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Entry version 95 (02 Jun 2021)
Sequence version 1 (05 Sep 2006)
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Protein

Probable alpha,alpha-trehalose-phosphate synthase [UDP-forming] 8

Gene

TPS8

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionGlycosyltransferase, Transferase

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...
BioCyci
ARA:AT1G70290-MONOMER

Protein family/group databases

Carbohydrate-Active enZymes

More...
CAZyi
GT20, Glycosyltransferase Family 20

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Probable alpha,alpha-trehalose-phosphate synthase [UDP-forming] 8 (EC:2.4.1.15)
Alternative name(s):
Trehalose-6-phosphate synthase 8
Short name:
AtTPS8
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:TPS8
Synonyms:TPS2, TPSC
Ordered Locus Names:At1g70290
ORF Names:F17O7.18
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiArabidopsis thaliana (Mouse-ear cress)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri3702 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliopsidaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000006548 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 1

Organism-specific databases

Arabidopsis Information Portal

More...
Araporti
AT1G70290

The Arabidopsis Information Resource

More...
TAIRi
locus:2016179, AT1G70290

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003248291 – 856Probable alpha,alpha-trehalose-phosphate synthase [UDP-forming] 8Add BLAST856

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei5PhosphoserineBy similarity1
Modified residuei32PhosphothreonineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q0WUI9

PRoteomics IDEntifications database

More...
PRIDEi
Q0WUI9

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
228333

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q0WUI9

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Expressed in leaves, roots, stems and flowers.1 Publication

Gene expression databases

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q0WUI9, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q0WUI9, AT

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
28585, 1 interactor

STRING: functional protein association networks

More...
STRINGi
3702.AT1G70290.1

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q0WUI9

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni57 – 541GlycosyltransferaseAdd BLAST485

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

In the N-terminal section; belongs to the glycosyltransferase 20 family.Curated
In the C-terminal section; belongs to the trehalose phosphatase family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1050, Eukaryota

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_002351_3_1_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q0WUI9

Identification of Orthologs from Complete Genome Data

More...
OMAi
DSVCRDG

Database of Orthologous Groups

More...
OrthoDBi
772297at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q0WUI9

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.40.50.1000, 2 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001830, Glyco_trans_20
IPR036412, HAD-like_sf
IPR006379, HAD-SF_hydro_IIB
IPR023214, HAD_sf
IPR003337, Trehalose_PPase

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00982, Glyco_transf_20, 1 hit
PF02358, Trehalose_PPase, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF56784, SSF56784, 1 hit

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR01484, HAD-SF-IIB, 1 hit
TIGR00685, T6PP, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q0WUI9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MVSRSCANFL DLSSWDLLDF PQTPRTLPRV MTVPGIITDV DGDTTSEVTS
60 70 80 90 100
TSGGSRERKI IVANMLPLQS KRDAETGKWC FNWDEDSLQL QLRDGFSSET
110 120 130 140 150
EFLYVGSLNV DIETNEQEEV SQKLLEEFNC VATFLSQELQ EMFYLGFCKH
160 170 180 190 200
QLWPLFHYML PMFPDHGDRF DRRLWQAYVS ANKIFSDRVM EVINPEDDYV
210 220 230 240 250
WIQDYHLMVL PTFLRKRFNR IKLGFFLHSP FPSSEIYRTL PVRDEILRGL
260 270 280 290 300
LNCDLIGFHT FDYARHFLSC CSRMLGLDYE SKRGHIGLDY FGRTVYIKIL
310 320 330 340 350
PVGVHMGRLE SVLSLDSTAA KTKEIQEQFK GKKLVLGIDD MDIFKGISLK
360 370 380 390 400
LIAMEHLFET YWHLKGKVVL VQIVNPARSS GKDVEEAKRE TYETARRINE
410 420 430 440 450
RYGTSDYKPI VLIDRLVPRS EKTAYYAAAD CCLVNAVRDG MNLVPYKYIV
460 470 480 490 500
CRQGTRSNKA VVDSSPRTST LVVSEFIGCS PSLSGAIRVN PWDVDAVAEA
510 520 530 540 550
VNSALKMSET EKQLRHEKHY HYISTHDVGY WAKSFMQDLE RACRDHYSKR
560 570 580 590 600
CWGIGFGLGF RVLSLSPSFR KLSVEHIVPV YRKTQRRAIF LDYDGTLVPE
610 620 630 640 650
SSIVQDPSNE VVSVLKALCE DPNNTVFIVS GRGRESLSNW LSPCENLGIA
660 670 680 690 700
AEHGYFIRWK SKDEWETCYS PTDTEWRSMV EPVMRSYMEA TDGTSIEFKE
710 720 730 740 750
SALVWHHQDA DPDFGSCQAK EMLDHLESVL ANEPVVVKRG QHIVEVKPQG
760 770 780 790 800
VSKGLAAEKV IREMVERGEP PEMVMCIGDD RSDEDMFESI LSTVTNPELL
810 820 830 840 850
VQPEVFACTV GRKPSKAKYF LDDEADVLKL LRGLGDSSSS LKPSSSHTQV

AFESIV
Length:856
Mass (Da):97,561
Last modified:September 5, 2006 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i7AA5627BF8307A7C
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A1P8AQ69A0A1P8AQ69_ARATH
Trehalose-6-phosphatase synthase S8
TPS8 ATTPS8, ATTPSC, At1g70290, F17O7.18, F17O7_18
818Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAC18810 differs from that shown. Reason: Erroneous initiation.Curated

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AC003671 Genomic DNA Translation: AAC18810.1 Different initiation.
CP002684 Genomic DNA Translation: AEE35042.1
AK227167 mRNA Translation: BAE99209.1
AF155150 mRNA Translation: AAO15311.1

Protein sequence database of the Protein Information Resource

More...
PIRi
T01494

NCBI Reference Sequences

More...
RefSeqi
NP_177186.2, NM_105697.4

Genome annotation databases

Ensembl plant genome annotation project

More...
EnsemblPlantsi
AT1G70290.1; AT1G70290.1; AT1G70290

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
843365

Gramene; a comparative resource for plants

More...
Gramenei
AT1G70290.1; AT1G70290.1; AT1G70290

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
ath:AT1G70290

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC003671 Genomic DNA Translation: AAC18810.1 Different initiation.
CP002684 Genomic DNA Translation: AEE35042.1
AK227167 mRNA Translation: BAE99209.1
AF155150 mRNA Translation: AAO15311.1
PIRiT01494
RefSeqiNP_177186.2, NM_105697.4

3D structure databases

SMRiQ0WUI9
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi28585, 1 interactor
STRINGi3702.AT1G70290.1

Protein family/group databases

CAZyiGT20, Glycosyltransferase Family 20

PTM databases

iPTMnetiQ0WUI9

Proteomic databases

PaxDbiQ0WUI9
PRIDEiQ0WUI9
ProteomicsDBi228333

Genome annotation databases

EnsemblPlantsiAT1G70290.1; AT1G70290.1; AT1G70290
GeneIDi843365
GrameneiAT1G70290.1; AT1G70290.1; AT1G70290
KEGGiath:AT1G70290

Organism-specific databases

AraportiAT1G70290
TAIRilocus:2016179, AT1G70290

Phylogenomic databases

eggNOGiKOG1050, Eukaryota
HOGENOMiCLU_002351_3_1_1
InParanoidiQ0WUI9
OMAiDSVCRDG
OrthoDBi772297at2759
PhylomeDBiQ0WUI9

Enzyme and pathway databases

BioCyciARA:AT1G70290-MONOMER

Miscellaneous databases

Protein Ontology

More...
PROi
PR:Q0WUI9

Gene expression databases

ExpressionAtlasiQ0WUI9, baseline and differential
GenevisibleiQ0WUI9, AT

Family and domain databases

Gene3Di3.40.50.1000, 2 hits
InterProiView protein in InterPro
IPR001830, Glyco_trans_20
IPR036412, HAD-like_sf
IPR006379, HAD-SF_hydro_IIB
IPR023214, HAD_sf
IPR003337, Trehalose_PPase
PfamiView protein in Pfam
PF00982, Glyco_transf_20, 1 hit
PF02358, Trehalose_PPase, 1 hit
SUPFAMiSSF56784, SSF56784, 1 hit
TIGRFAMsiTIGR01484, HAD-SF-IIB, 1 hit
TIGR00685, T6PP, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiTPS8_ARATH
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q0WUI9
Secondary accession number(s): O64608
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 18, 2008
Last sequence update: September 5, 2006
Last modified: June 2, 2021
This is version 95 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families
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