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Entry version 167 (11 Dec 2019)
Sequence version 2 (14 Aug 2001)
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Protein

Fatty acid synthase subunit alpha

Gene

fas2

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Fatty acid synthetase catalyzes the formation of long-chain fatty acids from acetyl-CoA, malonyl-CoA and NADPH. The alpha subunit contains domains for: acyl carrier protein, 3-oxoacyl-[acyl-carrier-protein] reductase, and 3-oxoacyl-[acyl-carrier-protein] synthase. This subunit coordinates the binding of the six beta subunits to the enzyme complex.

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section is used for enzymes and indicates the residues directly involved in catalysis.<p><a href='/help/act_site' target='_top'>More...</a></p>Active sitei1262For beta-ketoacyl synthase activityBy similarity1
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section indicates at which position the protein binds a given metal ion. The nature of the metal is indicated in the ‘Description’ field.<p><a href='/help/metal' target='_top'>More...</a></p>Metal bindingi1728MagnesiumBy similarity1
Metal bindingi1729Magnesium; via carbonyl oxygenBy similarity1
Metal bindingi1730MagnesiumBy similarity1
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the interaction between a single amino acid and another chemical entity. Priority is given to the annotation of physiological ligands.<p><a href='/help/binding' target='_top'>More...</a></p>Binding sitei1754Acetyl-CoABy similarity1
Binding sitei1764Acetyl-CoABy similarity1
Metal bindingi1828MagnesiumBy similarity1
Metal bindingi1829Magnesium; via carbonyl oxygenBy similarity1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionMultifunctional enzyme, Oxidoreductase, Transferase
Biological processFatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism
LigandMagnesium, Metal-binding, NAD, NADP

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Fatty acid synthase subunit alpha (EC:2.3.1.86)
Alternative name(s):
p190/210
Including the following 3 domains:
Acyl carrier
3-oxoacyl-[acyl-carrier-protein] reductase (EC:1.1.1.100)
Alternative name(s):
Beta-ketoacyl reductase
3-oxoacyl-[acyl-carrier-protein] synthase (EC:2.3.1.41)
Alternative name(s):
Beta-ketoacyl synthase
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:fas2
Synonyms:lsd1
ORF Names:SPAC4A8.11c
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri284812 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002485 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome I

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
FungiDB:SPAC4A8.11c

Schizosaccharomyces pombe database

More...
PomBasei
SPAC4A8.11c fas2

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001802861 – 1842Fatty acid synthase subunit alphaAdd BLAST1842

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei180O-(pantetheine 4'-phosphoryl)serinePROSITE-ProRule annotation1
Modified residuei604Phosphoserine1 Publication1
Modified residuei1412Phosphoserine1 Publication1

Keywords - PTMi

Phosphopantetheine, Phosphoprotein

Proteomic databases

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q10289

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q10289

PRoteomics IDEntifications database

More...
PRIDEi
Q10289

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q10289

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

[Alpha6beta6] hexamers of two multifunctional subunits (alpha and beta).

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
280032, 6 interactors

Protein interaction database and analysis system

More...
IntActi
Q10289, 1 interactor

STRING: functional protein association networks

More...
STRINGi
4896.SPAC4A8.11c.1

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q10289

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini145 – 220CarrierPROSITE-ProRule annotationAdd BLAST76

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni? – 1842Beta-ketoacyl synthase
Regioni1728 – 1730Acetyl-CoA bindingBy similarity3
Regioni1773 – 1789Acetyl-CoA bindingBy similarityAdd BLAST17
Regioni1797 – 1800Acetyl-CoA bindingBy similarity4
Regioni1827 – 1829Acetyl-CoA bindingBy similarity3

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000177974

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q10289

KEGG Orthology (KO)

More...
KOi
K00667

Identification of Orthologs from Complete Genome Data

More...
OMAi
NRWHSES

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q10289

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.40.47.10, 3 hits
3.90.470.20, 1 hit

HAMAP database of protein families

More...
HAMAPi
MF_00101 AcpS, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR008278 4-PPantetheinyl_Trfase_dom
IPR037143 4-PPantetheinyl_Trfase_dom_sf
IPR002582 ACPS
IPR016035 Acyl_Trfase/lysoPLipase
IPR040899 Fas_alpha_ACP
IPR026025 FAS_alpha_yeast
IPR041550 FASI_helical
IPR018201 Ketoacyl_synth_AS
IPR014031 Ketoacyl_synth_C
IPR014030 Ketoacyl_synth_N
IPR036291 NAD(P)-bd_dom_sf
IPR009081 PP-bd_ACP
IPR004568 Ppantetheine-prot_Trfase_dom
IPR002347 SDR_fam
IPR016039 Thiolase-like

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01648 ACPS, 1 hit
PF00106 adh_short, 1 hit
PF18325 Fas_alpha_ACP, 1 hit
PF18314 FAS_I_H, 1 hit
PF00109 ketoacyl-synt, 1 hit
PF02801 Ketoacyl-synt_C, 1 hit

PIRSF; a whole-protein classification database

More...
PIRSFi
PIRSF000454 FAS_yeast_alpha, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF51735 SSF51735, 1 hit
SSF52151 SSF52151, 1 hit
SSF53901 SSF53901, 2 hits
SSF56214 SSF56214, 1 hit

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR00556 pantethn_trn, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00606 B_KETOACYL_SYNTHASE, 1 hit
PS50075 CARRIER, 1 hit
PS00012 PHOSPHOPANTETHEINE, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q10289-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MRPEVEQELA HTLLLELLAY QFASPVRWIE TQDVILSPPV SAERIVEIGP
60 70 80 90 100
SPTLAGMAKR TLKLKYENMD AALSINREVL CYSKDAREIY YNFEDEVADE
110 120 130 140 150
PAEAPASTSS TPKVETAAAA APAATPAPAP AQTSAPAAAL PDEPPKALEV
160 170 180 190 200
LHTLVAQKLK KSIEEVSPQK SIKDLVGGKS TLQNEILGDL QKEFGATPEK
210 220 230 240 250
PEEVPLDELG AIMQSSFNGS LGKQSSSLIS RMISSKMPGG FNNSAVRGYL
260 270 280 290 300
GNRYGLGPGR LESVLLLALT MEPASRLGSE ADAKAWLDSV AQKYAARNGV
310 320 330 340 350
TLSSPTAEGG SSSGSAAVID EETFKKLTKN NTMLVTQQLE LFARYLNKDL
360 370 380 390 400
RAGQKAQVAE KVISDTLRAQ LDLWNEEHGE FYASGIAPIF SPLKARVYDS
410 420 430 440 450
DWNWARQDAL KMFFDIIFGR LKHVDTEIVA RCISVMNRSN PTLLEFMQYH
460 470 480 490 500
IDHCPAEKGE TYQLAKTLGQ QLIDNCKSVI DAPPVFKNVN HPTAPSTTID
510 520 530 540 550
ERGNLNYEEI PRPGVRKLTH YVTEMAKGGK LPTESKNKAK VQNDLARIYR
560 570 580 590 600
IIKSQNKMSR SSKLQIKQLY GQVLHALSLP LPSSNDEQTP VKETIPFLHI
610 620 630 640 650
RKKSVDGNWE FNKSLTGTYL DVLESGAKNG ITYQDKYALV TGAGAGSIGA
660 670 680 690 700
QIVEGLLAGG AKVVVTTSRF SRKVTEFYQS LYTRHGSRGS CLIVVPFNQG
710 720 730 740 750
SKTDVEALID YIYDEKKGLG WNLDYIVPFA AIPENGREID GIDSRSEFAH
760 770 780 790 800
RIMLTNILRL LGAVKSQKAS RGMDTRPAQV ILPLSPNHGT FGNDGLYSES
810 820 830 840 850
KLGLETLFNR WYSESWANYL TICGAVIGWT RGTGLMAPNN IVSQGIEKYG
860 870 880 890 900
VRTFSQSEMA FNILGLMSQK VVDLCQSEPI YANLNGGLEL LPDLKDLSTR
910 920 930 940 950
LRTELLETAE IRRAVAAETA FDHSITNGPD SEAVFQKTAI QPRANLKFNF
960 970 980 990 1000
PKLKPYEALS HLSDLRGMVD LEKVPVVTGF SEVGPWGNSR TRWDMECYGE
1010 1020 1030 1040 1050
FSLEGCVEIA WIMGLIKNFN GKGKDGKPYS GWVDTKTGEP VDDKDVKAKY
1060 1070 1080 1090 1100
EKYILEHCGI RIIEAELFHG YNPEKKELLQ EVVIDHDLEP FEASKEAAHE
1110 1120 1130 1140 1150
FKLRHGDQVE IFEIPDSTEW SVRFKRGTSM LIPKALRFDR FVAGQIPLGW
1160 1170 1180 1190 1200
DPKRYGIPDD IISQVDPTTL YVLVSTVEAL VASGITDPYE CYKYIHVSEL
1210 1220 1230 1240 1250
GNTVGSGIGG MSALRGMYKD RWTDKPVQKD ILQESFINTA NAWINMLLLS
1260 1270 1280 1290 1300
ASGPIKTPVG ACATAVESVD AAVDLITSGK ARICISGGYD DFSEEGSYEF
1310 1320 1330 1340 1350
ANMGATSNAA KETERGRTPQ EMSRPATSTR DGFMESQGAG VQIIMQAKLA
1360 1370 1380 1390 1400
IEMGVPIHGI VGYVSTAMDK QGRSVPAPGQ GILTGAREIA TKTPLPIVDL
1410 1420 1430 1440 1450
KFRSRQLQRR RSQIGEWAER EYLYLEEELD AMKVQNPDLD LEAYRIERIN
1460 1470 1480 1490 1500
VIKEEVVRQE KEALNTFGNE FWKRDPTIAP IRGALAVWGL TIDDLGVASF
1510 1520 1530 1540 1550
HGTSTKANEK NECDVIDSQL THLGRSKGNA VYGVFQKYLT GHSKGGAGAW
1560 1570 1580 1590 1600
MLNGALQILR SGFVPGNRNA DNIDEYLARF DRVMFPSEGI QTDGIKAASV
1610 1620 1630 1640 1650
TAFGFGQVGG QVIVIHPDYI YGVIDEATYN AYKAKTAARY KASYRYTHDA
1660 1670 1680 1690 1700
LVYNNLVRAK DSPPYTKEQE KAVYLNPLAR ASKSKAGTWT FPATLPAESD
1710 1720 1730 1740 1750
ISKTNETTRT LQSLTTSLTN SNENVGVDVE LVSAISIDNE TFIERNFTDT
1760 1770 1780 1790 1800
ERKYCFAAPN PQASFAGRWS AKEAVFKSLG ISGKGAAAPL KDIEIISSES
1810 1820 1830 1840
GAPEVVLHGE AAKAATTAGV KSVSVSISHD DNQSVSVALA HK
Length:1,842
Mass (Da):202,169
Last modified:August 14, 2001 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iE4019F2D133EE571
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti107S → A in AAB39943 (Ref. 4) Curated1
Sequence conflicti422K → R in BAA11913 (PubMed:8769419).Curated1
Sequence conflicti1586P → S in BAA13877 (PubMed:9501991).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural varianti4E → V in strain: H265. 1
Natural varianti600I → N in strain: H518. 1
Natural varianti1276I → T in strain: H201. 1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
D83412 Genomic DNA Translation: BAA11913.1
AB013747 Genomic DNA Translation: BAB62029.1
AB013748 Genomic DNA Translation: BAB62030.1
AB013749 Genomic DNA Translation: BAB62031.1
AB013750 Genomic DNA Translation: BAB62032.1
CU329670 Genomic DNA Translation: CAB11481.1
U82216 Genomic DNA Translation: AAB39943.1
D89216 mRNA Translation: BAA13877.1
U97396 mRNA Translation: AAB63888.1

Protein sequence database of the Protein Information Resource

More...
PIRi
A54083
T38781
T43037
T43409

NCBI Reference Sequences

More...
RefSeqi
NP_593823.1, NM_001019252.2

Genome annotation databases

Ensembl fungal genome annotation project

More...
EnsemblFungii
SPAC4A8.11c.1; SPAC4A8.11c.1:pep; SPAC4A8.11c

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
2543618

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
spo:SPAC4A8.11c

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D83412 Genomic DNA Translation: BAA11913.1
AB013747 Genomic DNA Translation: BAB62029.1
AB013748 Genomic DNA Translation: BAB62030.1
AB013749 Genomic DNA Translation: BAB62031.1
AB013750 Genomic DNA Translation: BAB62032.1
CU329670 Genomic DNA Translation: CAB11481.1
U82216 Genomic DNA Translation: AAB39943.1
D89216 mRNA Translation: BAA13877.1
U97396 mRNA Translation: AAB63888.1
PIRiA54083
T38781
T43037
T43409
RefSeqiNP_593823.1, NM_001019252.2

3D structure databases

SMRiQ10289
ModBaseiSearch...

Protein-protein interaction databases

BioGridi280032, 6 interactors
IntActiQ10289, 1 interactor
STRINGi4896.SPAC4A8.11c.1

PTM databases

iPTMnetiQ10289

Proteomic databases

MaxQBiQ10289
PaxDbiQ10289
PRIDEiQ10289

Genome annotation databases

EnsemblFungiiSPAC4A8.11c.1; SPAC4A8.11c.1:pep; SPAC4A8.11c
GeneIDi2543618
KEGGispo:SPAC4A8.11c

Organism-specific databases

EuPathDBiFungiDB:SPAC4A8.11c
PomBaseiSPAC4A8.11c fas2

Phylogenomic databases

HOGENOMiHOG000177974
InParanoidiQ10289
KOiK00667
OMAiNRWHSES
PhylomeDBiQ10289

Miscellaneous databases

Protein Ontology

More...
PROi
PR:Q10289

Family and domain databases

Gene3Di3.40.47.10, 3 hits
3.90.470.20, 1 hit
HAMAPiMF_00101 AcpS, 1 hit
InterProiView protein in InterPro
IPR008278 4-PPantetheinyl_Trfase_dom
IPR037143 4-PPantetheinyl_Trfase_dom_sf
IPR002582 ACPS
IPR016035 Acyl_Trfase/lysoPLipase
IPR040899 Fas_alpha_ACP
IPR026025 FAS_alpha_yeast
IPR041550 FASI_helical
IPR018201 Ketoacyl_synth_AS
IPR014031 Ketoacyl_synth_C
IPR014030 Ketoacyl_synth_N
IPR036291 NAD(P)-bd_dom_sf
IPR009081 PP-bd_ACP
IPR004568 Ppantetheine-prot_Trfase_dom
IPR002347 SDR_fam
IPR016039 Thiolase-like
PfamiView protein in Pfam
PF01648 ACPS, 1 hit
PF00106 adh_short, 1 hit
PF18325 Fas_alpha_ACP, 1 hit
PF18314 FAS_I_H, 1 hit
PF00109 ketoacyl-synt, 1 hit
PF02801 Ketoacyl-synt_C, 1 hit
PIRSFiPIRSF000454 FAS_yeast_alpha, 1 hit
SUPFAMiSSF51735 SSF51735, 1 hit
SSF52151 SSF52151, 1 hit
SSF53901 SSF53901, 2 hits
SSF56214 SSF56214, 1 hit
TIGRFAMsiTIGR00556 pantethn_trn, 1 hit
PROSITEiView protein in PROSITE
PS00606 B_KETOACYL_SYNTHASE, 1 hit
PS50075 CARRIER, 1 hit
PS00012 PHOSPHOPANTETHEINE, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiFAS2_SCHPO
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q10289
Secondary accession number(s): O14163
, P78866, P78973, Q96WT6, Q96WT7, Q96WT8, Q9URI5
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: August 14, 2001
Last modified: December 11, 2019
This is version 167 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Direct protein sequencing, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
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