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Entry version 100 (16 Jan 2019)
Sequence version 2 (01 May 2007)
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Protein

Coatomer subunit gamma

Gene

At4g34450

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins (By similarity).By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processER-Golgi transport, Protein transport, Transport

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-ATH-6807878 COPI-mediated anterograde transport
R-ATH-6811434 COPI-dependent Golgi-to-ER retrograde traffic

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Coatomer subunit gamma
Alternative name(s):
Gamma-coat protein
Short name:
Gamma-COP
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Ordered Locus Names:At4g34450
ORF Names:T4L20.30
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiArabidopsis thaliana (Mouse-ear cress)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri3702 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000006548 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 4

Organism-specific databases

Arabidopsis Information Portal

More...
Araporti
AT4G34450

The Arabidopsis Information Resource

More...
TAIRi
locus:2139479 AT4G34450

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Cytoplasmic vesicle, Golgi apparatus, Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002856271 – 886Coatomer subunit gammaAdd BLAST886

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q0WW26

PRoteomics IDEntifications database

More...
PRIDEi
Q0WW26

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q0WW26

SwissPalm database of S-palmitoylation events

More...
SwissPalmi
Q0WW26

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q0WW26 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q0WW26 AT

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.By similarity

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
14878, 3 interactors

Protein interaction database and analysis system

More...
IntActi
Q0WW26, 1 interactor

STRING: functional protein association networks

More...
STRINGi
3702.AT4G34450.1

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
Q0WW26

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati66 – 103HEAT 1Add BLAST38
Repeati288 – 325HEAT 2Add BLAST38
Repeati327 – 359HEAT 3Add BLAST33
Repeati360 – 397HEAT 4Add BLAST38
Repeati472 – 509HEAT 5Add BLAST38

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the COPG family.Curated

Keywords - Domaini

Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1078 Eukaryota
COG5240 LUCA

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000184434

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q0WW26

KEGG Orthology (KO)

More...
KOi
K17267

Identification of Orthologs from Complete Genome Data

More...
OMAi
PVNARKC

Database of Orthologous Groups

More...
OrthoDBi
255234at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q0WW26

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.25.10.10, 1 hit
2.60.40.1480, 1 hit
3.30.310.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR011989 ARM-like
IPR016024 ARM-type_fold
IPR002553 Clathrin/coatomer_adapt-like_N
IPR013041 Clathrin_app_Ig-like_sf
IPR009028 Coatomer/calthrin_app_sub_C
IPR032154 Coatomer_g_Cpla
IPR017106 Coatomer_gsu
IPR013040 Coatomer_gsu_app_Ig-like_dom
IPR037067 Coatomer_gsu_app_sf
IPR012295 TBP_dom_sf

The PANTHER Classification System

More...
PANTHERi
PTHR10261 PTHR10261, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01602 Adaptin_N, 1 hit
PF16381 Coatomer_g_Cpla, 1 hit
PF08752 COP-gamma_platf, 1 hit

PIRSF; a whole-protein classification database

More...
PIRSFi
PIRSF037093 Coatomer_gamma_subunit, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48371 SSF48371, 1 hit
SSF49348 SSF49348, 1 hit
SSF55711 SSF55711, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q0WW26-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAQPLVKKDD DHDDELEYSP FMGIEKGAVL QEARVFNDPQ VDPRRCSQVI
60 70 80 90 100
TKLLYLLNQG ESFTKVEATE VFFSVTKLFQ SKDTGLRRMV YLIIKELSPS
110 120 130 140 150
SDEVIIVTSS LMKDMNSKID MYRANAIRVL CRIIDGTLLT QIERYLKQAI
160 170 180 190 200
VDKNPVVSSA ALVSGLHLLK TNPEIVKRWS NEVQEGIQSR SALVQFHALA
210 220 230 240 250
LLHQIRQNDR LAVSKLVGSL TRGSVRSPLA QCLLIRYTSQ VIRDMANHGQ
260 270 280 290 300
SGERPFYEFL ESCLRHKAEM VILEAARAIT ELDGVTSREL TPAITVLQLF
310 320 330 340 350
LSSPRPVLRF AAVRTLNKVA MTHPMAVTNC NIDMESLISD QNRSIATLAI
360 370 380 390 400
TTLLKTGNES SVERLMKQIT NFMSDIADEF KIVVVDAIRS LCVKFPLKYR
410 420 430 440 450
SLMTFLSNIL REEGGFEYKR AIVDSIVTII RDIPDAKESG LLHLCEFIED
460 470 480 490 500
CEFTYLSTQI LHFLGIEGPN TSDPSKYIRY IYNRVHLENA TVRAAAVSTL
510 520 530 540 550
AKFGFMVESL KPRITVLLKR CIYDSDDEVR DRATLYLSVL GGDGTVDTDK
560 570 580 590 600
ESKDFLFGSL EVPLVNMETS LKNYEPSEEA FDINSVPKEV KSQPLAEKKA
610 620 630 640 650
QGKKPTGLGA PPAAPASGFD GYERLLSSIP EFAAFGKLFK SSLPVELTEA
660 670 680 690 700
ETEYAVNVVK HIFDSHVVFQ YNCTNTIPEQ LLERVNVIVD ASEAEEFSEV
710 720 730 740 750
TSKALNSLPY DSPGQAFVVF EKPAGVPAVG KFSNTLTFVV KEVDPSTGEA
760 770 780 790 800
EDDGVEDEYQ LEDLEVVAGD YMVKVGVSNF RNAWESMDEE DERVDEYGLG
810 820 830 840 850
QRESLGEAVK AVMDLLGMQT CEGTETIPLN ARSHTCLLSG VYIGNVKVLV
860 870 880
RAQFGMDSSK DIAMKLTVRA EDVSVAEAIH EIVASG
Length:886
Mass (Da):98,491
Last modified:May 1, 2007 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i188840F332D97CAF
GO

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence CAA18824 differs from that shown. Reason: Erroneous gene model prediction.Curated
The sequence CAB80162 differs from that shown. Reason: Erroneous gene model prediction.Curated

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AL023094 Genomic DNA Translation: CAA18824.1 Sequence problems.
AL161585 Genomic DNA Translation: CAB80162.1 Sequence problems.
CP002687 Genomic DNA Translation: AEE86378.1
AK221839 mRNA Translation: BAD94079.1
AK226533 mRNA Translation: BAE98672.1

Protein sequence database of the Protein Information Resource

More...
PIRi
T05265

NCBI Reference Sequences

More...
RefSeqi
NP_195171.2, NM_119610.4

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
At.25572

Genome annotation databases

Ensembl plant genome annotation project

More...
EnsemblPlantsi
AT4G34450.1; AT4G34450.1; AT4G34450

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
829596

Gramene; a comparative resource for plants

More...
Gramenei
AT4G34450.1; AT4G34450.1; AT4G34450

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
ath:AT4G34450

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL023094 Genomic DNA Translation: CAA18824.1 Sequence problems.
AL161585 Genomic DNA Translation: CAB80162.1 Sequence problems.
CP002687 Genomic DNA Translation: AEE86378.1
AK221839 mRNA Translation: BAD94079.1
AK226533 mRNA Translation: BAE98672.1
PIRiT05265
RefSeqiNP_195171.2, NM_119610.4
UniGeneiAt.25572

3D structure databases

ProteinModelPortaliQ0WW26
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi14878, 3 interactors
IntActiQ0WW26, 1 interactor
STRINGi3702.AT4G34450.1

PTM databases

iPTMnetiQ0WW26
SwissPalmiQ0WW26

Proteomic databases

PaxDbiQ0WW26
PRIDEiQ0WW26

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT4G34450.1; AT4G34450.1; AT4G34450
GeneIDi829596
GrameneiAT4G34450.1; AT4G34450.1; AT4G34450
KEGGiath:AT4G34450

Organism-specific databases

AraportiAT4G34450
TAIRilocus:2139479 AT4G34450

Phylogenomic databases

eggNOGiKOG1078 Eukaryota
COG5240 LUCA
HOGENOMiHOG000184434
InParanoidiQ0WW26
KOiK17267
OMAiPVNARKC
OrthoDBi255234at2759
PhylomeDBiQ0WW26

Enzyme and pathway databases

ReactomeiR-ATH-6807878 COPI-mediated anterograde transport
R-ATH-6811434 COPI-dependent Golgi-to-ER retrograde traffic

Miscellaneous databases

Protein Ontology

More...
PROi
PR:Q0WW26

Gene expression databases

ExpressionAtlasiQ0WW26 baseline and differential
GenevisibleiQ0WW26 AT

Family and domain databases

Gene3Di1.25.10.10, 1 hit
2.60.40.1480, 1 hit
3.30.310.10, 1 hit
InterProiView protein in InterPro
IPR011989 ARM-like
IPR016024 ARM-type_fold
IPR002553 Clathrin/coatomer_adapt-like_N
IPR013041 Clathrin_app_Ig-like_sf
IPR009028 Coatomer/calthrin_app_sub_C
IPR032154 Coatomer_g_Cpla
IPR017106 Coatomer_gsu
IPR013040 Coatomer_gsu_app_Ig-like_dom
IPR037067 Coatomer_gsu_app_sf
IPR012295 TBP_dom_sf
PANTHERiPTHR10261 PTHR10261, 1 hit
PfamiView protein in Pfam
PF01602 Adaptin_N, 1 hit
PF16381 Coatomer_g_Cpla, 1 hit
PF08752 COP-gamma_platf, 1 hit
PIRSFiPIRSF037093 Coatomer_gamma_subunit, 1 hit
SUPFAMiSSF48371 SSF48371, 1 hit
SSF49348 SSF49348, 1 hit
SSF55711 SSF55711, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiCOPG_ARATH
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q0WW26
Secondary accession number(s): O65673, Q56X38
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 1, 2007
Last sequence update: May 1, 2007
Last modified: January 16, 2019
This is version 100 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
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