UniProtKB - Q0P641 (CB080_HUMAN)
Protein
Uncharacterized protein C2orf80
Gene
C2orf80
Organism
Homo sapiens (Human)
Status
Names & Taxonomyi
Protein namesi | Recommended name: Uncharacterized protein C2orf80 |
Gene namesi | Name:C2orf80 |
Organismi | Homo sapiens (Human) |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:34352, C2orf80 |
MIMi | 615536, gene |
neXtProti | NX_Q0P641 |
VEuPathDBi | HostDB:ENSG00000188674.10 |
Pathology & Biotechi
Organism-specific databases
DisGeNETi | 389073 |
OpenTargetsi | ENSG00000188674 |
PharmGKBi | PA162379620 |
Miscellaneous databases
Pharosi | Q0P641, Tdark |
Genetic variation databases
BioMutai | C2orf80 |
DMDMi | 294862414 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000326123 | 1 – 193 | Uncharacterized protein C2orf80Add BLAST | 193 |
Proteomic databases
PaxDbi | Q0P641 |
PRIDEi | Q0P641 |
ProteomicsDBi | 58768 |
Expressioni
Gene expression databases
Bgeei | ENSG00000188674, Expressed in caudate nucleus and 106 other tissues |
ExpressionAtlasi | Q0P641, baseline and differential |
Genevisiblei | Q0P641, HS |
Organism-specific databases
HPAi | ENSG00000188674, Tissue enriched (brain) |
Interactioni
Protein-protein interaction databases
BioGRIDi | 132959, 1 interactor |
STRINGi | 9606.ENSP00000343171 |
Miscellaneous databases
RNActi | Q0P641, protein |
Family & Domainsi
Phylogenomic databases
eggNOGi | ENOG502S0E2, Eukaryota |
GeneTreei | ENSGT00390000004840 |
HOGENOMi | CLU_094619_0_0_1 |
InParanoidi | Q0P641 |
OMAi | RPIYPNH |
OrthoDBi | 1331662at2759 |
PhylomeDBi | Q0P641 |
TreeFami | TF338259 |
Family and domain databases
InterProi | View protein in InterPro IPR038776, C2orf80 |
PANTHERi | PTHR36296, PTHR36296, 1 hit |
Pfami | View protein in Pfam PF17718, DUF5563, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 6 potential isoforms that are computationally mapped.Show allAlign All
Q0P641-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MERRLIKKEM KKLLGDYIGI RLRENEFDPK GRRQLTFLDD MAHYDLAISV
60 70 80 90 100
ALQWLDPSED LTWLEWEELK IPLHGRPIYP NRREREAMIL SSYAGILMNS
110 120 130 140 150
IPIEEVFKIY GADSSADSGT IKVPRVSSLC LSLHPFAMLT APKAAAYARK
160 170 180 190
QSVKSRKVTT NKNATSISAK EANATEWKSS QRFSDTQPKH KVT
Computationally mapped potential isoform sequencesi
There are 6 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketC9J2L1 | C9J2L1_HUMAN | Uncharacterized protein C2orf80 | C2orf80 | 174 | Annotation score: | ||
H7BZF5 | H7BZF5_HUMAN | Uncharacterized protein C2orf80 | C2orf80 | 139 | Annotation score: | ||
C9J2S2 | C9J2S2_HUMAN | Uncharacterized protein C2orf80 | C2orf80 | 124 | Annotation score: | ||
C9JTX0 | C9JTX0_HUMAN | Uncharacterized protein C2orf80 | C2orf80 | 83 | Annotation score: | ||
C9JAS9 | C9JAS9_HUMAN | Uncharacterized protein C2orf80 | C2orf80 | 66 | Annotation score: | ||
H7C2Y3 | H7C2Y3_HUMAN | Uncharacterized protein C2orf80 | C2orf80 | 128 | Annotation score: |
Natural variant
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Natural variantiVAR_050717 | 82 | R → H. Corresponds to variant dbSNP:rs11898181Ensembl. | 1 | |
Natural variantiVAR_050718 | 130 | C → R1 PublicationCorresponds to variant dbSNP:rs6435421Ensembl. | 1 | |
Natural variantiVAR_050719 | 152 | S → G. Corresponds to variant dbSNP:rs10804166Ensembl. | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC016697 Genomic DNA No translation available. BC035737 mRNA Translation: AAH35737.1 |
CCDSi | CCDS42809.1 |
RefSeqi | NP_001092804.1, NM_001099334.2 XP_016859565.1, XM_017004076.1 |
Genome annotation databases
Ensembli | ENST00000341287; ENSP00000343171; ENSG00000188674 |
GeneIDi | 389073 |
KEGGi | hsa:389073 |
UCSCi | uc002vcr.4, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC016697 Genomic DNA No translation available. BC035737 mRNA Translation: AAH35737.1 |
CCDSi | CCDS42809.1 |
RefSeqi | NP_001092804.1, NM_001099334.2 XP_016859565.1, XM_017004076.1 |
3D structure databases
SMRi | Q0P641 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 132959, 1 interactor |
STRINGi | 9606.ENSP00000343171 |
Genetic variation databases
BioMutai | C2orf80 |
DMDMi | 294862414 |
Proteomic databases
PaxDbi | Q0P641 |
PRIDEi | Q0P641 |
ProteomicsDBi | 58768 |
Protocols and materials databases
Antibodypediai | 52192, 31 antibodies |
Genome annotation databases
Ensembli | ENST00000341287; ENSP00000343171; ENSG00000188674 |
GeneIDi | 389073 |
KEGGi | hsa:389073 |
UCSCi | uc002vcr.4, human |
Organism-specific databases
CTDi | 389073 |
DisGeNETi | 389073 |
GeneCardsi | C2orf80 |
HGNCi | HGNC:34352, C2orf80 |
HPAi | ENSG00000188674, Tissue enriched (brain) |
MIMi | 615536, gene |
neXtProti | NX_Q0P641 |
OpenTargetsi | ENSG00000188674 |
PharmGKBi | PA162379620 |
VEuPathDBi | HostDB:ENSG00000188674.10 |
GenAtlasi | Search... |
Phylogenomic databases
eggNOGi | ENOG502S0E2, Eukaryota |
GeneTreei | ENSGT00390000004840 |
HOGENOMi | CLU_094619_0_0_1 |
InParanoidi | Q0P641 |
OMAi | RPIYPNH |
OrthoDBi | 1331662at2759 |
PhylomeDBi | Q0P641 |
TreeFami | TF338259 |
Enzyme and pathway databases
PathwayCommonsi | Q0P641 |
Miscellaneous databases
BioGRID-ORCSi | 389073, 9 hits in 964 CRISPR screens |
GenomeRNAii | 389073 |
Pharosi | Q0P641, Tdark |
PROi | PR:Q0P641 |
RNActi | Q0P641, protein |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSG00000188674, Expressed in caudate nucleus and 106 other tissues |
ExpressionAtlasi | Q0P641, baseline and differential |
Genevisiblei | Q0P641, HS |
Family and domain databases
InterProi | View protein in InterPro IPR038776, C2orf80 |
PANTHERi | PTHR36296, PTHR36296, 1 hit |
Pfami | View protein in Pfam PF17718, DUF5563, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | CB080_HUMAN | |
Accessioni | Q0P641Primary (citable) accession number: Q0P641 Secondary accession number(s): A6NKZ3 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | March 18, 2008 |
Last sequence update: | April 20, 2010 | |
Last modified: | April 7, 2021 | |
This is version 88 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Human chromosome 2
Human chromosome 2: entries, gene names and cross-references to MIM - Human entries with genetic variants
List of human entries with genetic variants - Human variants curated from literature reports
Index of human variants curated from literature reports - MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot