UniProtKB - Q0UZM9 (Q0UZM9_PHANO)
Protein
Thioredoxin domain-containing protein
Gene
SNOG_02785
Organism
Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173) (Glume blotch fungus) (Parastagonospora nodorum)
Status
Functioni
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.UniRule annotation
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Active sitei | 89 | Cysteine sulfenic acid (-SOH) intermediateUniRule annotation | 1 |
GO - Molecular functioni
- peroxidase activity Source: GO_Central
- thioredoxin peroxidase activity Source: GO_Central
GO - Biological processi
- cell redox homeostasis Source: GO_Central
- cellular response to oxidative stress Source: GO_Central
Keywordsi
Molecular function | AntioxidantUniRule annotation, Oxidoreductase, PeroxidaseUniRule annotation |
Protein family/group databases
PeroxiBasei | 4978, Pno1CysPrx01 |
Names & Taxonomyi
Protein namesi | Recommended name: Thioredoxin domain-containing proteinInterPro annotation |
Gene namesi | ORF Names:SNOG_02785Imported |
Organismi | Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173) (Glume blotch fungus) (Parastagonospora nodorum)Imported |
Taxonomic identifieri | 321614 [NCBI] |
Taxonomic lineagei | Eukaryota › Fungi › Dikarya › Ascomycota › Pezizomycotina › Dothideomycetes › Pleosporomycetidae › Pleosporales › Pleosporineae › Phaeosphaeriaceae › Parastagonospora › |
Proteomesi |
|
Subcellular locationi
Cytosol
- cytosol Source: GO_Central
Mitochondrion
- mitochondrion Source: GO_Central
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 47 – 211 | ThioredoxinInterPro annotationAdd BLAST | 165 |
Sequence similaritiesi
Belongs to the peroxiredoxin family.UniRule annotation
Keywords - Domaini
Redox-active centerUniRule annotationPhylogenomic databases
eggNOGi | KOG0854, Eukaryota |
HOGENOMi | CLU_042529_4_2_1 |
InParanoidi | Q0UZM9 |
OrthoDBi | 1129256at2759 |
Family and domain databases
Gene3Di | 3.40.30.10, 1 hit |
InterProi | View protein in InterPro IPR000866, AhpC/TSA IPR024706, Peroxiredoxin_AhpC-typ IPR019479, Peroxiredoxin_C IPR036249, Thioredoxin-like_sf IPR013766, Thioredoxin_domain |
Pfami | View protein in Pfam PF10417, 1-cysPrx_C, 1 hit PF00578, AhpC-TSA, 1 hit |
PIRSFi | PIRSF000239, AHPC, 1 hit |
SUPFAMi | SSF52833, SSF52833, 1 hit |
PROSITEi | View protein in PROSITE PS51352, THIOREDOXIN_2, 1 hit |
i Sequence
Sequence statusi: Complete.
Q0UZM9-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSAFFPRAAS RALRCAARPT LSFQRPIAPL LRRGIKLPAE QPRLRLGSVG
60 70 80 90 100
LTAPNFQAKT THGDLDFHKF IDGKWVVLFS HPADFTPVCT TELGAFAKLK
110 120 130 140 150
PEFDARGVQM IGLSANDLTS HDEWVKDINE VGNTQVTFPI IADADRHVAF
160 170 180 190 200
LYDMISQDDL DNLAKNGGIA FTIRSVFIID PAKKIRLTMT YPASTGRNTS
210 220 230 240 250
EVLRVIDGLQ LADKKGIATP INWNAGEDVI VPPSVSTEDA RKKFGQDNVR
260
EVKKYLRYTN VGK
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CH445328 Genomic DNA Translation: EAT89516.2 |
RefSeqi | XP_001793381.1, XM_001793329.1 |
Genome annotation databases
EnsemblFungii | SNOT_02785; SNOT_02785; SNOG_02785 |
GeneIDi | 5970238 |
KEGGi | pno:SNOG_02785 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CH445328 Genomic DNA Translation: EAT89516.2 |
RefSeqi | XP_001793381.1, XM_001793329.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 13684.SNOT_02785 |
Protein family/group databases
PeroxiBasei | 4978, Pno1CysPrx01 |
Genome annotation databases
EnsemblFungii | SNOT_02785; SNOT_02785; SNOG_02785 |
GeneIDi | 5970238 |
KEGGi | pno:SNOG_02785 |
Phylogenomic databases
eggNOGi | KOG0854, Eukaryota |
HOGENOMi | CLU_042529_4_2_1 |
InParanoidi | Q0UZM9 |
OrthoDBi | 1129256at2759 |
Family and domain databases
Gene3Di | 3.40.30.10, 1 hit |
InterProi | View protein in InterPro IPR000866, AhpC/TSA IPR024706, Peroxiredoxin_AhpC-typ IPR019479, Peroxiredoxin_C IPR036249, Thioredoxin-like_sf IPR013766, Thioredoxin_domain |
Pfami | View protein in Pfam PF10417, 1-cysPrx_C, 1 hit PF00578, AhpC-TSA, 1 hit |
PIRSFi | PIRSF000239, AHPC, 1 hit |
SUPFAMi | SSF52833, SSF52833, 1 hit |
PROSITEi | View protein in PROSITE PS51352, THIOREDOXIN_2, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | Q0UZM9_PHANO | |
Accessioni | Q0UZM9Primary (citable) accession number: Q0UZM9 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | September 5, 2006 |
Last sequence update: | February 5, 2008 | |
Last modified: | December 2, 2020 | |
This is version 80 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |