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Protein

Tetraspanin-11

Gene

TSPAN11

Organism
Bos taurus (Bovine)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Biological processi

  • cell surface receptor signaling pathway Source: GO_Central

Names & Taxonomyi

Protein namesi
Recommended name:
Tetraspanin-11
Short name:
Tspan-11
Gene namesi
Name:TSPAN11
OrganismiBos taurus (Bovine)
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
Proteomesi
  • UP000009136 Componenti: Chromosome 5

Organism-specific databases

VGNCiVGNC:36426 TSPAN11

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei19 – 39HelicalSequence analysisAdd BLAST21
Transmembranei63 – 83HelicalSequence analysisAdd BLAST21
Transmembranei90 – 110HelicalSequence analysisAdd BLAST21
Transmembranei220 – 240HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003119041 – 253Tetraspanin-11Add BLAST253

Proteomic databases

PaxDbiQ0VC33
PRIDEiQ0VC33

Expressioni

Gene expression databases

BgeeiENSBTAG00000020699 Expressed in 9 organ(s), highest expression level in brain

Interactioni

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000040448

Family & Domainsi

Sequence similaritiesi

Belongs to the tetraspanin (TM4SF) family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG3882 Eukaryota
ENOG4111IRY LUCA
GeneTreeiENSGT00880000137851
HOGENOMiHOG000230651
HOVERGENiHBG107306
InParanoidiQ0VC33
KOiK17352
OMAiKQHLTRT
OrthoDBiEOG091G0CQO
TreeFamiTF352892

Family and domain databases

Gene3Di1.10.1450.10, 1 hit
InterProiView protein in InterPro
IPR000301 Tetraspanin
IPR018499 Tetraspanin/Peripherin
IPR008952 Tetraspanin_EC2_sf
PfamiView protein in Pfam
PF00335 Tetraspannin, 1 hit
PIRSFiPIRSF002419 Tetraspanin, 1 hit
PRINTSiPR00259 TMFOUR
SUPFAMiSSF48652 SSF48652, 1 hit

Sequencei

Sequence statusi: Complete.

Q0VC33-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAHYKVEQDD WLTVYLKYLL FIFNFFFWVG GAAVMAVGVW TLVEKSGYLG
60 70 80 90 100
VLASSTFAAS AYILIFAGAL VMVTGFLGFG AVIREDRGCL SAYFCLLLAI
110 120 130 140 150
FLVELVAGVL AHVYYQRLSD ELKQHLTRTL AENYRQPGAA EITASVDRLQ
160 170 180 190 200
QDFKCCGSNS SADWLQSSYI LSPEAEGRRV PDSCCKTVVA RCGQRAHPSN
210 220 230 240 250
IYKVEGGCIS KLEQFLADHL LLMGAVGIGV ACLQICGMIL TCGLHRRLQL

HFY
Length:253
Mass (Da):27,935
Last modified:September 5, 2006 - v1
Checksum:i1C348A1E1FEDF398
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC120376 mRNA Translation: AAI20377.1
RefSeqiNP_001073794.1, NM_001080325.1
XP_005207259.1, XM_005207202.3
UniGeneiBt.24648

Genome annotation databases

EnsembliENSBTAT00000042839; ENSBTAP00000040448; ENSBTAG00000020699
GeneIDi616660
KEGGibta:616660

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC120376 mRNA Translation: AAI20377.1
RefSeqiNP_001073794.1, NM_001080325.1
XP_005207259.1, XM_005207202.3
UniGeneiBt.24648

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000040448

Proteomic databases

PaxDbiQ0VC33
PRIDEiQ0VC33

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSBTAT00000042839; ENSBTAP00000040448; ENSBTAG00000020699
GeneIDi616660
KEGGibta:616660

Organism-specific databases

CTDi441631
VGNCiVGNC:36426 TSPAN11

Phylogenomic databases

eggNOGiKOG3882 Eukaryota
ENOG4111IRY LUCA
GeneTreeiENSGT00880000137851
HOGENOMiHOG000230651
HOVERGENiHBG107306
InParanoidiQ0VC33
KOiK17352
OMAiKQHLTRT
OrthoDBiEOG091G0CQO
TreeFamiTF352892

Gene expression databases

BgeeiENSBTAG00000020699 Expressed in 9 organ(s), highest expression level in brain

Family and domain databases

Gene3Di1.10.1450.10, 1 hit
InterProiView protein in InterPro
IPR000301 Tetraspanin
IPR018499 Tetraspanin/Peripherin
IPR008952 Tetraspanin_EC2_sf
PfamiView protein in Pfam
PF00335 Tetraspannin, 1 hit
PIRSFiPIRSF002419 Tetraspanin, 1 hit
PRINTSiPR00259 TMFOUR
SUPFAMiSSF48652 SSF48652, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiTSN11_BOVIN
AccessioniPrimary (citable) accession number: Q0VC33
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 4, 2007
Last sequence update: September 5, 2006
Last modified: November 7, 2018
This is version 70 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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