIIDNLMK LTEKTIIFVA HRLTISQRVD RILTMQSGKI
710 720
IEDGTHDTLL KAGGFYASLF NH
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | X81803 Genomic DNA Translation: CAA57402.1 |
PIRi | S52205 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | X81803 Genomic DNA Translation: CAA57402.1 |
PIRi | S52205 |
3D structure databases
AlphaFoldDBi | Q10418 |
SMRi | Q10418 |
ModBasei | Search... |
Protein family/group databases
MEROPSi | C39.001 |
TCDBi | 3.A.1.112.8, the atp-binding cassette (abc) superfamily |
Family and domain databases
Gene3Di | 1.20.1560.10, 1 hit 3.40.50.300, 1 hit |
InterProi | View protein in InterPro IPR003593, AAA+_ATPase IPR011527, ABC1_TM_dom IPR036640, ABC1_TM_sf IPR003439, ABC_transporter-like_ATP-bd IPR017871, ABC_transporter-like_CS IPR027417, P-loop_NTPase IPR005897, Pept_C39_ABC_bacteriocin IPR005074, Peptidase_C39 IPR039421, Type_1_exporter |
PANTHERi | PTHR24221, PTHR24221, 1 hit |
Pfami | View protein in Pfam PF00664, ABC_membrane, 1 hit PF00005, ABC_tran, 1 hit PF03412, Peptidase_C39, 1 hit |
SMARTi | View protein in SMART SM00382, AAA, 1 hit |
SUPFAMi | SSF52540, SSF52540, 1 hit SSF90123, SSF90123, 1 hit |
TIGRFAMsi | TIGR01193, bacteriocin_ABC, 1 hit |
PROSITEi | View protein in PROSITE PS50929, ABC_TM1F, 1 hit PS00211, ABC_TRANSPORTER_1, 1 hit PS50893, ABC_TRANSPORTER_2, 1 hit PS50990, PEPTIDASE_C39, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | MESD_LEUME | |
Accessioni | Q10418Primary (citable) accession number: Q10418 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | October 1, 1996 |
Last sequence update: | October 1, 1996 | |
Last modified: | May 25, 2022 | |
This is version 117 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
PlasmidDocuments
- SIMILARITY comments
Index of protein domains and families