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Protein

Palmitoyltransferase

Gene

Zdhhc17

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Catalytic activityi

Palmitoyl-CoA + [protein]-L-cysteine = [protein]-S-palmitoyl-L-cysteine + CoA.UniRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionAcyltransferaseUniRule annotationSAAS annotation, Transferase

Names & Taxonomyi

Protein namesi
Recommended name:
PalmitoyltransferaseUniRule annotation (EC:2.3.1.225UniRule annotation)
Gene namesi
Name:Zdhhc17Imported
ORF Names:mCG_122237Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:2445110 Zdhhc17

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei295 – 311HelicalUniRule annotationAdd BLAST17
Transmembranei317 – 335HelicalUniRule annotationAdd BLAST19
Transmembranei347 – 369HelicalUniRule annotationAdd BLAST23
Transmembranei375 – 393HelicalUniRule annotationAdd BLAST19
Transmembranei475 – 496HelicalUniRule annotationAdd BLAST22
Transmembranei529 – 551HelicalUniRule annotationAdd BLAST23

Keywords - Cellular componenti

Membrane

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini54 – 267ANK_REP_REGIONInterPro annotationAdd BLAST214
Repeati79 – 111ANKPROSITE-ProRule annotationAdd BLAST33
Repeati113 – 145ANKPROSITE-ProRule annotationAdd BLAST33
Repeati146 – 178ANKPROSITE-ProRule annotationAdd BLAST33
Repeati179 – 212ANKPROSITE-ProRule annotationAdd BLAST34
Repeati214 – 246ANKPROSITE-ProRule annotationAdd BLAST33

Domaini

The DHHC domain is required for palmitoyltransferase activity.UniRule annotation

Sequence similaritiesi

Belongs to the DHHC palmitoyltransferase family.UniRule annotationSAAS annotation

Keywords - Domaini

ANK repeatPROSITE-ProRule annotation, Transmembrane, Transmembrane helixUniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG0509 Eukaryota
COG0666 LUCA
COG5273 LUCA
HOVERGENiHBG051907

Family and domain databases

CDDicd00204 ANK, 2 hits
Gene3Di1.25.40.20, 1 hit
InterProiView protein in InterPro
IPR002110 Ankyrin_rpt
IPR020683 Ankyrin_rpt-contain_dom
IPR036770 Ankyrin_rpt-contain_sf
IPR001594 Palmitoyltrfase_DHHC
IPR030289 ZDHHC17
PANTHERiPTHR24161:SF18 PTHR24161:SF18, 1 hit
PfamiView protein in Pfam
PF12796 Ank_2, 2 hits
PF01529 DHHC, 1 hit
PRINTSiPR01415 ANKYRIN
SMARTiView protein in SMART
SM00248 ANK, 5 hits
SUPFAMiSSF48403 SSF48403, 1 hit
PROSITEiView protein in PROSITE
PS50297 ANK_REP_REGION, 1 hit
PS50088 ANK_REPEAT, 5 hits

Sequencei

Sequence statusi: Complete.

Q0VFY6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MADGPDEYET ETGCVPLLHP EEIKPQSHYN HGYGEPLGRK THIDDYSTWD
60 70 80 90 100
IVKATQYGIY ERCRELVEAG YDVRQPDKEN VTLLHWAAIN NRIDLVKYYI
110 120 130 140 150
SKGAIVDQLG GDLNSTPLHW ATRQGHLSMV VQLMKYGADP SLIDGEGCSC
160 170 180 190 200
IHLAAQFGHT SIVAYLIAKG QDVDMMDQNG MTPLMWAAYR THSVDPTRLL
210 220 230 240 250
LTFNVSVNLG DKYHKNTALH WAVLAGNTTV ISLLLEAGGN VDAQNVKGES
260 270 280 290 300
ALDLAKQRKN VWMINHLQEA RQAKGYDNPS FLRKLKADKE FRQKVMLGTP
310 320 330 340 350
FLVIWLVGFI ADLDIDSWLI KGLMYGGVWA TVQFLSKSFF DHSMHSALPL
360 370 380 390 400
GIYLATKFWM YVTWFFWFWN DLNFLFIHLP FLANSVALFY NFGKSWKSDP
410 420 430 440 450
GIIKATEEQK KKTIVELAET GSLDLSIFCS TCLIRKPVRS KHCGVCNRCI
460 470 480 490 500
AKFDHHCPWV GNCVGAGNHR YFMGYLFFLL FMICWMIYGC VSYWGLHCET
510 520 530 540 550
TYTKDGFWTY ITQIATCSPW MFWMFLNSVF HFLWVAVLLM CQLYQITCLG
560 570 580 590 600
ITTNERMNAR RYKHFKVTTT SIESPFNHGC VRNIIDFFEF RCCGLFRPVI
610 620
VDWTRQYTIE YDQISGSGYQ LV
Length:622
Mass (Da):71,399
Last modified:September 5, 2006 - v1
Checksum:i5E60AAF37874387E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC117788 mRNA Translation: AAI17789.1
BC117789 mRNA Translation: AAI17790.1
CH466539 Genomic DNA Translation: EDL21720.1
UniGeneiMm.339281

Similar proteinsi

Entry informationi

Entry nameiQ0VFY6_MOUSE
AccessioniPrimary (citable) accession number: Q0VFY6
Entry historyiIntegrated into UniProtKB/TrEMBL: September 5, 2006
Last sequence update: September 5, 2006
Last modified: March 28, 2018
This is version 97 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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