UniProtKB - Q0IWL9 (GRS11_ORYSJ)
Protein
Monothiol glutaredoxin-S11
Gene
GRXS11
Organism
Oryza sativa subsp. japonica (Rice)
Status
Functioni
May only reduce GSH-thiol disulfides, but not protein disulfides.Curated
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Binding sitei | 411 | GlutathioneBy similarity | 1 | |
Metal bindingi | 419 | Iron-sulfur (2Fe-2S); shared with dimeric partnerBy similarity | 1 | |
Binding sitei | 448 | GlutathioneBy similarity | 1 | |
Binding sitei | 460 | Glutathione; via amide nitrogen and carbonyl oxygenBy similarity | 1 |
GO - Molecular functioni
- 2 iron, 2 sulfur cluster binding Source: UniProtKB-KW
- metal ion binding Source: UniProtKB-KW
- protein disulfide oxidoreductase activity Source: InterPro
GO - Biological processi
- cellular iron ion homeostasis Source: GO_Central
Keywordsi
Ligand | 2Fe-2S, Iron, Iron-sulfur, Metal-binding |
Names & Taxonomyi
Protein namesi | Recommended name: Monothiol glutaredoxin-S11 |
Gene namesi | Name:GRXS11 Ordered Locus Names:Os10g0500700, LOC_Os10g35720 ORF Names:OsJ_32056Imported, OSJNBa0078O01.9 |
Organismi | Oryza sativa subsp. japonica (Rice) |
Taxonomic identifieri | 39947 [NCBI] |
Taxonomic lineagei | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliopsida › Liliopsida › Poales › Poaceae › BOP clade › Oryzoideae › Oryzeae › Oryzinae › Oryza › Oryza sativa |
Proteomesi |
|
Subcellular locationi
Cytoplasm and Cytosol
- Cytoplasm By similarity
Keywords - Cellular componenti
CytoplasmPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000271280 | 1 – 491 | Monothiol glutaredoxin-S11Add BLAST | 491 |
Proteomic databases
PaxDbi | Q0IWL9 |
PRIDEi | Q0IWL9 |
Expressioni
Gene expression databases
ExpressionAtlasi | Q0IWL9, baseline and differential |
Genevisiblei | Q0IWL9, OS |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 151 – 253 | Glutaredoxin 1PROSITE-ProRule annotationAdd BLAST | 103 | |
Domaini | 287 – 389 | Glutaredoxin 2PROSITE-ProRule annotationAdd BLAST | 103 | |
Domaini | 394 – 491 | Glutaredoxin 3PROSITE-ProRule annotationAdd BLAST | 98 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 473 – 474 | Glutathione bindingBy similarity | 2 |
Sequence similaritiesi
Keywords - Domaini
Redox-active center, RepeatPhylogenomic databases
eggNOGi | KOG0911, Eukaryota |
HOGENOMi | CLU_026126_12_2_1 |
InParanoidi | Q0IWL9 |
OMAi | KPVMLFM |
Family and domain databases
CDDi | cd03028, GRX_PICOT_like, 3 hits |
Gene3Di | 3.40.30.10, 4 hits |
InterProi | View protein in InterPro IPR002109, Glutaredoxin IPR033658, GRX_PICOT-like IPR004480, Monothiol_GRX-rel IPR036249, Thioredoxin-like_sf IPR013766, Thioredoxin_domain |
PANTHERi | PTHR10293, PTHR10293, 4 hits |
Pfami | View protein in Pfam PF00462, Glutaredoxin, 3 hits PF00085, Thioredoxin, 1 hit |
SUPFAMi | SSF52833, SSF52833, 4 hits |
TIGRFAMsi | TIGR00365, TIGR00365, 2 hits |
PROSITEi | View protein in PROSITE PS51354, GLUTAREDOXIN_2, 3 hits PS51352, THIOREDOXIN_2, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All
Q0IWL9-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MAAVREVGSK AELEAAAGGA RAAAVHFWAA WCEASKQMDE VFAHLAVDFS
60 70 80 90 100
HAVFLRVEAE EQPEISEAYG VTAVPYFVFL KEGKTVDTLE GANPASLANK
110 120 130 140 150
VAKLAGPASV AESAVPASLG VAAGPAVLEK VQEMAQQNGA SATSSAEDAL
160 170 180 190 200
NKRLEQLVNS HPVFLFMKGT PEQPRCGFSR KVVDVLKQEG VEFGSFDILT
210 220 230 240 250
DNDVREGMKK FSNWPTFPQL YCKGELLGGC DIVIAMHESG ELKDVFKEHN
260 270 280 290 300
IPLQPQGSKN EEAVKAKPDT EKSGAVSEPA LLTAAQKERL ESLVNFSTVM
310 320 330 340 350
AFIKGTPEEP KCGFSGKLVH ILKQEKIPFS SFDILTDDEV RQGLKLLSNW
360 370 380 390 400
PSYPQLYING ELVGGSDIVM EMHKSGELKK VLSEKGIVAK ESLEDRLKAL
410 420 430 440 450
ISSAPVMLFM KGTPDAPRCG FSSKVVNALK QAGVSFGAFD ILSDEEVRQG
460 470 480 490
LKTYSNWPTF PQLYYKSELI GGCDIVLELE KSGELKSTLS E
Computationally mapped potential isoform sequencesi
There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basketA0A0P0XVV6 | A0A0P0XVV6_ORYSJ | Os10g0500700 protein | Os10g0500700, OSNPB_100500700 | 384 | Annotation score: |
Sequence cautioni
The sequence ABB47838 differs from that shown. Reason: Erroneous gene model prediction.Curated
The sequence BAF26896 differs from that shown. Reason: Erroneous gene model prediction.Curated
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC079888 Genomic DNA Translation: AAM93692.1 DP000086 Genomic DNA Translation: AAP54473.1 DP000086 Genomic DNA Translation: ABB47838.1 Sequence problems. AP008216 Genomic DNA Translation: BAF26896.1 Sequence problems. AP014966 Genomic DNA Translation: BAT11525.1 CM000147 Genomic DNA Translation: EAZ16584.1 AK059628 mRNA Translation: BAG87058.1 AK067982 mRNA Translation: BAG90695.1 |
Genome annotation databases
EnsemblPlantsi | Os10t0500700-01; Os10t0500700-01; Os10g0500700 |
Gramenei | Os10t0500700-01; Os10t0500700-01; Os10g0500700 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC079888 Genomic DNA Translation: AAM93692.1 DP000086 Genomic DNA Translation: AAP54473.1 DP000086 Genomic DNA Translation: ABB47838.1 Sequence problems. AP008216 Genomic DNA Translation: BAF26896.1 Sequence problems. AP014966 Genomic DNA Translation: BAT11525.1 CM000147 Genomic DNA Translation: EAZ16584.1 AK059628 mRNA Translation: BAG87058.1 AK067982 mRNA Translation: BAG90695.1 |
3D structure databases
SMRi | Q0IWL9 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 4530.OS10T0500700-01 |
Proteomic databases
PaxDbi | Q0IWL9 |
PRIDEi | Q0IWL9 |
Genome annotation databases
EnsemblPlantsi | Os10t0500700-01; Os10t0500700-01; Os10g0500700 |
Gramenei | Os10t0500700-01; Os10t0500700-01; Os10g0500700 |
Phylogenomic databases
eggNOGi | KOG0911, Eukaryota |
HOGENOMi | CLU_026126_12_2_1 |
InParanoidi | Q0IWL9 |
OMAi | KPVMLFM |
Gene expression databases
ExpressionAtlasi | Q0IWL9, baseline and differential |
Genevisiblei | Q0IWL9, OS |
Family and domain databases
CDDi | cd03028, GRX_PICOT_like, 3 hits |
Gene3Di | 3.40.30.10, 4 hits |
InterProi | View protein in InterPro IPR002109, Glutaredoxin IPR033658, GRX_PICOT-like IPR004480, Monothiol_GRX-rel IPR036249, Thioredoxin-like_sf IPR013766, Thioredoxin_domain |
PANTHERi | PTHR10293, PTHR10293, 4 hits |
Pfami | View protein in Pfam PF00462, Glutaredoxin, 3 hits PF00085, Thioredoxin, 1 hit |
SUPFAMi | SSF52833, SSF52833, 4 hits |
TIGRFAMsi | TIGR00365, TIGR00365, 2 hits |
PROSITEi | View protein in PROSITE PS51354, GLUTAREDOXIN_2, 3 hits PS51352, THIOREDOXIN_2, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | GRS11_ORYSJ | |
Accessioni | Q0IWL9Primary (citable) accession number: Q0IWL9 Secondary accession number(s): A3C671, Q337G2, Q8LNG2 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | January 9, 2007 |
Last sequence update: | January 9, 2007 | |
Last modified: | February 10, 2021 | |
This is version 95 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Plant Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Oryza sativa (rice)
Index of Oryza sativa entries and their corresponding gene designations - SIMILARITY comments
Index of protein domains and families