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Entry version 95 (10 Feb 2021)
Sequence version 2 (09 Jan 2007)
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Protein

Monothiol glutaredoxin-S11

Gene

GRXS11

Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May only reduce GSH-thiol disulfides, but not protein disulfides.Curated

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the interaction between a single amino acid and another chemical entity. Priority is given to the annotation of physiological ligands.<p><a href='/help/binding' target='_top'>More...</a></p>Binding sitei411GlutathioneBy similarity1
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section indicates at which position the protein binds a given metal ion. The nature of the metal is indicated in the 'Description' field.<p><a href='/help/metal' target='_top'>More...</a></p>Metal bindingi419Iron-sulfur (2Fe-2S); shared with dimeric partnerBy similarity1
Binding sitei448GlutathioneBy similarity1
Binding sitei460Glutathione; via amide nitrogen and carbonyl oxygenBy similarity1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Ligand2Fe-2S, Iron, Iron-sulfur, Metal-binding

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Monothiol glutaredoxin-S11
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:GRXS11
Ordered Locus Names:Os10g0500700, LOC_Os10g35720
ORF Names:OsJ_32056Imported, OSJNBa0078O01.9
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiOryza sativa subsp. japonica (Rice)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri39947 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliopsidaLiliopsidaPoalesPoaceaeBOP cladeOryzoideaeOryzeaeOryzinaeOryzaOryza sativa
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000007752 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 10
  • UP000059680 Componenti: Chromosome 10
  • UP000000763 Componenti: Chromosome 10

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Cytoplasm

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002712801 – 491Monothiol glutaredoxin-S11Add BLAST491

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q0IWL9

PRoteomics IDEntifications database

More...
PRIDEi
Q0IWL9

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q0IWL9, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q0IWL9, OS

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
4530.OS10T0500700-01

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q0IWL9

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini151 – 253Glutaredoxin 1PROSITE-ProRule annotationAdd BLAST103
Domaini287 – 389Glutaredoxin 2PROSITE-ProRule annotationAdd BLAST103
Domaini394 – 491Glutaredoxin 3PROSITE-ProRule annotationAdd BLAST98

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni473 – 474Glutathione bindingBy similarity2

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the glutaredoxin family. CGFS subfamily.Curated

Keywords - Domaini

Redox-active center, Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0911, Eukaryota

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_026126_12_2_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q0IWL9

Identification of Orthologs from Complete Genome Data

More...
OMAi
KPVMLFM

Family and domain databases

Conserved Domains Database

More...
CDDi
cd03028, GRX_PICOT_like, 3 hits

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.40.30.10, 4 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR002109, Glutaredoxin
IPR033658, GRX_PICOT-like
IPR004480, Monothiol_GRX-rel
IPR036249, Thioredoxin-like_sf
IPR013766, Thioredoxin_domain

The PANTHER Classification System

More...
PANTHERi
PTHR10293, PTHR10293, 4 hits

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00462, Glutaredoxin, 3 hits
PF00085, Thioredoxin, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF52833, SSF52833, 4 hits

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR00365, TIGR00365, 2 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51354, GLUTAREDOXIN_2, 3 hits
PS51352, THIOREDOXIN_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q0IWL9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAAVREVGSK AELEAAAGGA RAAAVHFWAA WCEASKQMDE VFAHLAVDFS
60 70 80 90 100
HAVFLRVEAE EQPEISEAYG VTAVPYFVFL KEGKTVDTLE GANPASLANK
110 120 130 140 150
VAKLAGPASV AESAVPASLG VAAGPAVLEK VQEMAQQNGA SATSSAEDAL
160 170 180 190 200
NKRLEQLVNS HPVFLFMKGT PEQPRCGFSR KVVDVLKQEG VEFGSFDILT
210 220 230 240 250
DNDVREGMKK FSNWPTFPQL YCKGELLGGC DIVIAMHESG ELKDVFKEHN
260 270 280 290 300
IPLQPQGSKN EEAVKAKPDT EKSGAVSEPA LLTAAQKERL ESLVNFSTVM
310 320 330 340 350
AFIKGTPEEP KCGFSGKLVH ILKQEKIPFS SFDILTDDEV RQGLKLLSNW
360 370 380 390 400
PSYPQLYING ELVGGSDIVM EMHKSGELKK VLSEKGIVAK ESLEDRLKAL
410 420 430 440 450
ISSAPVMLFM KGTPDAPRCG FSSKVVNALK QAGVSFGAFD ILSDEEVRQG
460 470 480 490
LKTYSNWPTF PQLYYKSELI GGCDIVLELE KSGELKSTLS E
Length:491
Mass (Da):53,155
Last modified:January 9, 2007 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i99387418D535BC00
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A0P0XVV6A0A0P0XVV6_ORYSJ
Os10g0500700 protein
Os10g0500700, OSNPB_100500700
384Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence ABB47838 differs from that shown. Reason: Erroneous gene model prediction.Curated
The sequence BAF26896 differs from that shown. Reason: Erroneous gene model prediction.Curated

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AC079888 Genomic DNA Translation: AAM93692.1
DP000086 Genomic DNA Translation: AAP54473.1
DP000086 Genomic DNA Translation: ABB47838.1 Sequence problems.
AP008216 Genomic DNA Translation: BAF26896.1 Sequence problems.
AP014966 Genomic DNA Translation: BAT11525.1
CM000147 Genomic DNA Translation: EAZ16584.1
AK059628 mRNA Translation: BAG87058.1
AK067982 mRNA Translation: BAG90695.1

Genome annotation databases

Ensembl plant genome annotation project

More...
EnsemblPlantsi
Os10t0500700-01; Os10t0500700-01; Os10g0500700

Gramene; a comparative resource for plants

More...
Gramenei
Os10t0500700-01; Os10t0500700-01; Os10g0500700

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC079888 Genomic DNA Translation: AAM93692.1
DP000086 Genomic DNA Translation: AAP54473.1
DP000086 Genomic DNA Translation: ABB47838.1 Sequence problems.
AP008216 Genomic DNA Translation: BAF26896.1 Sequence problems.
AP014966 Genomic DNA Translation: BAT11525.1
CM000147 Genomic DNA Translation: EAZ16584.1
AK059628 mRNA Translation: BAG87058.1
AK067982 mRNA Translation: BAG90695.1

3D structure databases

SMRiQ0IWL9
ModBaseiSearch...

Protein-protein interaction databases

STRINGi4530.OS10T0500700-01

Proteomic databases

PaxDbiQ0IWL9
PRIDEiQ0IWL9

Genome annotation databases

EnsemblPlantsiOs10t0500700-01; Os10t0500700-01; Os10g0500700
GrameneiOs10t0500700-01; Os10t0500700-01; Os10g0500700

Phylogenomic databases

eggNOGiKOG0911, Eukaryota
HOGENOMiCLU_026126_12_2_1
InParanoidiQ0IWL9
OMAiKPVMLFM

Gene expression databases

ExpressionAtlasiQ0IWL9, baseline and differential
GenevisibleiQ0IWL9, OS

Family and domain databases

CDDicd03028, GRX_PICOT_like, 3 hits
Gene3Di3.40.30.10, 4 hits
InterProiView protein in InterPro
IPR002109, Glutaredoxin
IPR033658, GRX_PICOT-like
IPR004480, Monothiol_GRX-rel
IPR036249, Thioredoxin-like_sf
IPR013766, Thioredoxin_domain
PANTHERiPTHR10293, PTHR10293, 4 hits
PfamiView protein in Pfam
PF00462, Glutaredoxin, 3 hits
PF00085, Thioredoxin, 1 hit
SUPFAMiSSF52833, SSF52833, 4 hits
TIGRFAMsiTIGR00365, TIGR00365, 2 hits
PROSITEiView protein in PROSITE
PS51354, GLUTAREDOXIN_2, 3 hits
PS51352, THIOREDOXIN_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiGRS11_ORYSJ
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q0IWL9
Secondary accession number(s): A3C671, Q337G2, Q8LNG2
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 9, 2007
Last sequence update: January 9, 2007
Last modified: February 10, 2021
This is version 95 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Oryza sativa (rice)
    Index of Oryza sativa entries and their corresponding gene designations
  2. SIMILARITY comments
    Index of protein domains and families
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