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Protein

Fatty acid-binding protein 9

Gene

FABP9

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processTransport
LigandLipid-binding

Enzyme and pathway databases

ReactomeiR-HSA-163560 Triglyceride catabolism

Names & Taxonomyi

Protein namesi
Recommended name:
Fatty acid-binding protein 9
Alternative name(s):
Testis lipid-binding protein
Short name:
TLBP
Testis-type fatty acid-binding protein
Short name:
T-FABP
Gene namesi
Name:FABP9
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 8

Organism-specific databases

EuPathDBiHostDB:ENSG00000205186.2
HGNCiHGNC:3563 FABP9
neXtProtiNX_Q0Z7S8

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm

Pathology & Biotechi

Organism-specific databases

DisGeNETi646480
OpenTargetsiENSG00000205186
PharmGKBiPA27964

Chemistry databases

ChEMBLiCHEMBL3826865

Polymorphism and mutation databases

BioMutaiFABP9
DMDMi121948152

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003172921 – 132Fatty acid-binding protein 9Add BLAST132

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei13PhosphoserineBy similarity1
Modified residuei14PhosphoserineBy similarity1
Modified residuei44PhosphoserineBy similarity1
Modified residuei91PhosphoserineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiQ0Z7S8
PeptideAtlasiQ0Z7S8
PRIDEiQ0Z7S8
ProteomicsDBi58847

PTM databases

iPTMnetiQ0Z7S8
PhosphoSitePlusiQ0Z7S8

Expressioni

Gene expression databases

BgeeiENSG00000205186 Expressed in 37 organ(s), highest expression level in subcutaneous adipose tissue
CleanExiHS_FABP9

Organism-specific databases

HPAiHPA073619

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000368362

Structurei

Secondary structure

1132
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

ProteinModelPortaliQ0Z7S8
SMRiQ0Z7S8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG4015 Eukaryota
ENOG4111US8 LUCA
GeneTreeiENSGT00760000118898
HOGENOMiHOG000004829
HOVERGENiHBG005633
InParanoidiQ0Z7S8
OMAiEKMVVEC
OrthoDBiEOG091G0QSV
PhylomeDBiQ0Z7S8
TreeFamiTF316894

Family and domain databases

Gene3Di2.40.128.20, 1 hit
InterProiView protein in InterPro
IPR012674 Calycin
IPR000463 Fatty_acid-bd
IPR031259 ILBP
IPR000566 Lipocln_cytosolic_FA-bd_dom
PANTHERiPTHR11955 PTHR11955, 1 hit
PfamiView protein in Pfam
PF00061 Lipocalin, 1 hit
PRINTSiPR00178 FATTYACIDBP
SUPFAMiSSF50814 SSF50814, 1 hit
PROSITEiView protein in PROSITE
PS00214 FABP, 1 hit

Sequencei

Sequence statusi: Complete.

Q0Z7S8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MVEPFLGTWK LVSSENFEDY MKELGVNFAA RNMAGLVKPT VTISVDGKMM
60 70 80 90 100
TIRTESSFQD TKISFKLGEE FDETTADNRK VKSTITLENG SMIHVQKWLG
110 120 130
KETTIKRKIV DEKMVVECKM NNIVSTRIYE KV
Length:132
Mass (Da):15,093
Last modified:August 22, 2006 - v1
Checksum:iB189DA5EB0B234FA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DQ821473 Genomic DNA Translation: ABG49443.1
CH471068 Genomic DNA Translation: EAW87091.1
RefSeqiNP_001073995.1, NM_001080526.1
UniGeneiHs.653176

Genome annotation databases

EnsembliENST00000379071; ENSP00000368362; ENSG00000205186
GeneIDi646480
KEGGihsa:646480
UCSCiuc011lfo.3 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DQ821473 Genomic DNA Translation: ABG49443.1
CH471068 Genomic DNA Translation: EAW87091.1
RefSeqiNP_001073995.1, NM_001080526.1
UniGeneiHs.653176

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
4A60X-ray1.53A1-132[»]
ProteinModelPortaliQ0Z7S8
SMRiQ0Z7S8
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000368362

Chemistry databases

ChEMBLiCHEMBL3826865

PTM databases

iPTMnetiQ0Z7S8
PhosphoSitePlusiQ0Z7S8

Polymorphism and mutation databases

BioMutaiFABP9
DMDMi121948152

Proteomic databases

PaxDbiQ0Z7S8
PeptideAtlasiQ0Z7S8
PRIDEiQ0Z7S8
ProteomicsDBi58847

Protocols and materials databases

DNASUi646480
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000379071; ENSP00000368362; ENSG00000205186
GeneIDi646480
KEGGihsa:646480
UCSCiuc011lfo.3 human

Organism-specific databases

CTDi646480
DisGeNETi646480
EuPathDBiHostDB:ENSG00000205186.2
GeneCardsiFABP9
HGNCiHGNC:3563 FABP9
HPAiHPA073619
neXtProtiNX_Q0Z7S8
OpenTargetsiENSG00000205186
PharmGKBiPA27964
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG4015 Eukaryota
ENOG4111US8 LUCA
GeneTreeiENSGT00760000118898
HOGENOMiHOG000004829
HOVERGENiHBG005633
InParanoidiQ0Z7S8
OMAiEKMVVEC
OrthoDBiEOG091G0QSV
PhylomeDBiQ0Z7S8
TreeFamiTF316894

Enzyme and pathway databases

ReactomeiR-HSA-163560 Triglyceride catabolism

Miscellaneous databases

GenomeRNAii646480
PROiPR:Q0Z7S8

Gene expression databases

BgeeiENSG00000205186 Expressed in 37 organ(s), highest expression level in subcutaneous adipose tissue
CleanExiHS_FABP9

Family and domain databases

Gene3Di2.40.128.20, 1 hit
InterProiView protein in InterPro
IPR012674 Calycin
IPR000463 Fatty_acid-bd
IPR031259 ILBP
IPR000566 Lipocln_cytosolic_FA-bd_dom
PANTHERiPTHR11955 PTHR11955, 1 hit
PfamiView protein in Pfam
PF00061 Lipocalin, 1 hit
PRINTSiPR00178 FATTYACIDBP
SUPFAMiSSF50814 SSF50814, 1 hit
PROSITEiView protein in PROSITE
PS00214 FABP, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiFABP9_HUMAN
AccessioniPrimary (citable) accession number: Q0Z7S8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: August 22, 2006
Last modified: September 12, 2018
This is version 96 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. Human chromosome 8
    Human chromosome 8: entries, gene names and cross-references to MIM
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Main funding by: National Institutes of Health

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