Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

UniProtKB - Q10185 (ABC2_SCHPO)

Entry version 145 (13 Feb 2019)
Sequence version 1 (01 Oct 1996)
Previous versions | rss
Other tutorials and videosHelp videoFeedback
Protein

ATP-binding cassette transporter abc2

Gene

abc2

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Involved in vacuolar sequestration of glutathione S-conjugates. Together with abc4, required for accumulation of a red pigment (ade pigment) in the vacuole of a mutant affected in the adenine biosynthetic pathway.1 Publication

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Function’ section describes a region in the protein which binds nucleotide phosphates. It always involves more than one amino acid and includes all residues involved in nucleotide-binding.<p><a href='/help/np_bind' target='_top'>More...</a></p>Nucleotide bindingi631 – 638ATP 1PROSITE-ProRule annotation8
Nucleotide bindingi1273 – 1280ATP 2PROSITE-ProRule annotation8

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • ATPase activity, coupled to transmembrane movement of substances Source: GO_Central
  • ATP binding Source: UniProtKB-KW
  • phytochelatin transmembrane transporter ATPase activity Source: PomBase
View the complete GO annotation on QuickGO ...

GO - Biological processi

View the complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionHydrolase
Biological processDetoxification, Transport
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...Reactomei		R-SPO-196741 Cobalamin (Cbl, vitamin B12) transport and metabolism
R-SPO-2142691 Synthesis of Leukotrienes (LT) and Eoxins (EX)
R-SPO-382556 ABC-family proteins mediated transport

Protein family/group databases

Transport Classification Database

More...TCDBi		3.A.1.208.16 the atp-binding cassette (abc) superfamily

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
ATP-binding cassette transporter abc2 (EC:3.6.3.-)
Short name:
ABC transporter abc2
Alternative name(s):
ATP-energized glutathione S-conjugate pump abc2
Glutathione S-conjugate-transporting ATPase abc2
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:abc2
ORF Names:SPAC3F10.11c
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri284812 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Fungi › Dikarya › Ascomycota › Taphrinomycotina › Schizosaccharomycetes › Schizosaccharomycetales › Schizosaccharomycetaceae › Schizosaccharomyces ›
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002485 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome I

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...EuPathDBi		FungiDB:SPAC3F10.11c

Schizosaccharomyces pombe database

More...PomBasei		SPAC3F10.11c abc2

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini1 – 25VacuolarBy similarityAdd BLAST25
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei26 – 46Helical; Name=1PROSITE-ProRule annotationAdd BLAST21
Topological domaini47 – 65CytoplasmicBy similarityAdd BLAST19
Transmembranei66 – 85Helical; Name=2PROSITE-ProRule annotationAdd BLAST20
Topological domaini86 – 90VacuolarBy similarity5
Transmembranei91 – 104Helical; Name=3PROSITE-ProRule annotationAdd BLAST14
Topological domaini105 – 116CytoplasmicBy similarityAdd BLAST12
Transmembranei117 – 137Helical; Name=4PROSITE-ProRule annotationAdd BLAST21
Topological domaini138 – 154VacuolarBy similarityAdd BLAST17
Transmembranei155 – 175Helical; Name=5PROSITE-ProRule annotationAdd BLAST21
Topological domaini176 – 259CytoplasmicBy similarityAdd BLAST84
Transmembranei260 – 280Helical; Name=6PROSITE-ProRule annotationAdd BLAST21
Topological domaini281 – 310VacuolarBy similarityAdd BLAST30
Transmembranei311 – 331Helical; Name=7PROSITE-ProRule annotationAdd BLAST21
Topological domaini332 – 387CytoplasmicBy similarityAdd BLAST56
Transmembranei388 – 408Helical; Name=8PROSITE-ProRule annotationAdd BLAST21
Topological domaini409 – 411VacuolarBy similarity3
Transmembranei412 – 432Helical; Name=9PROSITE-ProRule annotationAdd BLAST21
Topological domaini433 – 495CytoplasmicBy similarityAdd BLAST63
Transmembranei496 – 516Helical; Name=10PROSITE-ProRule annotationAdd BLAST21
Topological domaini517 – 539VacuolarBy similarityAdd BLAST23
Transmembranei540 – 560Helical; Name=11PROSITE-ProRule annotationAdd BLAST21
Topological domaini561 – 910CytoplasmicBy similarityAdd BLAST350
Transmembranei911 – 931Helical; Name=12PROSITE-ProRule annotationAdd BLAST21
Topological domaini932 – 968VacuolarBy similarityAdd BLAST37
Transmembranei969 – 990Helical; Name=13PROSITE-ProRule annotationAdd BLAST22
Topological domaini991 – 1033CytoplasmicBy similarityAdd BLAST43
Transmembranei1034 – 1054Helical; Name=14PROSITE-ProRule annotationAdd BLAST21
Topological domaini1055VacuolarBy similarity1
Transmembranei1056 – 1076Helical; Name=15PROSITE-ProRule annotationAdd BLAST21
Topological domaini1077 – 1147CytoplasmicBy similarityAdd BLAST71
Transmembranei1148 – 1168Helical; Name=16PROSITE-ProRule annotationAdd BLAST21
Topological domaini1169 – 1172VacuolarBy similarity4
Transmembranei1173 – 1193Helical; Name=17PROSITE-ProRule annotationAdd BLAST21
Topological domaini1194 – 1478CytoplasmicBy similarityAdd BLAST285

Keywords - Cellular componenti

Membrane, Vacuole

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the ‘Pathology and Biotech’ section describes the in vivo effects caused by ablation of the gene (or one or more transcripts) coding for the protein described in the entry. This includes gene knockout and knockdown, provided experiments have been performed in the context of a whole organism or a specific tissue, and not at the single-cell level.<p><a href='/help/disruption_phenotype' target='_top'>More...</a></p>Disruption phenotypei

Cells lacking both abc2 and abc4 show sensitivity to cycloheximide (CHX) and 4-nitroquinoline oxide (4-NQO), and decreased accumulation of monochlorobimane-glutathione (MCIB-GS).1 Publication

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000934681 – 1478ATP-binding cassette transporter abc2Add BLAST1478

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi86N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi139N-linked (GlcNAc...) asparagineSequence analysis1
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei839Phosphoserine1 Publication1
Modified residuei843Phosphoserine1 Publication1
Modified residuei863Phosphoserine1 Publication1

Keywords - PTMi

Glycoprotein, Phosphoprotein

Proteomic databases

MaxQB - The MaxQuant DataBase

More...MaxQBi		Q10185

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q10185

PRoteomics IDEntifications database

More...PRIDEi		Q10185

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q10185

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...BioGridi		279622, 21 interactors

STRING: functional protein association networks

More...STRINGi		4896.SPAC3F10.11c.1

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...ProteinModelPortali		Q10185

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q10185

Database of comparative protein structure models

More...ModBasei		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini268 – 557ABC transmembrane type-1 1PROSITE-ProRule annotationAdd BLAST290
Domaini593 – 821ABC transporter 1PROSITE-ProRule annotationAdd BLAST229
Domaini918 – 1202ABC transmembrane type-1 2PROSITE-ProRule annotationAdd BLAST285
Domaini1239 – 1473ABC transporter 2PROSITE-ProRule annotationAdd BLAST235

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily. [View classification]Curated

Keywords - Domaini

Repeat, Transmembrane, Transmembrane helix

Phylogenomic databases

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q10185

KEGG Orthology (KO)

More...KOi		K05665

Identification of Orthologs from Complete Genome Data

More...OMAi		NEWRVDA

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q10185

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		1.20.1560.10, 2 hits

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR003593 AAA+_ATPase
IPR011527 ABC1_TM_dom
IPR036640 ABC1_TM_sf
IPR003439 ABC_transporter-like
IPR017871 ABC_transporter_CS
IPR027417 P-loop_NTPase

Pfam protein domain database

More...Pfami		View protein in Pfam
PF00664 ABC_membrane, 2 hits
PF00005 ABC_tran, 2 hits

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00382 AAA, 2 hits

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF52540 SSF52540, 2 hits
SSF90123 SSF90123, 2 hits

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS50929 ABC_TM1F, 2 hits
PS00211 ABC_TRANSPORTER_1, 1 hit
PS50893 ABC_TRANSPORTER_2, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q10185-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MVLEQDLDPF VGGNWMNSAY KGFTFLSATW LAPNIYLLIS GCLQYFYEVR 
        60         70         80         90        100
KRSHYFHFRR FWTIWLKSLV IMVLLFTHIY DCYKTNESVW NVLSIITYFL 
       110        120        130        140        150
ALFLHVVEQP TLRIPMASLL MFWLFKFLAS ALVLLLRPNY TMFPMLNVVP 
       160        170        180        190        200
SITFFCSLVC LLAEIYVPPA NRVWYPDDAA ELEETGLRPS RFTYANIFSR 
       210        220        230        240        250
ISFGWLSPLM KFGYRNYLTE SDAWSLPPAE RSSNLTIVFE KNWISHAKKK 
       260        270        280        290        300
KSSLYMWGVL FLNHWKLTVV IIVLKLVQDV VAFIQPNLIR KIVIFVSSYS 
       310        320        330        340        350
SEHPQPPQVG FSLAIAMFLT NVVQTALLQQ YFQLGMVLGM RWRSELITAI 
       360        370        380        390        400
YRKSLRLSSA ARQSRSVGDI VNYMSVDTQK VCDLTMFLFV IVSGPFQIVL 
       410        420        430        440        450
ALTNLYHLVG YGALSGAFVT FLLFPCNVVI ASIFKRFQNR QMKNKDARSQ 
       460        470        480        490        500
FMTEIINNIR SIKLYAWENI FLQKLLQLRN TRELRMLKKI GIVNTIGNFT 
       510        520        530        540        550
WLFAPILVSA ATFGTFIVLY GKTRVLSVDI VFACLSLFNL LQFPLTMLPI 
       560        570        580        590        600
VVSSVLEASV AISRIYGFLT AGELDSNAVQ RYPANKEPSG VCLEIKKGTF 
       610        620        630        640        650
SWSGPGQNAA EPTLRDIDFV ARRGELCCIV GKVGMGKSSL LEACLGNMQK 
       660        670        680        690        700
HSGSVFRCGS IAYAAQQPWI LNATIQENIL FGLELDPEFY EKTIRACCLL 
       710        720        730        740        750
RDFEILADGD QTEVGEKGIS LSGGQKARIS LARAVYSRSD IYLLDDILSA 
       760        770        780        790        800
VDQHVNRDLV RNLLGSKGLL RSRCVILSTN SLTVLKEASM IYMLRNGKII 
       810        820        830        840        850
ESGSFTQLSS SPDSQLFQLL SEFSKKDTAS STGADTPLSR SQSVITSSTD 
       860        870        880        890        900
VTSSASRSSD TVSNYPKATI KGTGRIRKRL TDEDNVKATG QAAEKMERGK 
       910        920        930        940        950
VKWKVYWTYF KACSLFLIFL YFLFIIGGIG MNVGTNVWLK HWSEVNTQLG 
       960        970        980        990       1000
YNPKPYFYLG IYTLFGLLSC ALISLSSLTI TVFCAIKSCR YLHDSMVKAV 
      1010       1020       1030       1040       1050
LRAPMSFFET TPTGRILNRF SSDVYRVDEV ISRVFMFFFR NLFQIVFVLA 
      1060       1070       1080       1090       1100
VICYSSPMFM ILIVPLFFLY RYNQVYYTQT SRELKRLDSV TRSPLYAHFQ 
      1110       1120       1130       1140       1150
ESLGGLSTIR AYDMEDTFIS ENDIRVDTNH RIWFLYFSSN RWQAIRVEAI 
      1160       1170       1180       1190       1200
GALVVFSSAF FGVLSAVRGN PNSGLVGLSL SYAVQITQSL TFVVRQSVDV 
      1210       1220       1230       1240       1250
ETNIVSVERM LEYIGLPSEA PSIIPDHRPP EGWPSHGAIK FDHYSVRYRE 
      1260       1270       1280       1290       1300
NLPLVLNDIS VNIKPQEKIG IVGRTGAGKS TLTLALFRLI EPTSGDIQLD 
      1310       1320       1330       1340       1350
DINITSIGLH DLRSRLAIIP QENQAFEGTI RENLDPNANA TDEEIWHALE 
      1360       1370       1380       1390       1400
AASLKQFIQT LDGGLYSRVT EGGANLSSGQ RQLMCLTRAL LTPTRVLLLD 
      1410       1420       1430       1440       1450
EATAAVDVET DAIVQRTIRE RFNDRTILTI AHRINTVMDS NRILVLDHGK 
      1460       1470 
VVEFDSTKKL LENKASLFYS LAKESGLI
Length:1,478
Mass (Da):166,938
Last modified:October 1, 1996 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i6C59F43105EB7187
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti1287F → L in BAA13892 (PubMed:9501991).Curated1
Sequence conflicti1301 – 1303DIN → YIH in BAA13892 (PubMed:9501991).Curated3
Sequence conflicti1311D → H in BAA13892 (PubMed:9501991).Curated1
Sequence conflicti1467L → V in BAA13892 (PubMed:9501991).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
CU329670 Genomic DNA Translation: CAA93309.3
D89231 mRNA Translation: BAA13892.1

Protein sequence database of the Protein Information Resource

More...PIRi		T38712

NCBI Reference Sequences

More...RefSeqi		NP_593943.3, NM_001019371.3

Genome annotation databases

Ensembl fungal genome annotation project

More...EnsemblFungii		SPAC3F10.11c.1; SPAC3F10.11c.1:pep; SPAC3F10.11c

Database of genes from NCBI RefSeq genomes

More...GeneIDi		2543193

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		spo:SPAC3F10.11c

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329670 Genomic DNA Translation: CAA93309.3
D89231 mRNA Translation: BAA13892.1
PIRiT38712
RefSeqiNP_593943.3, NM_001019371.3

3D structure databases

ProteinModelPortaliQ10185
SMRiQ10185
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi279622, 21 interactors
STRINGi4896.SPAC3F10.11c.1

Protein family/group databases

TCDBi3.A.1.208.16 the atp-binding cassette (abc) superfamily

PTM databases

iPTMnetiQ10185

Proteomic databases

MaxQBiQ10185
PaxDbiQ10185
PRIDEiQ10185

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiSPAC3F10.11c.1; SPAC3F10.11c.1:pep; SPAC3F10.11c
GeneIDi2543193
KEGGispo:SPAC3F10.11c

Organism-specific databases

EuPathDBiFungiDB:SPAC3F10.11c
PomBaseiSPAC3F10.11c abc2

Phylogenomic databases

InParanoidiQ10185
KOiK05665
OMAiNEWRVDA
PhylomeDBiQ10185

Enzyme and pathway databases

ReactomeiR-SPO-196741 Cobalamin (Cbl, vitamin B12) transport and metabolism
R-SPO-2142691 Synthesis of Leukotrienes (LT) and Eoxins (EX)
R-SPO-382556 ABC-family proteins mediated transport

Miscellaneous databases

Protein Ontology

More...PROi		PR:Q10185

Family and domain databases

Gene3Di1.20.1560.10, 2 hits
InterProiView protein in InterPro
IPR003593 AAA+_ATPase
IPR011527 ABC1_TM_dom
IPR036640 ABC1_TM_sf
IPR003439 ABC_transporter-like
IPR017871 ABC_transporter_CS
IPR027417 P-loop_NTPase
PfamiView protein in Pfam
PF00664 ABC_membrane, 2 hits
PF00005 ABC_tran, 2 hits
SMARTiView protein in SMART
SM00382 AAA, 2 hits
SUPFAMiSSF52540 SSF52540, 2 hits
SSF90123 SSF90123, 2 hits
PROSITEiView protein in PROSITE
PS50929 ABC_TM1F, 2 hits
PS00211 ABC_TRANSPORTER_1, 1 hit
PS50893 ABC_TRANSPORTER_2, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiABC2_SCHPO
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q10185
Secondary accession number(s): P78928
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: February 13, 2019
This is version 145 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again