UniProtKB - Q0VDI3 (TM267_HUMAN)
Protein
Transmembrane protein 267
Gene
TMEM267
Organism
Homo sapiens (Human)
Status
Names & Taxonomyi
Protein namesi | Recommended name: Transmembrane protein 267Imported |
Gene namesi | |
Organismi | Homo sapiens (Human) |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:26139, TMEM267 |
neXtProti | NX_Q0VDI3 |
VEuPathDBi | HostDB:ENSG00000151881.14 |
Subcellular locationi
Other locations
- Membrane Curated; Multi-pass membrane protein Curated
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 77 – 97 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 114 – 134 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 178 – 198 | HelicalSequence analysisAdd BLAST | 21 |
Keywords - Cellular componenti
MembranePathology & Biotechi
Organism-specific databases
DisGeNETi | 64417 |
OpenTargetsi | ENSG00000151881 |
PharmGKBi | PA162380004 |
Miscellaneous databases
Pharosi | Q0VDI3, Tdark |
Genetic variation databases
BioMutai | TMEM267 |
DMDMi | 121940485 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000281921 | 1 – 215 | Transmembrane protein 267Add BLAST | 215 |
Proteomic databases
EPDi | Q0VDI3 |
jPOSTi | Q0VDI3 |
MassIVEi | Q0VDI3 |
MaxQBi | Q0VDI3 |
PaxDbi | Q0VDI3 |
PeptideAtlasi | Q0VDI3 |
PRIDEi | Q0VDI3 |
ProteomicsDBi | 58829 |
Expressioni
Gene expression databases
Bgeei | ENSG00000151881, Expressed in thyroid gland and 201 other tissues |
ExpressionAtlasi | Q0VDI3, baseline and differential |
Genevisiblei | Q0VDI3, HS |
Organism-specific databases
HPAi | ENSG00000151881, Low tissue specificity |
Interactioni
Binary interactionsi
Hide detailsQ0VDI3
Protein-protein interaction databases
BioGRIDi | 122166, 12 interactors |
IntActi | Q0VDI3, 9 interactors |
STRINGi | 9606.ENSP00000426067 |
Miscellaneous databases
RNActi | Q0VDI3, protein |
Family & Domainsi
Keywords - Domaini
Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | ENOG502QQ1U, Eukaryota |
GeneTreei | ENSGT00390000003050 |
InParanoidi | Q0VDI3 |
OMAi | LCSVLMY |
OrthoDBi | 1326580at2759 |
PhylomeDBi | Q0VDI3 |
TreeFami | TF323520 |
Family and domain databases
InterProi | View protein in InterPro IPR026572, TMEM267 |
PANTHERi | PTHR13628, PTHR13628, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All
Q0VDI3-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MASETEKTHA LLQTCSTESL ISSLGLGAFC LVADRLLQFS TIQQNDWLRA
60 70 80 90 100
LSDNAVHCVI GMWSWAVVTG IKKKTDFGEI ILAGFLASVI DVDHFFLAGS
110 120 130 140 150
MSLKAALTLP RRPFLHCSTV IPVVVLTLKF TMHLFKLKDS WCFLPWMLFI
160 170 180 190 200
SWTSHHIRDG IRHGLWICPF GKTSPLPFWL YVIITSSLPH ICSFVMYLTG
210
TRQMMSSKHG VRIDV
Computationally mapped potential isoform sequencesi
There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketE9PBX6 | E9PBX6_HUMAN | Transmembrane protein 267 | TMEM267 | 113 | Annotation score: | ||
D6RAV6 | D6RAV6_HUMAN | Transmembrane protein 267 | TMEM267 | 176 | Annotation score: |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 86 | L → F in BAB15108 (PubMed:14702039).Curated | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AK025310 mRNA Translation: BAB15108.1 AK315466 mRNA Translation: BAG37853.1 CH471119 Genomic DNA Translation: EAW56061.1 BC063832 mRNA Translation: AAH63832.1 BC013351 mRNA Translation: AAH13351.1 BC119658 mRNA Translation: AAI19659.1 BC119659 mRNA Translation: AAI19660.1 |
CCDSi | CCDS3945.1 |
RefSeqi | NP_071928.2, NM_022483.4 XP_005248390.1, XM_005248333.4 XP_005248392.1, XM_005248335.3 XP_006714549.1, XM_006714486.3 XP_011512376.1, XM_011514074.2 XP_011512377.1, XM_011514075.2 |
Genome annotation databases
Ensembli | ENST00000397080; ENSP00000380270; ENSG00000151881 ENST00000500337; ENSP00000426067; ENSG00000151881 ENST00000512085; ENSP00000422881; ENSG00000151881 |
GeneIDi | 64417 |
KEGGi | hsa:64417 |
UCSCi | uc003jnv.5, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AK025310 mRNA Translation: BAB15108.1 AK315466 mRNA Translation: BAG37853.1 CH471119 Genomic DNA Translation: EAW56061.1 BC063832 mRNA Translation: AAH63832.1 BC013351 mRNA Translation: AAH13351.1 BC119658 mRNA Translation: AAI19659.1 BC119659 mRNA Translation: AAI19660.1 |
CCDSi | CCDS3945.1 |
RefSeqi | NP_071928.2, NM_022483.4 XP_005248390.1, XM_005248333.4 XP_005248392.1, XM_005248335.3 XP_006714549.1, XM_006714486.3 XP_011512376.1, XM_011514074.2 XP_011512377.1, XM_011514075.2 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
BioGRIDi | 122166, 12 interactors |
IntActi | Q0VDI3, 9 interactors |
STRINGi | 9606.ENSP00000426067 |
Genetic variation databases
BioMutai | TMEM267 |
DMDMi | 121940485 |
Proteomic databases
EPDi | Q0VDI3 |
jPOSTi | Q0VDI3 |
MassIVEi | Q0VDI3 |
MaxQBi | Q0VDI3 |
PaxDbi | Q0VDI3 |
PeptideAtlasi | Q0VDI3 |
PRIDEi | Q0VDI3 |
ProteomicsDBi | 58829 |
Protocols and materials databases
Antibodypediai | 67211, 28 antibodies |
Genome annotation databases
Ensembli | ENST00000397080; ENSP00000380270; ENSG00000151881 ENST00000500337; ENSP00000426067; ENSG00000151881 ENST00000512085; ENSP00000422881; ENSG00000151881 |
GeneIDi | 64417 |
KEGGi | hsa:64417 |
UCSCi | uc003jnv.5, human |
Organism-specific databases
CTDi | 64417 |
DisGeNETi | 64417 |
GeneCardsi | TMEM267 |
HGNCi | HGNC:26139, TMEM267 |
HPAi | ENSG00000151881, Low tissue specificity |
neXtProti | NX_Q0VDI3 |
OpenTargetsi | ENSG00000151881 |
PharmGKBi | PA162380004 |
VEuPathDBi | HostDB:ENSG00000151881.14 |
GenAtlasi | Search... |
Phylogenomic databases
eggNOGi | ENOG502QQ1U, Eukaryota |
GeneTreei | ENSGT00390000003050 |
InParanoidi | Q0VDI3 |
OMAi | LCSVLMY |
OrthoDBi | 1326580at2759 |
PhylomeDBi | Q0VDI3 |
TreeFami | TF323520 |
Enzyme and pathway databases
PathwayCommonsi | Q0VDI3 |
Miscellaneous databases
BioGRID-ORCSi | 64417, 3 hits in 874 CRISPR screens |
ChiTaRSi | TMEM267, human |
GenomeRNAii | 64417 |
Pharosi | Q0VDI3, Tdark |
PROi | PR:Q0VDI3 |
RNActi | Q0VDI3, protein |
Gene expression databases
Bgeei | ENSG00000151881, Expressed in thyroid gland and 201 other tissues |
ExpressionAtlasi | Q0VDI3, baseline and differential |
Genevisiblei | Q0VDI3, HS |
Family and domain databases
InterProi | View protein in InterPro IPR026572, TMEM267 |
PANTHERi | PTHR13628, PTHR13628, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | TM267_HUMAN | |
Accessioni | Q0VDI3Primary (citable) accession number: Q0VDI3 Secondary accession number(s): B2RDA6, Q9H6Z2 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | April 3, 2007 |
Last sequence update: | September 5, 2006 | |
Last modified: | February 10, 2021 | |
This is version 101 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Human chromosome 5
Human chromosome 5: entries, gene names and cross-references to MIM