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Protein
Submitted name:

TNS1 protein

Gene

TNS1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Enzyme and pathway databases

SignaLinkiQ0VG54

Names & Taxonomyi

Protein namesi
Submitted name:
TNS1 proteinImported
Gene namesi
Name:TNS1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

PTM / Processingi

Proteomic databases

PeptideAtlasiQ0VG54
PRIDEiQ0VG54

Structurei

3D structure databases

ProteinModelPortaliQ0VG54
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini4 – 176Phosphatase tensin-typeInterPro annotationAdd BLAST173
Domaini181 – 307C2 tensin-typeInterPro annotationAdd BLAST127
Domaini1441 – 1550SH2InterPro annotationAdd BLAST110

Keywords - Domaini

SH2 domainPROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG1930 Eukaryota
KOG2283 Eukaryota
COG2453 LUCA
HOVERGENiHBG060186

Family and domain databases

CDDicd01213 PTB_tensin, 1 hit
cd09927 SH2_Tensin_like, 1 hit
Gene3Di2.30.29.30, 1 hit
3.30.505.10, 1 hit
3.90.190.10, 1 hit
InterProiView protein in InterPro
IPR011993 PH-like_dom_sf
IPR029021 Prot-tyrosine_phosphatase-like
IPR013625 PTB
IPR006020 PTB/PI_dom
IPR000980 SH2
IPR036860 SH2_dom_sf
IPR014020 Tensin_C2-dom
IPR035012 Tensin_like_SH2
IPR029023 Tensin_phosphatase
IPR033929 Tensin_PTB
IPR003595 Tyr_Pase_cat
PfamiView protein in Pfam
PF08416 PTB, 1 hit
PF10409 PTEN_C2, 1 hit
PF00017 SH2, 1 hit
SMARTiView protein in SMART
SM00462 PTB, 1 hit
SM01326 PTEN_C2, 1 hit
SM00404 PTPc_motif, 1 hit
SM00252 SH2, 1 hit
SUPFAMiSSF52799 SSF52799, 1 hit
SSF55550 SSF55550, 1 hit
PROSITEiView protein in PROSITE
PS51182 C2_TENSIN, 1 hit
PS51181 PPASE_TENSIN, 1 hit
PS50001 SH2, 1 hit

Sequencei

Sequence statusi: Complete.

Q0VG54-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSVSRTMEDS CELDLVYVTE RIIAVSFPST ANEENFRSNL REVAQMLKSK
60 70 80 90 100
HGGNYLLFNL SERRPDITKL HAKVLEFGWP DLHTPALEKI CSICKAMDTW
110 120 130 140 150
LNADPHNVVV LHNKGNRGRI GVVIAAYMHY SNISASADQA LDRFAMKRFY
160 170 180 190 200
EDKIVPIGQP SQRRYVHYFS GLLSGSIKMN NKPLFLHHVI MHGIPNFESK
210 220 230 240 250
GGCRPFLRIY QAMQPVYTSG IYNIPGDSQT SVCITIEPGL LLKGDILLKC
260 270 280 290 300
YHKKFRSPAR DVIFRVQFHT CAIHDLGVVF GKEDLDDAFK DDRFPEYGKV
310 320 330 340 350
EFVFSYGPEK IQGMEHLENG PSVSVDYNTS DPLIRWDSYD NFSGHRDDGM
360 370 380 390 400
EEVVGHTQGP LDGSLYAKVK KKDSLHGSTG AVNATRPTLS ATPNHVEHTL
410 420 430 440 450
SVSSDSGNST ASTKTDKTDE PVPGASSATA ALSPQEKREL DRLLSGFGLE
460 470 480 490 500
REKQGAMYHT QHLRSRPAGG SAVPSSGRHV VPAQVHVNGG ALASERETDI
510 520 530 540 550
LDDELPNQDG HSAGSMGTLS SLDGVTNTSE GGYPEALSPL TNGLDKSYPM
560 570 580 590 600
EPMVNGGGYP YESASRAGPA HAGHTAPMRP SYSAQEGLAG YQREGPHPAW
610 620 630 640 650
PQPVTTSHYA HDPSGMFRSQ SFSEAEPQLP PAPVRGGSSR EAVQRGLNSW
660 670 680 690 700
QQQQQQQQPR PPPRQQERAH LESLVASRPS PQPLAETPIP SLPEFPRAAS
710 720 730 740 750
QQEIEQSIET LNMLMLDLEP ASAAAPLHKS QSVPGAWPGA SPLSSQPLSG
760 770 780 790 800
SSRQSHPLTQ SRSGYIPSGH SLGTPEPAPR ASLESVPPGR SYSPYDYQPC
810 820 830 840 850
LAGPNQDFHS KSPASSSLPA FLPTTHSPPG PQQPPASLPG LTAQPLLSPK
860 870 880 890 900
EATSDPSRTP EEEPLNLEGL VAHRVAGVQA REKQPAEPPA PLRRRAASDG
910 920 930 940 950
QYENQSPEAT SPRSPGVRSP VQCVSPELAL TIALNPGGRP KEPHLHSYKE
960 970 980 990 1000
AFEEMEGTSP SSPPPSGVRS PPGLAKTPLS ALGLKPHNPA DILLHPTGEP
1010 1020 1030 1040 1050
RSYVESVART AVAGPRAQDS EPKSFSAPAT QAYGHEIPLR NGTLGGSFVS
1060 1070 1080 1090 1100
PSPLSTSSPI LSADSTSVGS FPSGESSDQG PRTPTQPLLE SGFRSGSLGQ
1110 1120 1130 1140 1150
PSPSAQRNYQ SSSPLPTVGS SYSSPDYSLQ HFSSSPESQA RAQFSVAGVH
1160 1170 1180 1190 1200
TVPGSPQARH RTVGTNTPPS PGFGRRAINS SMAAPSSPSL SHHQMMGPPG
1210 1220 1230 1240 1250
TGFHGSTVSS PQSSAATTPG SPSLCRHPAG VYQVSGLHNK VATTPGSPSL
1260 1270 1280 1290 1300
GRHPGAHQGN LASGLHSNAI ASPGSPSLGR HLGGSGSVVP GSPCLDRHVA
1310 1320 1330 1340 1350
YGGYSTPEDR RPTLSRQSSA SGYQAPSTPS FPVSPAYYPG LSSPATSPSP
1360 1370 1380 1390 1400
DSAAFRQGSP TPALPEKRRM SVGDRAGSLP NYATINGKVS SPVASGMSSP
1410 1420 1430 1440 1450
SGGSTVSFSH TLPDFSKYSM PDNSPETRAK VKFVQDTSKY WYKPEISREQ
1460 1470 1480 1490 1500
AIALLKDQEP GAFIIRDSHS FRGAYGLAMK VSSPPPTIMQ QNKKGDMTHE
1510 1520 1530 1540 1550
LVRHFLIETG PRGVKLKGCP NEPNFGSLSA LVYQHSIIPL ALPCKLVIPN
1560 1570 1580 1590 1600
RDPTDESKDS SGPANSTADL LKQGAACNVL FINSVDMESL TGPQAISKAT
1610 1620 1630 1640 1650
SETLAADPTP AATIVHFKVS AQGITLTDNQ RKLFFRRHYP LNTVTFCDLD
1660 1670 1680 1690 1700
PQERKWMKTE GGAPAKLFGF VARKQGSTTD NACHLFAELD PNQPASAIVN
1710
FVSKVMLNAG QKR
Length:1,713
Mass (Da):183,069
Last modified:September 5, 2006 - v1
Checksum:iC3622C7A4F9A5CD9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC116188 mRNA Translation: AAI16189.1
RefSeqiNP_001294951.1, NM_001308022.1
NP_001294952.1, NM_001308023.1
UniGeneiHs.471381

Genome annotation databases

GeneIDi7145

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC116188 mRNA Translation: AAI16189.1
RefSeqiNP_001294951.1, NM_001308022.1
NP_001294952.1, NM_001308023.1
UniGeneiHs.471381

3D structure databases

ProteinModelPortaliQ0VG54
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PeptideAtlasiQ0VG54
PRIDEiQ0VG54

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi7145

Organism-specific databases

CTDi7145

Phylogenomic databases

eggNOGiKOG1930 Eukaryota
KOG2283 Eukaryota
COG2453 LUCA
HOVERGENiHBG060186

Enzyme and pathway databases

SignaLinkiQ0VG54

Miscellaneous databases

ChiTaRSiTNS1 human
GenomeRNAii7145

Family and domain databases

CDDicd01213 PTB_tensin, 1 hit
cd09927 SH2_Tensin_like, 1 hit
Gene3Di2.30.29.30, 1 hit
3.30.505.10, 1 hit
3.90.190.10, 1 hit
InterProiView protein in InterPro
IPR011993 PH-like_dom_sf
IPR029021 Prot-tyrosine_phosphatase-like
IPR013625 PTB
IPR006020 PTB/PI_dom
IPR000980 SH2
IPR036860 SH2_dom_sf
IPR014020 Tensin_C2-dom
IPR035012 Tensin_like_SH2
IPR029023 Tensin_phosphatase
IPR033929 Tensin_PTB
IPR003595 Tyr_Pase_cat
PfamiView protein in Pfam
PF08416 PTB, 1 hit
PF10409 PTEN_C2, 1 hit
PF00017 SH2, 1 hit
SMARTiView protein in SMART
SM00462 PTB, 1 hit
SM01326 PTEN_C2, 1 hit
SM00404 PTPc_motif, 1 hit
SM00252 SH2, 1 hit
SUPFAMiSSF52799 SSF52799, 1 hit
SSF55550 SSF55550, 1 hit
PROSITEiView protein in PROSITE
PS51182 C2_TENSIN, 1 hit
PS51181 PPASE_TENSIN, 1 hit
PS50001 SH2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiQ0VG54_HUMAN
AccessioniPrimary (citable) accession number: Q0VG54
Entry historyiIntegrated into UniProtKB/TrEMBL: September 5, 2006
Last sequence update: September 5, 2006
Last modified: March 28, 2018
This is version 72 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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