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Entry version 83 (12 Aug 2020)
Sequence version 1 (03 Oct 2006)
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Protein

Protein argonaute 4B

Gene

AGO4B

Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Probably involved in the RNA silencing pathway. May bind to short RNAs such as microRNAs (miRNAs) or short interfering RNAs (siRNAs), and represses the translation of mRNAs which are complementary to them (By similarity).By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processRNA-mediated gene silencing

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Protein argonaute 4B
Short name:
OsAGO4b
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:AGO4B
Ordered Locus Names:Os04g0151800, LOC_Os04g06770
ORF Names:OsJ_13701
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiOryza sativa subsp. japonica (Rice)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri39947 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliopsidaLiliopsidaPoalesPoaceaeBOP cladeOryzoideaeOryzeaeOryzinaeOryzaOryza sativa
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000007752 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 4
  • UP000059680 Componenti: Chromosome 4
  • UP000000763 Componenti: Chromosome 4

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003784321 – 911Protein argonaute 4BAdd BLAST911

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q0JF58

PRoteomics IDEntifications database

More...
PRIDEi
Q0JF58

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q0JF58

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q0JF58, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q0JF58, OS

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
4530.OS04T0151800-02

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q0JF58

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini275 – 396PAZPROSITE-ProRule annotationAdd BLAST122
Domaini565 – 872PiwiPROSITE-ProRule annotationAdd BLAST308

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the argonaute family. Ago subfamily.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1041, Eukaryota

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_004544_2_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q0JF58

KEGG Orthology (KO)

More...
KOi
K11593

Identification of Orthologs from Complete Genome Data

More...
OMAi
FHYNVIL

Database of Orthologous Groups

More...
OrthoDBi
159407at2759

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.30.420.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR014811, ArgoL1
IPR032472, ArgoL2
IPR032473, Argonaute_Mid_dom
IPR032474, Argonaute_N
IPR003100, PAZ_dom
IPR036085, PAZ_dom_sf
IPR003165, Piwi
IPR012337, RNaseH-like_sf
IPR036397, RNaseH_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF08699, ArgoL1, 1 hit
PF16488, ArgoL2, 1 hit
PF16487, ArgoMid, 1 hit
PF16486, ArgoN, 1 hit
PF02170, PAZ, 1 hit
PF02171, Piwi, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM01163, DUF1785, 1 hit
SM00950, Piwi, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF101690, SSF101690, 1 hit
SSF53098, SSF53098, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50821, PAZ, 1 hit
PS50822, PIWI, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

Q0JF58-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDAHDGEADE LPPPPPVPAN VVPIKADDVE SEVPANKPAK PKRFPMARPG
60 70 80 90 100
LGRKGQPIQL LANHYKVSVK SSEEYFFHYN VILKYEDDRP VDGKGVGRKV
110 120 130 140 150
IDKLQQTYRS ELSSKDFAYD GEKSLFTIGA LPQVTNEFTV VLEDVSTGKT
160 170 180 190 200
AANGSPGGND SPGGSDRKRV RRPYQTKTFK VELCFAAKIP MNAIAQAIKG
210 220 230 240 250
QESENSQEAL RVLDIILRQH SAKQGCLLVR QSFFHNNPNN FVDLGGGVMG
260 270 280 290 300
CRGFHSSFRG TQSGLSLNID VSTTMIVKPG PVIDFLLANQ KVDHPDRIDW
310 320 330 340 350
QKAKRALKNL RIRTTPVNSE FKIIGLSDRN CNEQMFSLRQ RNGNNGDVDE
360 370 380 390 400
VEVTVYDYFV KNKGIELRYS GNLPCINVGK PKRPTYFPIE LCSLIPLQRY
410 420 430 440 450
TKALSTLQRS SLVEKSRQKP QERMSVLNDA LRHSNYDSDP MLRASGISIA
460 470 480 490 500
QNFTQVEGRV LQPPKLKAGN GEDIFPRNGR WNFNNKKLIQ TCSVDKWAVV
510 520 530 540 550
NFSARCDVRN LIRDLIRNAS AKGIQMAEPF DVFEESPSLR RAPVSRRVDD
560 570 580 590 600
MFEQIKSKLP GAPKFLLCLL PERKNCEVYG PWKRKCLAEF GIVTQCLAPQ
610 620 630 640 650
RVNDQYLLNL LLKINAKLGG INSLLQIEAS PSIPLVSKTP TIILGMDVSH
660 670 680 690 700
GQPGQSDRPS IAAVVSSRQW PLISKYRASV HTQSPKLEMM SSLFKPRGTE
710 720 730 740 750
DDGLIRESLI DFYTSSGKRK PDHVIVFRDG VSESQFTQVI NIELDQIIEA
760 770 780 790 800
CKFLDEKWSP KFTVIVAQKN HHTKFFQSGS PDNVPPGTVV DKQVCHPRNY
810 820 830 840 850
DFYMCAHAGM IGTTRPTHYH VLHDEIGFSP DDLQELVHSL SYVYQRSTTA
860 870 880 890 900
ISVVAPICYA HLAAAQVGTF LKFEDMSDAS SSQGGHTSVG SVPVPELPRL
910
HEKVRSSMFF C
Length:911
Mass (Da):101,740
Last modified:October 3, 2006 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i1502F495BC018520
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A0P0W6M1A0A0P0W6M1_ORYSJ
Os04g0151800 protein
Os04g0151800, OSNPB_040151800
294Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0P0W6U0A0A0P0W6U0_ORYSJ
Os04g0151800 protein
Os04g0151800, OSNPB_040151800
521Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti531D → V in AK122078 (PubMed:12869764).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AP008210 Genomic DNA Translation: BAF14029.1
AP014960 Genomic DNA Translation: BAS87801.1
CM000141 Genomic DNA Translation: EEE60454.1
AK122078 mRNA No translation available.

NCBI Reference Sequences

More...
RefSeqi
XP_015636673.1, XM_015781187.1

Genome annotation databases

Ensembl plant genome annotation project

More...
EnsemblPlantsi
Os04t0151800-01; Os04t0151800-01; Os04g0151800
Os04t0151800-02; Os04t0151800-02; Os04g0151800

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
4335025

Gramene; a comparative resource for plants

More...
Gramenei
Os04t0151800-01; Os04t0151800-01; Os04g0151800
Os04t0151800-02; Os04t0151800-02; Os04g0151800

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
osa:4335025

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP008210 Genomic DNA Translation: BAF14029.1
AP014960 Genomic DNA Translation: BAS87801.1
CM000141 Genomic DNA Translation: EEE60454.1
AK122078 mRNA No translation available.
RefSeqiXP_015636673.1, XM_015781187.1

3D structure databases

SMRiQ0JF58
ModBaseiSearch...

Protein-protein interaction databases

STRINGi4530.OS04T0151800-02

PTM databases

iPTMnetiQ0JF58

Proteomic databases

PaxDbiQ0JF58
PRIDEiQ0JF58

Genome annotation databases

EnsemblPlantsiOs04t0151800-01; Os04t0151800-01; Os04g0151800
Os04t0151800-02; Os04t0151800-02; Os04g0151800
GeneIDi4335025
GrameneiOs04t0151800-01; Os04t0151800-01; Os04g0151800
Os04t0151800-02; Os04t0151800-02; Os04g0151800
KEGGiosa:4335025

Phylogenomic databases

eggNOGiKOG1041, Eukaryota
HOGENOMiCLU_004544_2_0_1
InParanoidiQ0JF58
KOiK11593
OMAiFHYNVIL
OrthoDBi159407at2759

Gene expression databases

ExpressionAtlasiQ0JF58, baseline and differential
GenevisibleiQ0JF58, OS

Family and domain databases

Gene3Di3.30.420.10, 1 hit
InterProiView protein in InterPro
IPR014811, ArgoL1
IPR032472, ArgoL2
IPR032473, Argonaute_Mid_dom
IPR032474, Argonaute_N
IPR003100, PAZ_dom
IPR036085, PAZ_dom_sf
IPR003165, Piwi
IPR012337, RNaseH-like_sf
IPR036397, RNaseH_sf
PfamiView protein in Pfam
PF08699, ArgoL1, 1 hit
PF16488, ArgoL2, 1 hit
PF16487, ArgoMid, 1 hit
PF16486, ArgoN, 1 hit
PF02170, PAZ, 1 hit
PF02171, Piwi, 1 hit
SMARTiView protein in SMART
SM01163, DUF1785, 1 hit
SM00950, Piwi, 1 hit
SUPFAMiSSF101690, SSF101690, 1 hit
SSF53098, SSF53098, 1 hit
PROSITEiView protein in PROSITE
PS50821, PAZ, 1 hit
PS50822, PIWI, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiAGO4B_ORYSJ
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q0JF58
Secondary accession number(s): A0A0N7KIJ6
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 7, 2009
Last sequence update: October 3, 2006
Last modified: August 12, 2020
This is version 83 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Oryza sativa (rice)
    Index of Oryza sativa entries and their corresponding gene designations
  2. SIMILARITY comments
    Index of protein domains and families
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