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Entry version 65 (08 May 2019)
Sequence version 2 (05 Feb 2008)
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Protein

Clustered mitochondria protein homolog

Gene

CLU1

Organism
Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173) (Glume blotch fungus) (Parastagonospora nodorum)
Status
Reviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

mRNA-binding protein involved in proper cytoplasmic distribution of mitochondria.UniRule annotation

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • mRNA binding Source: GO_Central

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Clustered mitochondria protein homologUniRule annotation
Alternative name(s):
Protein TIF31 homologUniRule annotation
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:CLU1UniRule annotation
Synonyms:TIF31UniRule annotation
ORF Names:SNOG_14691
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiPhaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173) (Glume blotch fungus) (Parastagonospora nodorum)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri321614 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaDothideomycetesPleosporomycetidaePleosporalesPleosporineaePhaeosphaeriaceaeParastagonospora
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001055 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Cytoplasm

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003664111 – 1280Clustered mitochondria protein homologAdd BLAST1280

Proteomic databases

PRoteomics IDEntifications database

More...
PRIDEi
Q0U0H7

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

May associate with the eukaryotic translation initiation factor 3 (eIF-3) complex.

UniRule annotation

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
13684.SNOT_14691

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q0U0H7

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini338 – 582CluPROSITE-ProRule annotationAdd BLAST245

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the CLU family.UniRule annotation

Phylogenomic databases

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q0U0H7

KEGG Orthology (KO)

More...
KOi
K03255

Database of Orthologous Groups

More...
OrthoDBi
60958at2759

Family and domain databases

Conserved Domains Database

More...
CDDi
cd15466 CLU-central, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.25.40.10, 2 hits

HAMAP database of protein families

More...
HAMAPi
MF_03013 CLU, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR027523 CLU
IPR033646 CLU-central
IPR025697 CLU_dom
IPR028275 CLU_N
IPR011990 TPR-like_helical_dom_sf
IPR019734 TPR_repeat

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF13236 CLU, 1 hit
PF15044 CLU_N, 1 hit
PF12807 eIF3_p135, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00028 TPR, 3 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48452 SSF48452, 2 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51823 CLU, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q0U0H7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAASSNDASK SAMANSNVTT EVAQTPSKEQ DVNGEVEATE EDGANGQLPD
60 70 80 90 100
NIFQIKIKLP HEPFEIPMTI STAEQVQDLR QSIIEMPNTF QYSCFHLEHK
110 120 130 140 150
GQRINDFVDL SEVPELGPDS VLEVKEDPYN EKEARLHVIR VRELIGAAGD
160 170 180 190 200
RTDALHGIMA GLSLHDTVGL DQSGKPKEDG PEQSPLADYD FKSSGAIKNL
210 220 230 240 250
LPPPQEPAPK CIKSIALSAW NPPPYHLRTK GHLLYLVAMT NENEQHHITS
260 270 280 290 300
HVTGFYVNKS SNASFDPAPR QGPKALHAHS LLTLLEKLSP SFEASFQQLL
310 320 330 340 350
EHNAKKELLT IFQLSNAIPA NPWLVPPPTS SLTTHQPDLA RTQESYLISG
360 370 380 390 400
VENTDTLRDW NEEFQSTREM PKEAVHDRVF RERLTSKLFA DYNDAATRGA
410 420 430 440 450
MLVARGEIAP LNPTEAKDAQ IFVYNNIFYS FGADGVGTFG TEGGDEAARV
460 470 480 490 500
AVGKDVIGVR AVNNLDIPNL FTSGTVVVDF LGKRIVGQSI VPGIFKQRDP
510 520 530 540 550
GEHQIDYGAV EGKEIVADDK SFVPLFEQLS KALRVKKHPV WDKDNVRHEL
560 570 580 590 600
EGSVETKGLI GTDGRRYALD LYRLTPLDVA WIEAHWSEPS KDEDAKPSEK
610 620 630 640 650
NYPHRMATLR PELVESYGRL KLREYVKNEI DKKANKARGG RRRLPKAQKK
660 670 680 690 700
ADAGKEVDGE KKAEAEPEQD RVDISGFSFA LNPDVFSGQT PQSDEDKAEW
710 720 730 740 750
AKDEAEVRAA CDHLQTEVIP RMITELKDGE VGFPMDGQSL SSLLHKRGVN
760 770 780 790 800
IRYLGKIAEL SDKPDPRLQA LKRLIVQEMI ARGFKHFANS KLRNVSAPFS
810 820 830 840 850
AACVAHLLNC LLGADANAKP VAECDEEIKR MISTPEDDFS FEKLTPESLK
860 870 880 890 900
KEVIAQIALR YRYDLGESWV ESGKELQLLR EVSLKLGLQL QTRQYGFTKE
910 920 930 940 950
TLTNGAAVPT PAAPQTNGSS TSSKKKKNKT ITPPRADSPA VSLPSQTFHA
960 970 980 990 1000
DDILNIVPVI KEASPKSLLA EEALEAGRMS VAQDQKELGQ ELLLESLQLH
1010 1020 1030 1040 1050
EQIYGVLHPE VARAYHTLSN LLFNLDDKAS ALELAHKAVI VSERTLGVDH
1060 1070 1080 1090 1100
ADTVLAYLNL GLFEHASGNT KAALVYVRHA LELWKIIYGA DHPDSITTLN
1110 1120 1130 1140 1150
NAAVMLQAMK QYHESRIWFE ASLAICEDVS GKTSINTATL LFQTAQALAL
1160 1170 1180 1190 1200
DKDMRGAVNR MRESYNIFKD VLGAEDRNTK EAESWLEQLT QSAVSQAKQL
1210 1220 1230 1240 1250
NDLAKGRIRR IQLTGRNPLR PAAATPSVSD AAAAAGGQRT GTGRVDQRKI
1260 1270 1280
EDLLKYIEGE SSKTPTKKRT QNPRKRTQKP
Length:1,280
Mass (Da):141,616
Last modified:February 5, 2008 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iCBB48667DA16B14E
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
CH445357 Genomic DNA Translation: EAT77883.2

NCBI Reference Sequences

More...
RefSeqi
XP_001804874.1, XM_001804822.1

Genome annotation databases

Ensembl fungal genome annotation project

More...
EnsemblFungii
SNOT_14691; SNOT_14691; SNOG_14691

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
5981800

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
pno:SNOG_14691

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH445357 Genomic DNA Translation: EAT77883.2
RefSeqiXP_001804874.1, XM_001804822.1

3D structure databases

SMRiQ0U0H7
ModBaseiSearch...

Protein-protein interaction databases

STRINGi13684.SNOT_14691

Proteomic databases

PRIDEiQ0U0H7

Genome annotation databases

EnsemblFungiiSNOT_14691; SNOT_14691; SNOG_14691
GeneIDi5981800
KEGGipno:SNOG_14691

Phylogenomic databases

InParanoidiQ0U0H7
KOiK03255
OrthoDBi60958at2759

Family and domain databases

CDDicd15466 CLU-central, 1 hit
Gene3Di1.25.40.10, 2 hits
HAMAPiMF_03013 CLU, 1 hit
InterProiView protein in InterPro
IPR027523 CLU
IPR033646 CLU-central
IPR025697 CLU_dom
IPR028275 CLU_N
IPR011990 TPR-like_helical_dom_sf
IPR019734 TPR_repeat
PfamiView protein in Pfam
PF13236 CLU, 1 hit
PF15044 CLU_N, 1 hit
PF12807 eIF3_p135, 1 hit
SMARTiView protein in SMART
SM00028 TPR, 3 hits
SUPFAMiSSF48452 SSF48452, 2 hits
PROSITEiView protein in PROSITE
PS51823 CLU, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiCLU_PHANO
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q0U0H7
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: February 5, 2008
Last modified: May 8, 2019
This is version 65 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
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