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Protein
Submitted name:

Colony stimulating factor 3 (Granulocyte)

Gene

Csf3

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Colony stimulating factor 3 (Granulocyte)Imported
Gene namesi
Name:Csf3Imported
ORF Names:mCG_21917Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:1339751 Csf3

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 30Sequence analysisAdd BLAST30
ChainiPRO_501430683131 – 208Sequence analysisAdd BLAST178

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi72 ↔ 78UniRule annotation
Disulfide bondi100 ↔ 110UniRule annotation

Keywords - PTMi

Disulfide bondUniRule annotation

Expressioni

Gene expression databases

BgeeiENSMUSG00000038067 Expressed in 32 organ(s), highest expression level in adult mammalian kidney

Interactioni

GO - Molecular functioni

Family & Domainsi

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiENOG410IIM2 Eukaryota
ENOG4111DA4 LUCA
HOVERGENiHBG005411
KOiK05423
OMAiHKLCHPE
OrthoDBiEOG091G0NDU

Family and domain databases

InterProiView protein in InterPro
IPR009079 4_helix_cytokine-like_core
IPR030474 IL-6/GCSF/MGF
IPR030473 IL6/GCSF/MGF_CS
PIRSFiPIRSF001935 IL6_MGF_GCSF, 1 hit
PRINTSiPR00433 IL6GCSFMGF
SMARTiView protein in SMART
SM00126 IL6, 1 hit
SUPFAMiSSF47266 SSF47266, 1 hit
PROSITEiView protein in PROSITE
PS00254 INTERLEUKIN_6, 1 hit

Sequencei

Sequence statusi: Complete.

Q0VB73-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAQLSAQRRM KLMALQLLLW QSALWSGREA VPLVTVSALP PSLPLPRSFL
60 70 80 90 100
LKSLEQVRKI QASGSVLLEQ LCATYKLCHP EELVLLGHSL GIPKASLSGC
110 120 130 140 150
SSQALQQTQC LSQLHSGLCL YQGLLQALSG ISPALAPTLD LLQLDVANFA
160 170 180 190 200
TTIWQQMENL GVAPTVQPTQ SAMPAFTSAF QRRAGGVLAI SYLQGFLETA

RLALHHLA
Length:208
Mass (Da):22,421
Last modified:September 5, 2006 - v1
Checksum:i0BF3622135C906DB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC120759 mRNA Translation: AAI20760.1
BC120761 mRNA Translation: AAI20762.1
CH466556 Genomic DNA Translation: EDL16160.1
RefSeqiNP_034101.1, NM_009971.1
UniGeneiMm.1238

Genome annotation databases

GeneIDi12985
KEGGimmu:12985

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC120759 mRNA Translation: AAI20760.1
BC120761 mRNA Translation: AAI20762.1
CH466556 Genomic DNA Translation: EDL16160.1
RefSeqiNP_034101.1, NM_009971.1
UniGeneiMm.1238

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi12985
KEGGimmu:12985

Organism-specific databases

CTDi1440
MGIiMGI:1339751 Csf3

Phylogenomic databases

eggNOGiENOG410IIM2 Eukaryota
ENOG4111DA4 LUCA
HOVERGENiHBG005411
KOiK05423
OMAiHKLCHPE
OrthoDBiEOG091G0NDU

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000038067 Expressed in 32 organ(s), highest expression level in adult mammalian kidney

Family and domain databases

InterProiView protein in InterPro
IPR009079 4_helix_cytokine-like_core
IPR030474 IL-6/GCSF/MGF
IPR030473 IL6/GCSF/MGF_CS
PIRSFiPIRSF001935 IL6_MGF_GCSF, 1 hit
PRINTSiPR00433 IL6GCSFMGF
SMARTiView protein in SMART
SM00126 IL6, 1 hit
SUPFAMiSSF47266 SSF47266, 1 hit
PROSITEiView protein in PROSITE
PS00254 INTERLEUKIN_6, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiQ0VB73_MOUSE
AccessioniPrimary (citable) accession number: Q0VB73
Entry historyiIntegrated into UniProtKB/TrEMBL: September 5, 2006
Last sequence update: September 5, 2006
Last modified: November 7, 2018
This is version 103 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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