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Protein

Methylglyoxal synthase

Gene

mgsA

Organism
Shigella flexneri serotype 5b (strain 8401)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.UniRule annotationSAAS annotation

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.UniRule annotation

Catalytic activityi

Glycerone phosphate = methylglyoxal + phosphate.UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei22SubstrateUniRule annotation1
Active sitei74UniRule annotation1
Active sitei74Proton donor/acceptorUniRule annotation1
Binding sitei101SubstrateUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLyaseUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Methylglyoxal synthaseUniRule annotationSAAS annotation (EC:4.2.3.3UniRule annotationSAAS annotation)
Short name:
MGSUniRule annotation
Gene namesi
Name:mgsAUniRule annotationImported
Ordered Locus Names:SFV_0973Imported
OrganismiShigella flexneri serotype 5b (strain 8401)Imported
Taxonomic identifieri373384 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeShigella
Proteomesi
  • UP000000659 Componenti: Chromosome

Structurei

3D structure databases

ProteinModelPortaliQ0T671
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini28 – 121MGSInterPro annotationAdd BLAST94

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni48 – 51Substrate bindingUniRule annotation4
Regioni68 – 69Substrate bindingUniRule annotation2

Sequence similaritiesi

Belongs to the methylglyoxal synthase family.UniRule annotationSAAS annotation

Phylogenomic databases

HOGENOMiHOG000283729
KOiK01734
OMAiRACDVHN

Family and domain databases

CDDicd01422 MGS, 1 hit
Gene3Di3.40.50.1380, 1 hit
HAMAPiMF_00549 Methylglyoxal_synth, 1 hit
InterProiView protein in InterPro
IPR004363 Methylgl_synth
IPR018148 Methylglyoxal_synth_AS
IPR011607 MGS-like_dom
IPR036914 MGS-like_dom_sf
PANTHERiPTHR30492 PTHR30492, 1 hit
PfamiView protein in Pfam
PF02142 MGS, 1 hit
PIRSFiPIRSF006614 Methylglyox_syn, 1 hit
SMARTiView protein in SMART
SM00851 MGS, 1 hit
SUPFAMiSSF52335 SSF52335, 1 hit
TIGRFAMsiTIGR00160 MGSA, 1 hit
PROSITEiView protein in PROSITE
PS01335 METHYLGLYOXAL_SYNTH, 1 hit

Sequencei

Sequence statusi: Complete.

Q0T671-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MYIMELTTRT LPARKHIALV AHDHCRQMLM SWVERHQPLL EQHVLYATGT
60 70 80 90 100
TGNLISRATG MNVNAMLSGP MGGDQQVGAL ISEGKIDVLI FFWDPLNAVP
110 120 130 140 150
HDPDVKALLR LATVWNIPVA TNVATADFII QSPHFNDAVD ILIPDYQRYL

ADRLK
Length:155
Mass (Da):17,354
Last modified:September 5, 2006 - v1
Checksum:i84FD8AC02CA137F2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000266 Genomic DNA Translation: ABF03194.1

Genome annotation databases

EnsemblBacteriaiABF03194; ABF03194; SFV_0973
KEGGisfv:SFV_0973

Similar proteinsi

Entry informationi

Entry nameiQ0T671_SHIF8
AccessioniPrimary (citable) accession number: Q0T671
Entry historyiIntegrated into UniProtKB/TrEMBL: September 5, 2006
Last sequence update: September 5, 2006
Last modified: April 25, 2018
This is version 78 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

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