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Protein

Tail spike protein

Gene

21

Organism
Bacillus phage SPP1 (Bacteriophage SPP1)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Binds to the host entry receptor YueB and triggers viral DNA ejection. Binding to Yueb. This interaction initiates a cascade of conformational changes at the gp21 C-terminus causing disassembly of the tail spike organization and opening of the cap region formed by the N-terminus of gp21.1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionViral long flexible tail ejection system
Biological processHost-virus interaction, Viral attachment to host cell, Viral attachment to host entry receptor, Viral genome ejection through host cell envelope, Viral penetration into host cytoplasm, Virus entry into host cell

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Tail spike proteinCurated
Short name:
TSP
Alternative name(s):
Gene product 21
Short name:
Gp21
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:21
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiBacillus phage SPP1 (Bacteriophage SPP1)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10724 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiVirusesdsDNA viruses, no RNA stageCaudoviralesSiphoviridae
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section only exists in viral entries and indicates the host(s) either as a specific organism or taxonomic group of organisms that are susceptible to be infected by a virus.<p><a href='/help/virus_host' target='_top'>More...</a></p>Virus hostiBacillus subtilis [TaxID: 1423]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002559 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Genome

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Virion

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00004381421 – 1111Tail spike proteinAdd BLAST1111

Proteomic databases

PRoteomics IDEntifications database

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PRIDEi
Q0PDK6

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with host Yueb receptor; this interaction triggers viral DNA ejection.1 Publication

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

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SMRi
Q0PDK6

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides general information on the biological role of a domain. The term ‘domain’ is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

The N-terminus is part of the distal tail cap. The C-terminus is part of the spike structure and is probably involved in host receptor binding.1 Publication

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

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Gene3Di
2.60.120.260, 1 hit
2.60.40.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR008979 Galactose-bd-like_sf
IPR013783 Ig-like_fold
IPR007119 Phage_minor_struct_N
IPR010572 Prophage_Tail

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF06605 Prophage_tail, 1 hit

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR01665 put_anti_recept, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q0PDK6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MRSLSKNIWI MSNFEVLLTT LTGDRDAGGC RYWNGSFEEP LSPGETATYQ
60 70 80 90 100
FYADASHPNS KYVINDNKVI FKEPEQFGGD YRMFTIIDTE LGRSEQDGRY
110 120 130 140 150
IIATCEPAWY ELDDDFIENK RPTDKTPQEA LDLLLEGTRY EGEVDPDLQM
160 170 180 190 200
RASDSFYQVS VKEAVIQFFQ TWGGYFKDTI EFDGNEITRR VIKSLKRRGA
210 220 230 240 250
ANGVRFEHDK DITSIRRNIT GYPKTALYPY GASLEMTDED GNATGGYTRY
260 270 280 290 300
IDIKDVVWSK AAGDPVDKPA GQAWIGDPDL LKVFGRPMPD GSLRHRWTRW
310 320 330 340 350
QNEDITTPEE LIEAAYYDLI NNVSKAIVNY NVEVAPKNVK LGDTCIILDR
360 370 380 390 400
EFATPIELEA DVIKMTYFTD RPEEGATIEL GEYLNLDDIE RQIGAINDRF
410 420 430 440 450
KKNEGKWNTG GGITEVTDGA FPDKKPPKPS NITVKSMFQS IFLSWNYDPS
460 470 480 490 500
SYIAGYRVYA SKTPGFTPTD NDIIFEGKMS GYEHKVGNNE TWYYRLSTVN
510 520 530 540 550
YHKTESDMSD QYSAQSERIM NDDILFGAIT ADKLANLAVT ADKISRSFDE
560 570 580 590 600
GNIFPGSLLK PSQFYDYPNT KHSVTDKTFN ELTITQVIDD STRLRFGISG
610 620 630 640 650
QNKAPNNIQR MPLEQGQIYT LSFEVKRNNT TDLSYIHLKK PDNTFMLLSS
660 670 680 690 700
SLKDISAYPS DEFVRVDLQF TAPETSSKFT LGFGGYNRNG NVTPCSFVIR
710 720 730 740 750
KVQVRKGTEI KDYGYSPYDI MLVDGAIYSD YIQSAAINSA HIADAAIGSA
760 770 780 790 800
AIQNAAIKNA HLGTAIVDTA NIKDAAITSA KIKELSADLI TSGTINAINI
810 820 830 840 850
TGSLIRGGRF EPLNESSAYT SYIEGDKIYQ RVNTINYGGT PKKTYNDLTI
860 870 880 890 900
TSGGVTMVYG GRDTGTDEPL REMTLRDGSL YMSGNKNDTG YSEIQMYCND
910 920 930 940 950
DDVVNAPKSI FRQKLGGVNR MSLHSYYNSV PGSYNVQMDT RNTSIYSHFA
960 970 980 990 1000
NGWQLTADGK IMIMSKNGQG IYLDPSNDNV AGQVTMHVGN AGQAGGLIQP
1010 1020 1030 1040 1050
VIAGAPHYSI TDIHGALQTN MSVMLYQYNF VMPSKGDAYA SKYNDIPPPF
1060 1070 1080 1090 1100
ECENIFMVVP TVFGGYSDHV HATITSQSSS GFRCYVRGTG SSTGILGRTF
1110
QVRFLIFYEV N
Length:1,111
Mass (Da):123,953
Last modified:September 5, 2006 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i6743A97C141BE172
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

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DDBJi
Links Updated
X97918 Genomic DNA Translation: CAL18688.1

NCBI Reference Sequences

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RefSeqi
YP_009268706.1, NC_004166.2

Genome annotation databases

Database of genes from NCBI RefSeq genomes

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GeneIDi
955339

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
vg:955339

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X97918 Genomic DNA Translation: CAL18688.1
RefSeqiYP_009268706.1, NC_004166.2

3D structure databases

SMRiQ0PDK6
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiQ0PDK6

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi955339
KEGGivg:955339

Family and domain databases

Gene3Di2.60.120.260, 1 hit
2.60.40.10, 1 hit
InterProiView protein in InterPro
IPR008979 Galactose-bd-like_sf
IPR013783 Ig-like_fold
IPR007119 Phage_minor_struct_N
IPR010572 Prophage_Tail
PfamiView protein in Pfam
PF06605 Prophage_tail, 1 hit
TIGRFAMsiTIGR01665 put_anti_recept, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiFIBER_BPSPP
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q0PDK6
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 2, 2016
Last sequence update: September 5, 2006
Last modified: December 5, 2018
This is version 39 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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