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UniProtKB - Q0VDC6 (Q0VDC6_HUMAN)
Protein
Peptidylprolyl isomerase
Gene
FKBP1A
Organism
Homo sapiens (Human)
Status
Functioni
Catalytic activityi
- EC:5.2.1.8PROSITE-ProRule annotation
GO - Molecular functioni
- peptidyl-prolyl cis-trans isomerase activity Source: UniProtKB-KW
Keywordsi
Molecular function | Isomerase, RotamasePROSITE-ProRule annotation |
Names & Taxonomyi
Protein namesi | Recommended name: Peptidylprolyl isomerasePROSITE-ProRule annotation (EC:5.2.1.8PROSITE-ProRule annotation) |
Gene namesi | Name:FKBP1AImported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Interactioni
Binary interactionsi
Q0VDC6
Protein-protein interaction databases
IntActi | Q0VDC6, 68 interactors |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 57 – 145 | PPIase FKBP-typeInterPro annotationAdd BLAST | 89 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 35 | DisorderedSequence analysisAdd BLAST | 35 |
Family and domain databases
Gene3Di | 3.10.50.40, 1 hit |
InterProi | View protein in InterPro IPR046357, PPIase_dom_sf IPR001179, PPIase_FKBP_dom |
Pfami | View protein in Pfam PF00254, FKBP_C, 1 hit |
PROSITEi | View protein in PROSITE PS50059, FKBP_PPIASE, 1 hit |
i Sequence
Sequence statusi: Complete.
Q0VDC6-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MGRQRAEGLG RAVEPPPGRC WSTPPVAPPA RSASAAAMGV QVETISPGDG
60 70 80 90 100
RTFPKRGQTC VVHYTGMLED GKKFDSSRDR NKPFKFMLGK QEVIRGWEEG
110 120 130 140
VAQMSVGQRA KLTISPDYAY GATGHPGIIP PHATLVFDVE LLKLE
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BC119732 mRNA Translation: AAI19733.1 |
RefSeqi | NP_000792.1, NM_000801.4 |
Genome annotation databases
GeneIDi | 2280 |
KEGGi | hsa:2280 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BC119732 mRNA Translation: AAI19733.1 |
RefSeqi | NP_000792.1, NM_000801.4 |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
7EPD | electron microscopy | 3.90 | A | 39-145 | [»] | |
SMRi | Q0VDC6 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Protein-protein interaction databases
IntActi | Q0VDC6, 68 interactors |
Proteomic databases
MaxQBi | Q0VDC6 |
PeptideAtlasi | Q0VDC6 |
Protocols and materials databases
DNASUi | 2280 |
Genome annotation databases
GeneIDi | 2280 |
KEGGi | hsa:2280 |
Organism-specific databases
CTDi | 2280 |
PharmGKBi | PA28153 |
Miscellaneous databases
BioGRID-ORCSi | 2280, 243 hits in 1007 CRISPR screens |
ChiTaRSi | FKBP1A, human |
GenomeRNAii | 2280 |
Gene expression databases
Genevisiblei | Q0VDC6, HS |
Family and domain databases
Gene3Di | 3.10.50.40, 1 hit |
InterProi | View protein in InterPro IPR046357, PPIase_dom_sf IPR001179, PPIase_FKBP_dom |
Pfami | View protein in Pfam PF00254, FKBP_C, 1 hit |
PROSITEi | View protein in PROSITE PS50059, FKBP_PPIASE, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | Q0VDC6_HUMAN | |
Accessioni | Q0VDC6Primary (citable) accession number: Q0VDC6 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | September 5, 2006 |
Last sequence update: | September 5, 2006 | |
Last modified: | May 25, 2022 | |
This is version 103 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |