UniProtKB - Q0VDE8 (ADIG_HUMAN)
Protein
Adipogenin
Gene
ADIG
Organism
Homo sapiens (Human)
Status
Functioni
Plays a role in stimulating adipocyte differentiation and development.By similarity
GO - Biological processi
- brown fat cell differentiation Source: HGNC-UCL
- positive regulation of fat cell differentiation Source: HGNC-UCL
- spermatogenesis Source: Ensembl
- white fat cell differentiation Source: HGNC-UCL
Enzyme and pathway databases
PathwayCommonsi | Q0VDE8 |
Names & Taxonomyi
Protein namesi | Recommended name: Adipogenin |
Gene namesi | Name:ADIGImported |
Organismi | Homo sapiens (Human) |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
EuPathDBi | HostDB:ENSG00000182035.11 |
HGNCi | HGNC:28606, ADIG |
MIMi | 611396, gene |
neXtProti | NX_Q0VDE8 |
Subcellular locationi
Nucleus
- Nucleus By similarity
Other locations
- Membrane Sequence analysis; Single-pass membrane protein Sequence analysis
Nucleus
- nucleus Source: HGNC-UCL
Other locations
- cytoplasm Source: HGNC-UCL
- integral component of membrane Source: UniProtKB-KW
- lipid droplet Source: GO_Central
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 14 – 34 | HelicalSequence analysisAdd BLAST | 21 |
Keywords - Cellular componenti
Membrane, NucleusPathology & Biotechi
Organism-specific databases
DisGeNETi | 149685 |
OpenTargetsi | ENSG00000182035 |
PharmGKBi | PA162375689 |
Miscellaneous databases
Pharosi | Q0VDE8, Tdark |
Polymorphism and mutation databases
BioMutai | ADIG |
DMDMi | 156630981 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000296375 | 1 – 80 | AdipogeninAdd BLAST | 80 |
Proteomic databases
MassIVEi | Q0VDE8 |
PaxDbi | Q0VDE8 |
PeptideAtlasi | Q0VDE8 |
PRIDEi | Q0VDE8 |
ProteomicsDBi | 58824 |
PTM databases
PhosphoSitePlusi | Q0VDE8 |
Expressioni
Gene expression databases
Bgeei | ENSG00000182035, Expressed in right testis and 109 other tissues |
ExpressionAtlasi | Q0VDE8, baseline and differential |
Genevisiblei | Q0VDE8, HS |
Organism-specific databases
HPAi | ENSG00000182035, Tissue enriched (testis) |
Interactioni
Protein-protein interaction databases
STRINGi | 9606.ENSP00000440331 |
Miscellaneous databases
RNActi | Q0VDE8, protein |
Family & Domainsi
Sequence similaritiesi
Belongs to the adipogenin family.Curated
Keywords - Domaini
Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | ENOG502SXJP, Eukaryota |
GeneTreei | ENSGT00390000018723 |
HOGENOMi | CLU_2605436_0_0_1 |
InParanoidi | Q0VDE8 |
OMAi | SDLCFNW |
OrthoDBi | 1564414at2759 |
PhylomeDBi | Q0VDE8 |
Family and domain databases
InterProi | View protein in InterPro IPR027938, Adipogenin |
PANTHERi | PTHR38499, PTHR38499, 1 hit |
Pfami | View protein in Pfam PF15202, Adipogenin, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All
Q0VDE8-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MKYPLMPLVN DLTFSFLVFW FCLPVGLLLL LIIWLRFLLS QDSEENDSSV
60 70 80
CLDWEPWSKG PAEFCWKGTL HGQEKERPCW
Computationally mapped potential isoform sequencesi
There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketH0Y829 | H0Y829_HUMAN | Adipogenin | ADIG | 197 | Annotation score: | ||
A2A2E7 | A2A2E7_HUMAN | Adipogenin | ADIG | 59 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL035419 Genomic DNA No translation available. BC119704 mRNA Translation: AAI19705.1 BC119705 mRNA Translation: AAI19706.1 |
CCDSi | CCDS54461.1 |
RefSeqi | NP_001018092.1, NM_001018082.2 |
Genome annotation databases
Ensembli | ENST00000470147; ENSP00000434385; ENSG00000182035 ENST00000537425; ENSP00000440331; ENSG00000182035 |
GeneIDi | 149685 |
KEGGi | hsa:149685 |
UCSCi | uc002xjb.1, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL035419 Genomic DNA No translation available. BC119704 mRNA Translation: AAI19705.1 BC119705 mRNA Translation: AAI19706.1 |
CCDSi | CCDS54461.1 |
RefSeqi | NP_001018092.1, NM_001018082.2 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 9606.ENSP00000440331 |
PTM databases
PhosphoSitePlusi | Q0VDE8 |
Polymorphism and mutation databases
BioMutai | ADIG |
DMDMi | 156630981 |
Proteomic databases
MassIVEi | Q0VDE8 |
PaxDbi | Q0VDE8 |
PeptideAtlasi | Q0VDE8 |
PRIDEi | Q0VDE8 |
ProteomicsDBi | 58824 |
Protocols and materials databases
Antibodypediai | 51583, 11 antibodies |
DNASUi | 149685 |
Genome annotation databases
Ensembli | ENST00000470147; ENSP00000434385; ENSG00000182035 ENST00000537425; ENSP00000440331; ENSG00000182035 |
GeneIDi | 149685 |
KEGGi | hsa:149685 |
UCSCi | uc002xjb.1, human |
Organism-specific databases
CTDi | 149685 |
DisGeNETi | 149685 |
EuPathDBi | HostDB:ENSG00000182035.11 |
GeneCardsi | ADIG |
HGNCi | HGNC:28606, ADIG |
HPAi | ENSG00000182035, Tissue enriched (testis) |
MIMi | 611396, gene |
neXtProti | NX_Q0VDE8 |
OpenTargetsi | ENSG00000182035 |
PharmGKBi | PA162375689 |
GenAtlasi | Search... |
Phylogenomic databases
eggNOGi | ENOG502SXJP, Eukaryota |
GeneTreei | ENSGT00390000018723 |
HOGENOMi | CLU_2605436_0_0_1 |
InParanoidi | Q0VDE8 |
OMAi | SDLCFNW |
OrthoDBi | 1564414at2759 |
PhylomeDBi | Q0VDE8 |
Enzyme and pathway databases
PathwayCommonsi | Q0VDE8 |
Miscellaneous databases
BioGRID-ORCSi | 149685, 4 hits in 838 CRISPR screens |
GenomeRNAii | 149685 |
Pharosi | Q0VDE8, Tdark |
PROi | PR:Q0VDE8 |
RNActi | Q0VDE8, protein |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSG00000182035, Expressed in right testis and 109 other tissues |
ExpressionAtlasi | Q0VDE8, baseline and differential |
Genevisiblei | Q0VDE8, HS |
Family and domain databases
InterProi | View protein in InterPro IPR027938, Adipogenin |
PANTHERi | PTHR38499, PTHR38499, 1 hit |
Pfami | View protein in Pfam PF15202, Adipogenin, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | ADIG_HUMAN | |
Accessioni | Q0VDE8Primary (citable) accession number: Q0VDE8 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | July 24, 2007 |
Last sequence update: | February 20, 2007 | |
Last modified: | December 2, 2020 | |
This is version 81 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot - SIMILARITY comments
Index of protein domains and families - Human chromosome 20
Human chromosome 20: entries, gene names and cross-references to MIM