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Protein

Putative phospholipid-transporting ATPase C6C3.06c

Gene

SPAC6C3.06c

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + H2O + phospholipid(Side 1) = ADP + phosphate + phospholipid(Side 2).

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei4084-aspartylphosphate intermediateBy similarity1
Metal bindingi770MagnesiumBy similarity1
Metal bindingi774MagnesiumBy similarity1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase
LigandATP-binding, Magnesium, Metal-binding, Nucleotide-binding

Enzyme and pathway databases

ReactomeiR-SPO-936837 Ion transport by P-type ATPases

Names & Taxonomyi

Protein namesi
Recommended name:
Putative phospholipid-transporting ATPase C6C3.06c (EC:3.6.3.1)
Gene namesi
ORF Names:SPAC6C3.06c
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome I

Organism-specific databases

EuPathDBiFungiDB:SPAC6C3.06c
PomBaseiSPAC6C3.06c

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei133 – 153HelicalSequence analysisAdd BLAST21
Transmembranei274 – 294HelicalSequence analysisAdd BLAST21
Transmembranei317 – 337HelicalSequence analysisAdd BLAST21
Transmembranei344 – 364HelicalSequence analysisAdd BLAST21
Transmembranei768 – 788HelicalSequence analysisAdd BLAST21
Transmembranei843 – 863HelicalSequence analysisAdd BLAST21
Transmembranei913 – 933HelicalSequence analysisAdd BLAST21
Transmembranei939 – 959HelicalSequence analysisAdd BLAST21
Transmembranei965 – 985HelicalSequence analysisAdd BLAST21
Transmembranei992 – 1012HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000463191 – 1033Putative phospholipid-transporting ATPase C6C3.06cAdd BLAST1033

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiQ10309
PaxDbiQ10309
PRIDEiQ10309

PTM databases

iPTMnetiQ10309
SwissPalmiQ10309

Interactioni

Protein-protein interaction databases

BioGridi279357, 17 interactors
STRINGi4896.SPAC6C3.06c.1

Structurei

3D structure databases

ProteinModelPortaliQ10309
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

HOGENOMiHOG000201571
InParanoidiQ10309
KOiK01530
OMAiTQNEMEM
OrthoDBiEOG092C0BQ4
PhylomeDBiQ10309

Family and domain databases

Gene3Di3.40.1110.10, 1 hit
3.40.50.1000, 1 hit
InterProiView protein in InterPro
IPR023299 ATPase_P-typ_cyto_dom_N
IPR018303 ATPase_P-typ_P_site
IPR023298 ATPase_P-typ_TM_dom_sf
IPR008250 ATPase_P-typ_transduc_dom_A_sf
IPR036412 HAD-like_sf
IPR023214 HAD_sf
IPR006539 P-type_ATPase_IV
IPR032631 P-type_ATPase_N
IPR001757 P_typ_ATPase
IPR032630 P_typ_ATPase_c
PANTHERiPTHR24092 PTHR24092, 1 hit
PfamiView protein in Pfam
PF16212 PhoLip_ATPase_C, 1 hit
PF16209 PhoLip_ATPase_N, 1 hit
SUPFAMiSSF56784 SSF56784, 1 hit
SSF81653 SSF81653, 1 hit
SSF81660 SSF81660, 1 hit
SSF81665 SSF81665, 3 hits
TIGRFAMsiTIGR01652 ATPase-Plipid, 1 hit
TIGR01494 ATPase_P-type, 2 hits
PROSITEiView protein in PROSITE
PS00154 ATPASE_E1_E2, 1 hit

Sequencei

Sequence statusi: Complete.

Q10309-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDSRLNRIQS KMKLWIKDKN LSNPSIPLKV LNKSFRSSRQ SSVSNGHGLY
60 70 80 90 100
SLDRDETESL MSSHEASNAG ISLDSSFRVI QVGQPEPQYG NNAVTNTKYD
110 120 130 140 150
LFTFLPKCLY EQFRYFYNMY FLLVSLSQLI PPLKIGYLST YIAPLIFVLL
160 170 180 190 200
ITLTKEAVDD LKRRRRDSYA NNEIYTVNDS PCAAQNIQAG DVVYIAKDQR
210 220 230 240 250
IPADMILLET TVGNEAFIRT DQLDGETDWK LRIPCSNQHT EGIVHADAPI
260 270 280 290 300
KSVHHFYGTF TLNNQKRPIS VDHTLWANTV LASDGVYGVV VYTGKDTRQS
310 320 330 340 350
MNSSKAKTKV GLLEKEINFY SKILCTFVLV LSIGLTFSHG IKTDWYISVF
360 370 380 390 400
RYLILFSSII PINLRVNLDL AKIVHSKNTE SDPNLPGVVV RSSNIPEELG
410 420 430 440 450
RIEYVLTDKT GTLTQNEMEM KKLHVGTMGF SAESMDVVQA CIQNYSTPIP
460 470 480 490 500
LSEDSKTLVR NLVLALSLCH NVTPSKGHDG VVSYQAASPD EVAIVKWTST
510 520 530 540 550
LGLVLTNRTR DAITLNNNVY KILNIFPFKS ETKRMGIIVQ SPDEKITFYL
560 570 580 590 600
KGADSIMQNF VKPSFWLEEE CGNLAREGLR TLVVAKKDLS AEEYSAFSLA
610 620 630 640 650
HSDASLSFSN SRDKKMEEIV SRYLENDMDL LGLTGVEDKL QKDVKITLEL
660 670 680 690 700
LRNAGIHVWM LTGDKVETAR CIAISSRLVS RGQYIHTINQ LSSREEAHNH
710 720 730 740 750
LLTLRNKPDS CLIIDGESME FCIGYLQNEF IDIVSDLSSV VICRCTPTQK
760 770 780 790 800
ANMTRLIQEK KQASVCCIGD GGNDVGMIQV ANVGIGIVGK EGQQASLAAD
810 820 830 840 850
YSVKEFSHVS RLLLWHGRIS YKQTSKLAMF VIHRGLLISV CQVVYSVISA
860 870 880 890 900
FEPIALFQGL LLVGYSTMYT MLPVFSIVYD RDVSEKLVFL FPELYKEMRE
910 920 930 940 950
QKCFSYKNFI SCVLISVYQG LIIQLFTFYL IGFEEEGKML AVCFSCLIFN
960 970 980 990 1000
ELIMVALQIN TWEQTIVMSE LLTLMMYILS VPFLTNYFEL KFLLGLKFYW
1010 1020 1030
VSALILFISL LPVWCGKALK RKLKPSSYAK LQR
Length:1,033
Mass (Da):116,588
Last modified:October 1, 1996 - v1
Checksum:iD57C467427D0C6D6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329670 Genomic DNA Translation: CAA93618.1
PIRiT39030
RefSeqiNP_593720.1, NM_001019151.2

Genome annotation databases

EnsemblFungiiSPAC6C3.06c.1; SPAC6C3.06c.1:pep; SPAC6C3.06c
GeneIDi2542915
KEGGispo:SPAC6C3.06c

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329670 Genomic DNA Translation: CAA93618.1
PIRiT39030
RefSeqiNP_593720.1, NM_001019151.2

3D structure databases

ProteinModelPortaliQ10309
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi279357, 17 interactors
STRINGi4896.SPAC6C3.06c.1

PTM databases

iPTMnetiQ10309
SwissPalmiQ10309

Proteomic databases

MaxQBiQ10309
PaxDbiQ10309
PRIDEiQ10309

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiSPAC6C3.06c.1; SPAC6C3.06c.1:pep; SPAC6C3.06c
GeneIDi2542915
KEGGispo:SPAC6C3.06c

Organism-specific databases

EuPathDBiFungiDB:SPAC6C3.06c
PomBaseiSPAC6C3.06c

Phylogenomic databases

HOGENOMiHOG000201571
InParanoidiQ10309
KOiK01530
OMAiTQNEMEM
OrthoDBiEOG092C0BQ4
PhylomeDBiQ10309

Enzyme and pathway databases

ReactomeiR-SPO-936837 Ion transport by P-type ATPases

Miscellaneous databases

PROiPR:Q10309

Family and domain databases

Gene3Di3.40.1110.10, 1 hit
3.40.50.1000, 1 hit
InterProiView protein in InterPro
IPR023299 ATPase_P-typ_cyto_dom_N
IPR018303 ATPase_P-typ_P_site
IPR023298 ATPase_P-typ_TM_dom_sf
IPR008250 ATPase_P-typ_transduc_dom_A_sf
IPR036412 HAD-like_sf
IPR023214 HAD_sf
IPR006539 P-type_ATPase_IV
IPR032631 P-type_ATPase_N
IPR001757 P_typ_ATPase
IPR032630 P_typ_ATPase_c
PANTHERiPTHR24092 PTHR24092, 1 hit
PfamiView protein in Pfam
PF16212 PhoLip_ATPase_C, 1 hit
PF16209 PhoLip_ATPase_N, 1 hit
SUPFAMiSSF56784 SSF56784, 1 hit
SSF81653 SSF81653, 1 hit
SSF81660 SSF81660, 1 hit
SSF81665 SSF81665, 3 hits
TIGRFAMsiTIGR01652 ATPase-Plipid, 1 hit
TIGR01494 ATPase_P-type, 2 hits
PROSITEiView protein in PROSITE
PS00154 ATPASE_E1_E2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiYD56_SCHPO
AccessioniPrimary (citable) accession number: Q10309
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: May 23, 2018
This is version 141 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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