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Protein

Potassium-transporting ATPase ATP-binding subunit

Gene

kdpB

Organism
Campylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system.UniRule annotation

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.UniRule annotation

Catalytic activityi

ATP + H2O + K+(Out) = ADP + phosphate + K+(In).UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei3054-aspartylphosphate intermediateUniRule annotation1
Binding sitei342ATPUniRule annotation1
Binding sitei346ATPUniRule annotation1
Binding sitei391ATPUniRule annotation1
Metal bindingi514MagnesiumUniRule annotation1
Metal bindingi518MagnesiumUniRule annotation1

GO - Molecular functioni

Keywordsi

Molecular functionHydrolaseUniRule annotationSAAS annotationImported
Biological processIon transport, Potassium transportUniRule annotationSAAS annotation, Transport
LigandATP-bindingUniRule annotationSAAS annotation, MagnesiumUniRule annotationSAAS annotation, Metal-bindingUniRule annotationSAAS annotation, Nucleotide-binding, Potassium

Enzyme and pathway databases

BioCyciCJEJ192222:G1G1F-651-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Potassium-transporting ATPase ATP-binding subunitUniRule annotation (EC:3.6.3.12UniRule annotation)
Alternative name(s):
ATP phosphohydrolase [potassium-transporting] B chainUniRule annotation
Potassium-binding and translocating subunit BUniRule annotation
Potassium-translocating ATPase B chainUniRule annotation
Gene namesi
Name:kdpBUniRule annotationImported
Ordered Locus Names:Cj0677Imported
OrganismiCampylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168)Imported
Taxonomic identifieri192222 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesCampylobacteraceaeCampylobacter
Proteomesi
  • UP000000799 Componenti: Chromosome

Subcellular locationi

  • Cell inner membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei34 – 52HelicalUniRule annotationAdd BLAST19
Transmembranei64 – 83HelicalUniRule annotationAdd BLAST20
Transmembranei217 – 238HelicalUniRule annotationAdd BLAST22
Transmembranei250 – 274HelicalUniRule annotationAdd BLAST25
Transmembranei580 – 600HelicalUniRule annotationAdd BLAST21
Transmembranei612 – 631HelicalUniRule annotationAdd BLAST20
Transmembranei652 – 676HelicalUniRule annotationAdd BLAST25

GO - Cellular componenti

Keywords - Cellular componenti

Cell inner membraneUniRule annotation, Cell membrane, Membrane

PTM / Processingi

Keywords - PTMi

PhosphoproteinUniRule annotation

Proteomic databases

PaxDbiQ0PAK1

Interactioni

Subunit structurei

The system is composed of three essential subunits: KdpA, KdpB and KdpC.UniRule annotationSAAS annotation

Protein-protein interaction databases

IntActiQ0PAK1, 1 interactor
STRINGi192222.Cj0677

Structurei

3D structure databases

ProteinModelPortaliQ0PAK1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily. [View classification]UniRule annotationSAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixUniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG4108F3I Bacteria
COG2216 LUCA
HOGENOMiHOG000244113
KOiK01547
OMAiILWLWFT

Family and domain databases

CDDicd02078 P-type_ATPase_K, 1 hit
Gene3Di3.40.1110.10, 1 hit
3.40.50.1000, 1 hit
HAMAPiMF_00285 KdpB, 1 hit
InterProiView protein in InterPro
IPR023299 ATPase_P-typ_cyto_dom_N
IPR018303 ATPase_P-typ_P_site
IPR023298 ATPase_P-typ_TM_dom_sf
IPR008250 ATPase_P-typ_transduc_dom_A_sf
IPR036412 HAD-like_sf
IPR023214 HAD_sf
IPR006391 P-type_ATPase_bsu_IA
IPR001757 P_typ_ATPase
PANTHERiPTHR43743 PTHR43743, 1 hit
SUPFAMiSSF56784 SSF56784, 3 hits
SSF81653 SSF81653, 1 hit
SSF81665 SSF81665, 3 hits
TIGRFAMsiTIGR01494 ATPase_P-type, 1 hit
TIGR01497 kdpB, 1 hit
PROSITEiView protein in PROSITE
PS00154 ATPASE_E1_E2, 1 hit

Sequencei

Sequence statusi: Complete.

Q0PAK1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSKKQNKLIT KEILNNAIKG AFLKFDPRFM VKNPVMFMVE VGSILTLILS
60 70 80 90 100
IFPTLFNGNS DERIYNILIT FILFIILFFA NFAESIAEGR GKAQAATLRQ
110 120 130 140 150
SKKDSKARHI KSDGSEEMLN SSELKIGDIV LVKAGELIPN DGEIIEGTAS
160 170 180 190 200
VDESAITGES APVMREAGGD FSSVTGGTTV LTDFLKIKIL VGAGESFLDK
210 220 230 240 250
MINLVEGAAR QKTPNEIALN TLLIVLSLSF LMVVVSLYPF MQFLGVSLPI
260 270 280 290 300
SWLVALLVCL IPTTIGGLLS AIGIAGMDRV TRFNVIALSG KAVESCGDVD
310 320 330 340 350
TMILDKTGTI TFGNRLANEF YEVQGISKEE MIKACVLSSL KDETPEGKSI
360 370 380 390 400
VALAQKMGYE LEGNDIKEFI EFSAQNRMSG VDLQDNTKIR KGAFDAIRAY
410 420 430 440 450
ISEMNGKIPS DLETKVMEIS NLGGTPLVVC KNEKILGVIY LKDTVKPGLK
460 470 480 490 500
ERFDELRKMG IKTLMCTGDN PLTAATITKE AGLDGFIAEC KPEDKIKAIK
510 520 530 540 550
KEQAQGKIVA MTGDGTNDAP VLTQADVGIA MNSGTQAAKE AANMIDLDSN
560 570 580 590 600
PTKILEVVEI GKGLLITRGS LTTFSMTNDI AKYFAILPAM FSVVLPQMQI
610 620 630 640 650
LNIMHLATPK SAILSALIFN AIIIPLLIPI AMRGVKFKPM KSEHLLLRNL
660 670 680
SIYGLGGMIA PFIGIKIIDI PTAWILRILG V
Length:681
Mass (Da):73,748
Last modified:September 19, 2006 - v1
Checksum:i611691C96F8C7DE3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL111168 Genomic DNA Translation: CAL34814.1
RefSeqiWP_002852255.1, NC_002163.1
YP_002344096.1, NC_002163.1

Genome annotation databases

EnsemblBacteriaiCAL34814; CAL34814; Cj0677
GeneIDi904995
KEGGicje:Cj0677
PATRICifig|192222.6.peg.669

Similar proteinsi

Entry informationi

Entry nameiQ0PAK1_CAMJE
AccessioniPrimary (citable) accession number: Q0PAK1
Entry historyiIntegrated into UniProtKB/TrEMBL: September 19, 2006
Last sequence update: September 19, 2006
Last modified: February 28, 2018
This is version 98 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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