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Protein

Elongation factor Tu

Gene

tuf

Organism
Borrelia afzelii (strain PKo)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.UniRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi19 – 26GTPUniRule annotation8
Nucleotide bindingi82 – 86GTPUniRule annotation5
Nucleotide bindingi137 – 140GTPUniRule annotation4

GO - Molecular functioni

Keywordsi

Molecular functionElongation factor
Biological processProtein biosynthesis
LigandGTP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Elongation factor TuUniRule annotation
Short name:
EF-TuUniRule annotation
Gene namesi
Name:tufUniRule annotation
Ordered Locus Names:BAPKO_0504, BafPKo_0493
OrganismiBorrelia afzelii (strain PKo)
Taxonomic identifieri390236 [NCBI]
Taxonomic lineageiBacteriaSpirochaetesSpirochaetalesBorreliaceaeBorreliella
Proteomesi
  • UP000005216 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000156191 – 394Elongation factor TuAdd BLAST394

Proteomic databases

PRIDEiQ0SN31

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi390236.BAPKO_0504

Structurei

3D structure databases

ProteinModelPortaliQ0SN31
SMRiQ0SN31
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini10 – 205tr-type GAdd BLAST196

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni19 – 26G1By similarity8
Regioni61 – 65G2By similarity5
Regioni82 – 85G3By similarity4
Regioni137 – 140G4By similarity4
Regioni173 – 175G5By similarity3

Sequence similaritiesi

Phylogenomic databases

eggNOGiENOG4105CGV Bacteria
COG0050 LUCA
HOGENOMiHOG000229290
KOiK02358
OMAiYGHIDCP
OrthoDBiPOG091H00LA

Family and domain databases

CDDicd03697 EFTU_II, 1 hit
HAMAPiMF_00118_B EF_Tu_B, 1 hit
InterProiView protein in InterPro
IPR004161 EFTu-like_2
IPR033720 EFTU_2
IPR031157 G_TR_CS
IPR027417 P-loop_NTPase
IPR005225 Small_GTP-bd_dom
IPR000795 TF_GTP-bd_dom
IPR009000 Transl_B-barrel_sf
IPR009001 Transl_elong_EF1A/Init_IF2_C
IPR004541 Transl_elong_EFTu/EF1A_bac/org
IPR004160 Transl_elong_EFTu/EF1A_C
PfamiView protein in Pfam
PF00009 GTP_EFTU, 1 hit
PF03144 GTP_EFTU_D2, 1 hit
PF03143 GTP_EFTU_D3, 1 hit
PRINTSiPR00315 ELONGATNFCT
SUPFAMiSSF50447 SSF50447, 1 hit
SSF50465 SSF50465, 1 hit
SSF52540 SSF52540, 1 hit
TIGRFAMsiTIGR00485 EF-Tu, 1 hit
TIGR00231 small_GTP, 1 hit
PROSITEiView protein in PROSITE
PS00301 G_TR_1, 1 hit
PS51722 G_TR_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q0SN31-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAKEVFQRTK PHMNVGTIGH VDHGKTTLTA AISIYCSKLN KDAKALKYED
60 70 80 90 100
IDNAPEEKAR GITINARHIE YETANRHYAH VDCPGHADYI KNMITGAAQM
110 120 130 140 150
DAAILLVAAD SGAEPQTKEH LLLAQRMGIK KIIVFLNKLD LADPELVELV
160 170 180 190 200
EVEVLELVEK YGFSANTPII KGSAFGAMSN PEDPEATKCV KELLESMDNY
210 220 230 240 250
FDLPERDIDK PFLLAVEDVF SISGRGTVAT GRIERGVIKV GQEVEIVGIK
260 270 280 290 300
ETRKTTVTGV EMFQKILEQG QAGDNVGLLL RGVDKKDIER GQVLSAPGTI
310 320 330 340 350
TPHKKFKASI YCLTKEEGGR HKPFFPGYRP QFFFRTTDVT GVVALEGKEM
360 370 380 390
VMPGDNVDIV VELISSIAMD KNVEFAVREG GRTVASGRIL EILE
Length:394
Mass (Da):43,354
Last modified:September 5, 2006 - v1
Checksum:i90CEEA2B0499A948
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000395 Genomic DNA Translation: ABH01747.1
CP002933 Genomic DNA Translation: AEL69701.1
RefSeqiWP_004789670.1, NC_017238.1

Genome annotation databases

EnsemblBacteriaiABH01747; ABH01747; BAPKO_0504
AEL69701; AEL69701; BafPKo_0493
KEGGibaf:BAPKO_0504
bafz:BafPKo_0493
PATRICifig|390236.22.peg.473

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000395 Genomic DNA Translation: ABH01747.1
CP002933 Genomic DNA Translation: AEL69701.1
RefSeqiWP_004789670.1, NC_017238.1

3D structure databases

ProteinModelPortaliQ0SN31
SMRiQ0SN31
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi390236.BAPKO_0504

Proteomic databases

PRIDEiQ0SN31

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABH01747; ABH01747; BAPKO_0504
AEL69701; AEL69701; BafPKo_0493
KEGGibaf:BAPKO_0504
bafz:BafPKo_0493
PATRICifig|390236.22.peg.473

Phylogenomic databases

eggNOGiENOG4105CGV Bacteria
COG0050 LUCA
HOGENOMiHOG000229290
KOiK02358
OMAiYGHIDCP
OrthoDBiPOG091H00LA

Family and domain databases

CDDicd03697 EFTU_II, 1 hit
HAMAPiMF_00118_B EF_Tu_B, 1 hit
InterProiView protein in InterPro
IPR004161 EFTu-like_2
IPR033720 EFTU_2
IPR031157 G_TR_CS
IPR027417 P-loop_NTPase
IPR005225 Small_GTP-bd_dom
IPR000795 TF_GTP-bd_dom
IPR009000 Transl_B-barrel_sf
IPR009001 Transl_elong_EF1A/Init_IF2_C
IPR004541 Transl_elong_EFTu/EF1A_bac/org
IPR004160 Transl_elong_EFTu/EF1A_C
PfamiView protein in Pfam
PF00009 GTP_EFTU, 1 hit
PF03144 GTP_EFTU_D2, 1 hit
PF03143 GTP_EFTU_D3, 1 hit
PRINTSiPR00315 ELONGATNFCT
SUPFAMiSSF50447 SSF50447, 1 hit
SSF50465 SSF50465, 1 hit
SSF52540 SSF52540, 1 hit
TIGRFAMsiTIGR00485 EF-Tu, 1 hit
TIGR00231 small_GTP, 1 hit
PROSITEiView protein in PROSITE
PS00301 G_TR_1, 1 hit
PS51722 G_TR_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiEFTU_BORAP
AccessioniPrimary (citable) accession number: Q0SN31
Secondary accession number(s): G0ISC0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: September 5, 2006
Last modified: October 10, 2018
This is version 82 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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