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UniProtKB - Q0IIM5 (Q0IIM5_BOVIN)
Protein
Solute carrier organic anion transporter family member
Gene
SLCO2B1
Organism
Bos taurus (Bovine)
Status
Functioni
Caution
Lacks conserved residue(s) required for the propagation of feature annotation.UniRule annotation
GO - Biological processi
- ion transport Source: UniProtKB-KW
- transmembrane transport Source: InterPro
Keywordsi
Biological process | Ion transportUniRule annotation, Transport |
Names & Taxonomyi
Protein namesi | Recommended name: Solute carrier organic anion transporter family memberUniRule annotation |
Gene namesi | Name:SLCO2B1Imported |
Organismi | Bos taurus (Bovine)Imported |
Taxonomic identifieri | 9913 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Laurasiatheria › Artiodactyla › Ruminantia › Pecora › Bovidae › Bovinae › Bos |
Subcellular locationi
Plasma membrane
- Cell membrane UniRule annotation; Multi-pass membrane protein UniRule annotation
Other locations
- Membrane ARBA annotation; Multi-pass membrane protein ARBA annotation
Plasma Membrane
- plasma membrane Source: UniProtKB-SubCell
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 89 – 110 | HelicalUniRule annotationAdd BLAST | 22 | |
Transmembranei | 117 – 138 | HelicalUniRule annotationAdd BLAST | 22 | |
Transmembranei | 184 – 203 | HelicalUniRule annotationAdd BLAST | 20 | |
Transmembranei | 224 – 252 | HelicalUniRule annotationAdd BLAST | 29 | |
Transmembranei | 272 – 296 | HelicalUniRule annotationAdd BLAST | 25 | |
Transmembranei | 371 – 393 | HelicalUniRule annotationAdd BLAST | 23 | |
Transmembranei | 405 – 431 | HelicalUniRule annotationAdd BLAST | 27 | |
Transmembranei | 443 – 463 | HelicalUniRule annotationAdd BLAST | 21 | |
Transmembranei | 559 – 586 | HelicalUniRule annotationAdd BLAST | 28 | |
Transmembranei | 607 – 630 | HelicalUniRule annotationAdd BLAST | 24 | |
Transmembranei | 650 – 672 | HelicalUniRule annotationAdd BLAST | 23 |
Keywords - Cellular componenti
MembraneExpressioni
Gene expression databases
Bgeei | ENSBTAG00000015596, Expressed in vertebral column and 95 other tissues |
Structurei
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 482 – 542 | Kazal-likeInterPro annotationAdd BLAST | 61 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 38 | DisorderedSequence analysisAdd BLAST | 38 | |
Regioni | 315 – 340 | DisorderedSequence analysisAdd BLAST | 26 | |
Regioni | 682 – 708 | DisorderedSequence analysisAdd BLAST | 27 |
Sequence similaritiesi
Belongs to the organo anion transporter (TC 2.A.60) family. [View classification]UniRule annotationARBA annotation
Keywords - Domaini
Transmembrane, Transmembrane helixUniRule annotationARBA annotationPhylogenomic databases
eggNOGi | KOG3626, Eukaryota |
HOGENOMi | CLU_008954_4_2_1 |
InParanoidi | Q0IIM5 |
OrthoDBi | 1029129at2759 |
TreeFami | TF317540 |
Family and domain databases
Gene3Di | 1.20.1250.20, 1 hit |
InterProi | View protein in InterPro IPR002350, Kazal_dom IPR036259, MFS_trans_sf IPR004156, OATP |
PANTHERi | PTHR11388, PTHR11388, 1 hit |
Pfami | View protein in Pfam PF03137, OATP, 1 hit |
SUPFAMi | SSF103473, SSF103473, 1 hit |
TIGRFAMsi | TIGR00805, oat, 1 hit |
PROSITEi | View protein in PROSITE PS51465, KAZAL_2, 1 hit |
i Sequence
Sequence statusi: Complete.
Q0IIM5-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MAPRIGPVGE ELQVPDKDAK AMVGTEDTPG SKASPNPQKL RPSVFHSIKF
60 70 80 90 100
FVLCHSLLQL AQLMISGYLK SSISTVEKRF GLSSQTSGLL AAFNEVGNTA
110 120 130 140 150
LIVFVSYFGS RVHRPRLIGC GAILVTLAGI LMTVPHFISE PYRYDRTSPD
160 170 180 190 200
MPQDFEASLC LPSTKALASA SSNSSCSSYT EARHLAVVGI MFTAQTLLGV
210 220 230 240 250
GGVPIQPFGI SYIDDFSHNS NSPLYLGILF AVTMMGPGMA YGLGSLMLRL
260 270 280 290 300
YVDIDRMPEG GINLTSKDPR WVGAWWLGFL ISAGAVALAA IPYFFFPKEM
310 320 330 340 350
PKEKQELRFR RKGLAVSDPP VSKGEDSSSE QSPADSPEKK DNLAQIAPDL
360 370 380 390 400
TVIQFIKVFP RVLLRTLRHP IFLLVVLSQV CMSSMAAGMA TFLPKFLERQ
410 420 430 440 450
FSVTASYANL LIGCLTIPLA IVGIVVGGIL VKRLRLGPVH CGTLCLLSAL
460 470 480 490 500
CCLVLSTPLF FMGCSSHQIA GISHQPGAQP GLELFPGCME SCSCPSDDFN
510 520 530 540 550
PVCDSSSRVE YITPCHAGCR SRVVQEAPDK SQVFYTNCSC VAGGGPVPAG
560 570 580 590 600
SCDSACGHLV LPFMILVSLG AALASVTHTP SFMLILRGVK KEDKTLAVGI
610 620 630 640 650
QFMLMRVLAW MPSPVIHGSA IDTTCVYWAH SCGRQAVCHY YDHDLLRNRF
660 670 680 690 700
IGLQFFFKTG SLACFALILA ILRQQDKEER TKATIPNPGL QQQLLASEAK
KEPEESRV
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BC122572 mRNA Translation: AAI22573.1 |
RefSeqi | NP_777268.2, NM_174843.2 |
Genome annotation databases
GeneIDi | 317704 |
KEGGi | bta:317704 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BC122572 mRNA Translation: AAI22573.1 |
RefSeqi | NP_777268.2, NM_174843.2 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
PaxDbi | Q0IIM5 |
Genome annotation databases
GeneIDi | 317704 |
KEGGi | bta:317704 |
Organism-specific databases
CTDi | 11309 |
Phylogenomic databases
eggNOGi | KOG3626, Eukaryota |
HOGENOMi | CLU_008954_4_2_1 |
InParanoidi | Q0IIM5 |
OrthoDBi | 1029129at2759 |
TreeFami | TF317540 |
Gene expression databases
Bgeei | ENSBTAG00000015596, Expressed in vertebral column and 95 other tissues |
Family and domain databases
Gene3Di | 1.20.1250.20, 1 hit |
InterProi | View protein in InterPro IPR002350, Kazal_dom IPR036259, MFS_trans_sf IPR004156, OATP |
PANTHERi | PTHR11388, PTHR11388, 1 hit |
Pfami | View protein in Pfam PF03137, OATP, 1 hit |
SUPFAMi | SSF103473, SSF103473, 1 hit |
TIGRFAMsi | TIGR00805, oat, 1 hit |
PROSITEi | View protein in PROSITE PS51465, KAZAL_2, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | Q0IIM5_BOVIN | |
Accessioni | Q0IIM5Primary (citable) accession number: Q0IIM5 Secondary accession number(s): F1MID2 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | October 3, 2006 |
Last sequence update: | October 3, 2006 | |
Last modified: | May 25, 2022 | |
This is version 108 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |