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Entry version 111 (16 Oct 2019)
Sequence version 1 (05 Sep 2006)
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Protein

1-phosphatidylinositol-3-phosphate 5-kinase FAB1A

Gene

FAB1A

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

The PI(3,5)P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). Catalyzes the phosphorylation of phosphatidylinositol 3-phosphate on the fifth hydroxyl of the myo-inositol ring, to form phosphatidylinositol 3,5-bisphosphate (By similarity). Plays an important role in maintenance of endomembrane homeostasis including endocytosis, vacuole formation, and vacuolar acidification processes. Required for development of viable pollen. Might mediate recycling of auxin transporters.By similarity3 Publications

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>This subsection of the ‘Function’ section provides information relevant to cofactors. A cofactor is any non-protein substance required for a protein to be catalytically active. Some cofactors are inorganic, such as the metal atoms zinc, iron, and copper in various oxidation states. Others, such as most vitamins, are organic.<p><a href='/help/cofactor' target='_top'>More...</a></p>Cofactori

Mg2+By similarity, Mn2+By similarity

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri36 – 102FYVE-typePROSITE-ProRule annotationAdd BLAST67

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • 1-phosphatidylinositol-3-phosphate 5-kinase activity Source: TAIR
  • ATP binding Source: UniProtKB-KW
  • metal ion binding Source: UniProtKB-KW

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionKinase, Transferase
LigandATP-binding, Metal-binding, Nucleotide-binding, Zinc

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...
BioCyci
ARA:AT4G33240-MONOMER

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
1-phosphatidylinositol-3-phosphate 5-kinase FAB1A (EC:2.7.1.150)
Short name:
Phosphatidylinositol 3-phosphate 5-kinase
Alternative name(s):
FYVE finger-containing phosphoinositide kinase
PIKfyve
Phosphatidylinositol 3-phosphate 5-kinase type III
Short name:
PIPkin-III
Short name:
Type III PIP kinase
Protein FORMS APLOID AND BINUCLEATE CELLS 1A
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:FAB1A
Ordered Locus Names:At4g33240
ORF Names:F4I10.170
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiArabidopsis thaliana (Mouse-ear cress)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri3702 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliopsidaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000006548 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 4

Organism-specific databases

Arabidopsis Information Portal

More...
Araporti
AT4G33240

The Arabidopsis Information Resource

More...
TAIRi
locus:2125884 AT4G33240

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Endosome, Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the ‘Pathology and Biotech’ section describes the in vivo effects caused by ablation of the gene (or one or more transcripts) coding for the protein described in the entry. This includes gene knockout and knockdown, provided experiments have been performed in the context of a whole organism or a specific tissue, and not at the single-cell level.<p><a href='/help/disruption_phenotype' target='_top'>More...</a></p>Disruption phenotypei

Leaf-curling phenotype. Root growth inhibition, root gravitropic response, and hyposensitivity to exogenous auxin. Fab1a and fab1b double mutant displays an abnormal vacuolar phenotype late in pollen development leading to inviable pollen (PubMed:19846542).3 Publications

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00004218701 – 17571-phosphatidylinositol-3-phosphate 5-kinase FAB1AAdd BLAST1757

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q0WUR5

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q0WUR5

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Ubiquitous with highest expression levels in pollen, seed, and senescent leaves.1 Publication

Gene expression databases

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q0WUR5 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q0WUR5 AT

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Component of the PI(3,5)P2 regulatory complex at least composed of ATG18, SAC/FIG4, FAB1 and VAC14.

By similarity

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
3702.AT4G33240.1

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q0WUR5

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1395 – 1719PIPKPROSITE-ProRule annotationAdd BLAST325

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili1014 – 1087Sequence analysisAdd BLAST74

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi209 – 213Poly-Asp5

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri36 – 102FYVE-typePROSITE-ProRule annotationAdd BLAST67

Keywords - Domaini

Coiled coil, Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0230 Eukaryota
COG0459 LUCA
COG5253 LUCA

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000241144

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q0WUR5

KEGG Orthology (KO)

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KOi
K00921

Database of Orthologous Groups

More...
OrthoDBi
227882at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q0WUR5

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.30.40.10, 1 hit
3.30.800.10, 1 hit
3.50.7.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR002423 Cpn60/TCP-1
IPR027409 GroEL-like_apical_dom_sf
IPR002498 PInositol-4-P-5-kinase_core
IPR027484 PInositol-4-P-5-kinase_N
IPR000306 Znf_FYVE
IPR017455 Znf_FYVE-rel
IPR011011 Znf_FYVE_PHD
IPR013083 Znf_RING/FYVE/PHD

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00118 Cpn60_TCP1, 1 hit
PF01363 FYVE, 1 hit
PF01504 PIP5K, 2 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00064 FYVE, 1 hit
SM00330 PIPKc, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF52029 SSF52029, 1 hit
SSF57903 SSF57903, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51455 PIPK, 1 hit
PS50178 ZF_FYVE, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 1 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoform i produced by alternative splicing. AlignAdd to basket

This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q0WUR5-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MDSQDHKAPG FVDIVKSWIP RKSESSNMSR DFWMPDQSCP VCYECDAQFT
60 70 80 90 100
VFNRRHHCRL CGRVFCAKCA ANSIPSPSDE TKDSHEEPER IRVCNYCYKQ
110 120 130 140 150
WEQGIVPPDN GASIISLHFS SSPSARSVAS TTSNSSNCTI DSTAGPSPRP
160 170 180 190 200
KMNPRASRRV SSNMDSEKSE QQNAKSRRSS DHYGHVLDSS DNQVEFFVNS
210 220 230 240 250
SGRSDGEADD DDDYQSDFAQ SYAQGNDYYG AINLDEVDHI YGSHEAHDVG
260 270 280 290 300
VKIEPNISGF PPDQDLDSLN TETIDKTRQQ ENGWNDVKEG SPPCEESFEP
310 320 330 340 350
EVVDFESDGL LWLPPEPENE EDEREAVLSD DDGDEGDRGD WGYLRPSNSF
360 370 380 390 400
NEKDFHSKDK SSGAMKNVVE GHFRALVAQL LEVDNLPMVN EGDEEGWLDI
410 420 430 440 450
ITSLSWEAAT LLKPDTSKSG GMDPGGYVKV KCIPCGRRSE SMVVKGVVCK
460 470 480 490 500
KNVAHRRMTS KIEKPRLLIL GGALEYQRIS NQLSSFDTLL QQEMDHLKMA
510 520 530 540 550
VAKIDSHNPD ILLVEKSVSR FAQEYLLAKD ISLVLNIKRS LLERISRCTG
560 570 580 590 600
AQIVPSIDQL TSPKLGYCDL FHVEKFVETH VSPCQVAKKM AKTLMFFDGC
610 620 630 640 650
PKPLGCTILL KGAHEDELKK VKHVIQYGVF AAYHLALETS FLADEGASIH
660 670 680 690 700
ELPLQTPITV ALPDKPSMVN RSISTIPGFT VSSAEKSPTT ELRGEPHKAN
710 720 730 740 750
GDLTGNFTSS KTHFQGKLDG NDRIDPSERL LHNLDTVYCK PPETITSKDD
760 770 780 790 800
GLVPTLESRQ LSFHVEEPSV QKDQWSVLSG ATEQVTDGGY TNDSAVIGNQ
810 820 830 840 850
NFNRQEQMES SKGDFHPSAS DHQSILVSLS TRCVWKGSVC ERAHLLRIKY
860 870 880 890 900
YGSFDKPLGR FLRDNLFDQD QCCPSCTMPA EAHIHCYTHR QGSLTISVKK
910 920 930 940 950
LPELLPGQRE GKIWMWHRCL KCPRINGFPP ATRRIVMSDA AWGLSFGKFL
960 970 980 990 1000
ELSFSNHAAA SRVANCGHSL HRDCLRFYGF GRMVACFRYA SINIYAVTLP
1010 1020 1030 1040 1050
PAKLYFNYEN QEWLQKESKE VIKKAEVLFN EVQEALSQIS AKTMGAGSKG
1060 1070 1080 1090 1100
STPNKIKLSL EELAGLLEQR KKEYKDSLQQ MLNVVKDGQP TIDILLINKL
1110 1120 1130 1140 1150
RRLIIFDSYA WDECLAGAAN MVRNNYLEAP KNSAPKVMGR NVSLEKLSDE
1160 1170 1180 1190 1200
KVKSIPTHVA ICNDSLLQDA DYETCLNQGK SFADTSGKFA IPEDVGSDRP
1210 1220 1230 1240 1250
PDCRMEFDPS EGGKDNFVES SQVVKPAHTE SQFQATDLSD TLDAAWIGEQ
1260 1270 1280 1290 1300
TTSENGIFRP PSRAASTNGT QIPDLRLLGS ESELNFKGGP TNDEHTTQVQ
1310 1320 1330 1340 1350
LPSPSFYYSL NKNYSLNSRK HIMAEDRPVY VSSYRELEWR SGARLLLPLG
1360 1370 1380 1390 1400
CNDLVLPVYD DEPTSIIAYA LTSSEYKAQM SGSDKSRDRL DSGGSFSLFD
1410 1420 1430 1440 1450
SVNLLSLNSL SDLSVDMSRS LSSADEQVSQ LLHSSLYLKD LHARISFTDE
1460 1470 1480 1490 1500
GPPGKVKYSV TCYYAKEFEA LRMICCPSET DFIRSLGRCR KWGAQGGKSN
1510 1520 1530 1540 1550
VFFAKSLDDR FIIKQVTKTE LESFIKFGPA YFKYLTESIS TKSPTSLAKI
1560 1570 1580 1590 1600
LGIYQVSSKH LKGGKEFKMD VLVMENLLFK RNFTRLYDLK GSTRARYNPD
1610 1620 1630 1640 1650
TSGSNTVLLD QNLVEAMPTS PIFVGSKAKR LLERAVWNDT SFLASIHVMD
1660 1670 1680 1690 1700
YSLLVGVDEE RNELVLGIID FMRQYTWDKH LETWVKTSGL LGGPKNSTPT
1710 1720 1730 1740 1750
VISPQQYKKR FRKAMTAYFL MVPDQWSPAA VVPSNSSSAE VKEEEEKDNP

QAVGNKS
Note: A number of isoforms are produced. According to EST sequences.
Length:1,757
Mass (Da):196,193
Last modified:September 5, 2006 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i0F7AF38EE610CD5A
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
F4JW01F4JW01_ARATH
1-phosphatidylinositol-3-phosphate ...
FAB1A At4g33240, F4I10.170, F4I10_170
1,753Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F4JW00F4JW00_ARATH
1-phosphatidylinositol-3-phosphate ...
FAB1A At4g33240, F4I10.170, F4I10_170
1,756Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A1P8B5L8A0A1P8B5L8_ARATH
1-phosphatidylinositol-3-phosphate ...
FAB1A At4g33240, F4I10.170, F4I10_170
1,754Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A1P8B5M2A0A1P8B5M2_ARATH
1-phosphatidylinositol-3-phosphate ...
FAB1A At4g33240, F4I10.170, F4I10_170
1,717Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti279Q → H in CAB36798 (PubMed:10617198).Curated1
Sequence conflicti279Q → H in CAB80041 (PubMed:10617198).Curated1
Sequence conflicti285N → T in CAB36798 (PubMed:10617198).Curated1
Sequence conflicti285N → T in CAB80041 (PubMed:10617198).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AL035525 Genomic DNA Translation: CAB36798.1
AL161583 Genomic DNA Translation: CAB80041.1
CP002687 Genomic DNA Translation: AEE86194.1
CP002687 Genomic DNA Translation: ANM66882.1
CP002687 Genomic DNA Translation: ANM66883.1
AK227081 mRNA Translation: BAE99133.1

Protein sequence database of the Protein Information Resource

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PIRi
T05204

NCBI Reference Sequences

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RefSeqi
NP_001320122.1, NM_001342205.1 [Q0WUR5-1]
NP_001328751.1, NM_001342208.1 [Q0WUR5-1]
NP_195050.6, NM_119478.7 [Q0WUR5-1]

Genome annotation databases

Ensembl plant genome annotation project

More...
EnsemblPlantsi
AT4G33240.1; AT4G33240.1; AT4G33240 [Q0WUR5-1]
AT4G33240.6; AT4G33240.6; AT4G33240 [Q0WUR5-1]
AT4G33240.7; AT4G33240.7; AT4G33240 [Q0WUR5-1]

Database of genes from NCBI RefSeq genomes

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GeneIDi
829460

Gramene; a comparative resource for plants

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Gramenei
AT4G33240.1; AT4G33240.1; AT4G33240 [Q0WUR5-1]
AT4G33240.6; AT4G33240.6; AT4G33240 [Q0WUR5-1]
AT4G33240.7; AT4G33240.7; AT4G33240 [Q0WUR5-1]

KEGG: Kyoto Encyclopedia of Genes and Genomes

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KEGGi
ath:AT4G33240

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL035525 Genomic DNA Translation: CAB36798.1
AL161583 Genomic DNA Translation: CAB80041.1
CP002687 Genomic DNA Translation: AEE86194.1
CP002687 Genomic DNA Translation: ANM66882.1
CP002687 Genomic DNA Translation: ANM66883.1
AK227081 mRNA Translation: BAE99133.1
PIRiT05204
RefSeqiNP_001320122.1, NM_001342205.1 [Q0WUR5-1]
NP_001328751.1, NM_001342208.1 [Q0WUR5-1]
NP_195050.6, NM_119478.7 [Q0WUR5-1]

3D structure databases

SMRiQ0WUR5
ModBaseiSearch...

Protein-protein interaction databases

STRINGi3702.AT4G33240.1

PTM databases

iPTMnetiQ0WUR5

Proteomic databases

PaxDbiQ0WUR5

Genome annotation databases

EnsemblPlantsiAT4G33240.1; AT4G33240.1; AT4G33240 [Q0WUR5-1]
AT4G33240.6; AT4G33240.6; AT4G33240 [Q0WUR5-1]
AT4G33240.7; AT4G33240.7; AT4G33240 [Q0WUR5-1]
GeneIDi829460
GrameneiAT4G33240.1; AT4G33240.1; AT4G33240 [Q0WUR5-1]
AT4G33240.6; AT4G33240.6; AT4G33240 [Q0WUR5-1]
AT4G33240.7; AT4G33240.7; AT4G33240 [Q0WUR5-1]
KEGGiath:AT4G33240

Organism-specific databases

AraportiAT4G33240
TAIRilocus:2125884 AT4G33240

Phylogenomic databases

eggNOGiKOG0230 Eukaryota
COG0459 LUCA
COG5253 LUCA
HOGENOMiHOG000241144
InParanoidiQ0WUR5
KOiK00921
OrthoDBi227882at2759
PhylomeDBiQ0WUR5

Enzyme and pathway databases

BioCyciARA:AT4G33240-MONOMER

Miscellaneous databases

Protein Ontology

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PROi
PR:Q0WUR5

Gene expression databases

ExpressionAtlasiQ0WUR5 baseline and differential
GenevisibleiQ0WUR5 AT

Family and domain databases

Gene3Di3.30.40.10, 1 hit
3.30.800.10, 1 hit
3.50.7.10, 1 hit
InterProiView protein in InterPro
IPR002423 Cpn60/TCP-1
IPR027409 GroEL-like_apical_dom_sf
IPR002498 PInositol-4-P-5-kinase_core
IPR027484 PInositol-4-P-5-kinase_N
IPR000306 Znf_FYVE
IPR017455 Znf_FYVE-rel
IPR011011 Znf_FYVE_PHD
IPR013083 Znf_RING/FYVE/PHD
PfamiView protein in Pfam
PF00118 Cpn60_TCP1, 1 hit
PF01363 FYVE, 1 hit
PF01504 PIP5K, 2 hits
SMARTiView protein in SMART
SM00064 FYVE, 1 hit
SM00330 PIPKc, 1 hit
SUPFAMiSSF52029 SSF52029, 1 hit
SSF57903 SSF57903, 1 hit
PROSITEiView protein in PROSITE
PS51455 PIPK, 1 hit
PS50178 ZF_FYVE, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiFAB1A_ARATH
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q0WUR5
Secondary accession number(s): Q9SMY5
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 3, 2013
Last sequence update: September 5, 2006
Last modified: October 16, 2019
This is version 111 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
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