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Protein
Submitted name:

N-acetylglucosamine-6-phosphate deacetylase

Gene

nagA

Organism
Clostridium perfringens (strain SM101 / Type A)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Cofactori

a divalent metal cationUniRule annotationNote: Binds 1 divalent metal cation per subunit.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi124Divalent metal cationUniRule annotation1
Binding sitei135Substrate; via amide nitrogenUniRule annotation1
Metal bindingi190Divalent metal cation; via tele nitrogenUniRule annotation1
Metal bindingi211Divalent metal cation; via tele nitrogenUniRule annotation1
Binding sitei222SubstrateUniRule annotation1
Binding sitei245Substrate; via tele nitrogenUniRule annotation1
Active sitei268Proton donor/acceptorUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolaseUniRule annotationImported
Biological processCarbohydrate metabolismUniRule annotation
LigandMetal-bindingUniRule annotation

Protein family/group databases

MEROPSiM38.983

Names & Taxonomyi

Protein namesi
Submitted name:
N-acetylglucosamine-6-phosphate deacetylaseImported (EC:3.5.1.25Imported)
Gene namesi
Name:nagAImported
Ordered Locus Names:CPR_2144Imported
OrganismiClostridium perfringens (strain SM101 / Type A)Imported
Taxonomic identifieri289380 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesClostridiaceaeClostridium
Proteomesi
  • UP000001824 Componenti: Chromosome

Structurei

3D structure databases

ProteinModelPortaliQ0SR06
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini45 – 374Amidohydro-relInterPro annotationAdd BLAST330

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni214 – 215Substrate bindingUniRule annotation2
Regioni301 – 303Substrate bindingUniRule annotation3

Sequence similaritiesi

Belongs to the metallo-dependent hydrolases superfamily. NagA family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000275009
KOiK01443
OMAiYMKNPRL

Family and domain databases

CDDicd00854 NagA, 1 hit
Gene3Di2.30.40.10, 2 hits
InterProiView protein in InterPro
IPR006680 Amidohydro-rel
IPR003764 GlcNAc_6-P_deAcase
IPR011059 Metal-dep_hydrolase_composite
IPR032466 Metal_Hydrolase
PANTHERiPTHR11113:SF1 PTHR11113:SF1, 1 hit
PfamiView protein in Pfam
PF01979 Amidohydro_1, 1 hit
PIRSFiPIRSF038994 NagA, 1 hit
SUPFAMiSSF51338 SSF51338, 2 hits
SSF51556 SSF51556, 1 hit
TIGRFAMsiTIGR00221 nagA, 1 hit

Sequencei

Sequence statusi: Complete.

Q0SR06-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MLIKDCNVVY LDKIEKGNIL IENGKIKAIN PKECNCEIID GEGLFLSPGF
60 70 80 90 100
IDVHIHGAGG HDTMDGTYEA INEISKVIVK HGTTSFLPTT MTVAAEDVCK
110 120 130 140 150
SMEAIHKAKT KGTDGANVLG AHLEGPFISP SAIGAQNPDF LIPPTKENFY
160 170 180 190 200
KLVGEHEDDV VSITLAPEVE GAKELTKFLS EKGIVVSMGH TKATYEEAME
210 220 230 240 250
GIKCGCSHAT HLFNAMTPFT HREPGVVGAV FDSEITTETI SDGIHIAYPS
260 270 280 290 300
LRVAYKQKGT DKVLLITDAM MACCMPDGMY SLGGQDVEVK NGAARLLSGS
310 320 330 340 350
LAGSILTLDV AVKNIFKNTN YSLNEVIKMA TYNGAKHCKV DDKKGLIKED
360 370
YDADLILFDD NIDIKYVIVN GKLVHKA
Length:377
Mass (Da):40,724
Last modified:September 5, 2006 - v1
Checksum:i7C3CA7D323B49EBB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000312 Genomic DNA Translation: ABG85412.1

Genome annotation databases

EnsemblBacteriaiABG85412; ABG85412; CPR_2144
KEGGicpr:CPR_2144

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000312 Genomic DNA Translation: ABG85412.1

3D structure databases

ProteinModelPortaliQ0SR06
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

MEROPSiM38.983

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABG85412; ABG85412; CPR_2144
KEGGicpr:CPR_2144

Phylogenomic databases

HOGENOMiHOG000275009
KOiK01443
OMAiYMKNPRL

Family and domain databases

CDDicd00854 NagA, 1 hit
Gene3Di2.30.40.10, 2 hits
InterProiView protein in InterPro
IPR006680 Amidohydro-rel
IPR003764 GlcNAc_6-P_deAcase
IPR011059 Metal-dep_hydrolase_composite
IPR032466 Metal_Hydrolase
PANTHERiPTHR11113:SF1 PTHR11113:SF1, 1 hit
PfamiView protein in Pfam
PF01979 Amidohydro_1, 1 hit
PIRSFiPIRSF038994 NagA, 1 hit
SUPFAMiSSF51338 SSF51338, 2 hits
SSF51556 SSF51556, 1 hit
TIGRFAMsiTIGR00221 nagA, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiQ0SR06_CLOPS
AccessioniPrimary (citable) accession number: Q0SR06
Entry historyiIntegrated into UniProtKB/TrEMBL: September 5, 2006
Last sequence update: September 5, 2006
Last modified: October 10, 2018
This is version 80 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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