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UniProtKB - Q0JPT5 (NIP12_ORYSJ)
Protein
Aquaporin NIP1-2
Gene
NIP1-2
Organism
Oryza sativa subsp. japonica (Rice)
Status
Functioni
Aquaporins facilitate the transport of water and small neutral solutes across cell membranes.
By similarityGO - Molecular functioni
- channel activity Source: InterPro
Keywordsi
Biological process | Transport |
Names & Taxonomyi
Protein namesi | Recommended name: Aquaporin NIP1-2Alternative name(s): NOD26-like intrinsic protein 1-2 OsNIP1;2 |
Gene namesi | Name:NIP1-2 Ordered Locus Names:Os01g0202800, Os01g0202900, LOC_Os01g10600 ORF Names:OsJ_000763, P0489A05.30 |
Organismi | Oryza sativa subsp. japonica (Rice) |
Taxonomic identifieri | 39947 [NCBI] |
Taxonomic lineagei | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliopsida › Liliopsida › Poales › Poaceae › BOP clade › Oryzoideae › Oryzeae › Oryzinae › Oryza › Oryza sativa |
Proteomesi |
|
Subcellular locationi
Other locations
- Membrane Curated; Multi-pass membrane protein Curated
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 66 – 86 | Helical; Name=1Sequence analysisAdd BLAST | 21 | |
Transmembranei | 91 – 111 | Helical; Name=2Sequence analysisAdd BLAST | 21 | |
Transmembranei | 145 – 165 | Helical; Name=3Sequence analysisAdd BLAST | 21 | |
Transmembranei | 188 – 208 | Helical; Name=4Sequence analysisAdd BLAST | 21 | |
Transmembranei | 212 – 232 | Helical; Name=5Sequence analysisAdd BLAST | 21 | |
Transmembranei | 255 – 275 | Helical; Name=6Sequence analysisAdd BLAST | 21 |
Keywords - Cellular componenti
MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000286027 | 1 – 303 | Aquaporin NIP1-2Add BLAST | 303 |
Proteomic databases
PaxDbi | Q0JPT5 |
Expressioni
Tissue specificityi
Expressed in roots and leaves, and at lower levels in anthers.1 Publication
Gene expression databases
Genevisiblei | Q0JPT5, OS |
Family & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 39 | DisorderedSequence analysisAdd BLAST | 39 |
Motif
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Motifi | 123 – 125 | NPA 1 | 3 | |
Motifi | 241 – 243 | NPA 2 | 3 |
Domaini
Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).
Sequence similaritiesi
Belongs to the MIP/aquaporin (TC 1.A.8) family. NIP (TC 1.A.8.12) subfamily. [View classification]Curated
Keywords - Domaini
Repeat, Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | KOG0223, Eukaryota |
HOGENOMi | CLU_020019_3_1_1 |
InParanoidi | Q0JPT5 |
Family and domain databases
CDDi | cd00333, MIP, 1 hit |
Gene3Di | 1.20.1080.10, 1 hit |
InterProi | View protein in InterPro IPR023271, Aquaporin-like IPR034294, Aquaporin_transptr IPR000425, MIP IPR022357, MIP_CS |
PANTHERi | PTHR45724, PTHR45724, 1 hit |
Pfami | View protein in Pfam PF00230, MIP, 1 hit |
PRINTSi | PR00783, MINTRINSICP |
SUPFAMi | SSF81338, SSF81338, 1 hit |
TIGRFAMsi | TIGR00861, MIP, 1 hit |
PROSITEi | View protein in PROSITE PS00221, MIP, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All
Q0JPT5-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MAGREDGAAA GAMEEGQDSK EVKCESSEDG SSSSSSSRCH GNDVISVQFM
60 70 80 90 100
QKVHPWCMCM NKNLLILAEI LGTYFMIFAG CGAVVVNQST GGAVTFPGIC
110 120 130 140 150
AVWGLVVMVL VYTVSHISGA HFNPAVTVAF ATCGRFRWKQ VPSYVVAQVL
160 170 180 190 200
GSTMASLTLR VVFGGGGGGA RGEHLFFGTT PAGSMAQAAA LEFVISFFLM
210 220 230 240 250
FVVSGVATDN RAIGELAGLA VGATVAVNVL FAGPVTGASM NPARSLGPAM
260 270 280 290 300
VAGRYGGVWV YVAAPVSGTV CGAWAYNLLR FTDKPLRDIA NTASFLRRSS
RRS
Computationally mapped potential isoform sequencesi
There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basketA0A0P0UZN2 | A0A0P0UZN2_ORYSJ | Os01g0202800 protein | Os01g0202800, OSNPB_010202800 | 267 | Annotation score: |
Sequence cautioni
The sequence BAF04242 differs from that shown. Reason: Erroneous gene model prediction. Was originally thought to correspond to two different genes Os01g0202800 and Os01g0202900.Curated
The sequence BAF04243 differs from that shown. Reason: Erroneous gene model prediction. Was originally thought to correspond to two different genes Os01g0202800 and Os01g0202900.Curated
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AP003105 Genomic DNA Translation: BAD73177.1 AP008207 Genomic DNA Translation: BAF04242.1 Sequence problems. AP008207 Genomic DNA Translation: BAF04243.2 Sequence problems. AP014957 Genomic DNA No translation available. CM000138 Genomic DNA Translation: EAZ10938.1 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AP003105 Genomic DNA Translation: BAD73177.1 AP008207 Genomic DNA Translation: BAF04242.1 Sequence problems. AP008207 Genomic DNA Translation: BAF04243.2 Sequence problems. AP014957 Genomic DNA No translation available. CM000138 Genomic DNA Translation: EAZ10938.1 |
3D structure databases
AlphaFoldDBi | Q0JPT5 |
SMRi | Q0JPT5 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 4530.OS01T0202800-00 |
Proteomic databases
PaxDbi | Q0JPT5 |
Phylogenomic databases
eggNOGi | KOG0223, Eukaryota |
HOGENOMi | CLU_020019_3_1_1 |
InParanoidi | Q0JPT5 |
Gene expression databases
Genevisiblei | Q0JPT5, OS |
Family and domain databases
CDDi | cd00333, MIP, 1 hit |
Gene3Di | 1.20.1080.10, 1 hit |
InterProi | View protein in InterPro IPR023271, Aquaporin-like IPR034294, Aquaporin_transptr IPR000425, MIP IPR022357, MIP_CS |
PANTHERi | PTHR45724, PTHR45724, 1 hit |
Pfami | View protein in Pfam PF00230, MIP, 1 hit |
PRINTSi | PR00783, MINTRINSICP |
SUPFAMi | SSF81338, SSF81338, 1 hit |
TIGRFAMsi | TIGR00861, MIP, 1 hit |
PROSITEi | View protein in PROSITE PS00221, MIP, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | NIP12_ORYSJ | |
Accessioni | Q0JPT5Primary (citable) accession number: Q0JPT5 Secondary accession number(s): Q0JPT6, Q5QN31 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | May 1, 2007 |
Last sequence update: | May 1, 2007 | |
Last modified: | May 25, 2022 | |
This is version 86 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Plant Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Oryza sativa (rice)
Index of Oryza sativa entries and their corresponding gene designations - SIMILARITY comments
Index of protein domains and families