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Protein

Transaldolase

Gene

tal

Organism
Shewanella sp. (strain MR-4)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.UniRule annotation

Catalytic activityi

Sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = D-erythrose 4-phosphate + D-fructose 6-phosphate.UniRule annotation

Pathwayi: pentose phosphate pathway

This protein is involved in step 2 of the subpathway that synthesizes D-glyceraldehyde 3-phosphate and beta-D-fructose 6-phosphate from D-ribose 5-phosphate and D-xylulose 5-phosphate (non-oxidative stage).UniRule annotation
Proteins known to be involved in the 3 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. Transaldolase (tal)
  3. no protein annotated in this organism
This subpathway is part of the pathway pentose phosphate pathway, which is itself part of Carbohydrate degradation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes D-glyceraldehyde 3-phosphate and beta-D-fructose 6-phosphate from D-ribose 5-phosphate and D-xylulose 5-phosphate (non-oxidative stage), the pathway pentose phosphate pathway and in Carbohydrate degradation.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei132Schiff-base intermediate with substrateUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionTransferase
Biological processPentose shunt
LigandSchiff base

Enzyme and pathway databases

BioCyciSSP60480:G1G76-3120-MONOMER
UniPathwayiUPA00115; UER00414

Names & Taxonomyi

Protein namesi
Recommended name:
TransaldolaseUniRule annotation (EC:2.2.1.2UniRule annotation)
Gene namesi
Name:talUniRule annotation
Ordered Locus Names:Shewmr4_2967
OrganismiShewanella sp. (strain MR-4)
Taxonomic identifieri60480 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesShewanellaceaeShewanella

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000145281 – 318TransaldolaseAdd BLAST318

Interactioni

Subunit structurei

Homodimer.By similarity

Structurei

3D structure databases

ProteinModelPortaliQ0HFX9
SMRiQ0HFX9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the transaldolase family. Type 1 subfamily.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000281234
KOiK00616
OMAiMAFDKLH

Family and domain databases

CDDicd00957 Transaldolase_TalAB, 1 hit
Gene3Di3.20.20.70, 1 hit
HAMAPiMF_00492 Transaldolase_1, 1 hit
InterProiView protein in InterPro
IPR013785 Aldolase_TIM
IPR001585 TAL/FSA
IPR004730 Transaldolase_1
IPR018225 Transaldolase_AS
PANTHERiPTHR10683 PTHR10683, 1 hit
PTHR10683:SF20 PTHR10683:SF20, 1 hit
PfamiView protein in Pfam
PF00923 TAL_FSA, 1 hit
TIGRFAMsiTIGR00874 talAB, 1 hit
PROSITEiView protein in PROSITE
PS01054 TRANSALDOLASE_1, 1 hit
PS00958 TRANSALDOLASE_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q0HFX9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MANTLEQLKS YTTIVADTGD IEAIKRYQPE DATTNPSLIL KAAQIPEYSA
60 70 80 90 100
LIDNAIAWAK LQSADIEQQI DDASDKLAVN IGVEILKLVP GRISTEVDAR
110 120 130 140 150
LSFDKEKSIA KAHKLVRLYQ EAGVDKSRIL IKLASTWEGI CAAKELEQEG
160 170 180 190 200
INCNLTLLFS FAQARACAEA GVYLISPFVG RILDWYKKDT GKDYDAVNDP
210 220 230 240 250
GVVSVTEIYN YYKQHGYNTV VMGASFRNIG EIIELAGCDR LTIGPSLLEE
260 270 280 290 300
LANSQVTIQP KLIPASTTVA AGEPLTEAQF RWDFNQDPMA VDKLAEGIRN
310
FAIDQGKLEV MLKAKLAN
Length:318
Mass (Da):34,946
Last modified:October 3, 2006 - v1
Checksum:i3D152C6E81BD4D1C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000446 Genomic DNA Translation: ABI40038.1
RefSeqiWP_011623714.1, NC_008321.1

Genome annotation databases

EnsemblBacteriaiABI40038; ABI40038; Shewmr4_2967
KEGGishe:Shewmr4_2967

Similar proteinsi

Entry informationi

Entry nameiTAL_SHESM
AccessioniPrimary (citable) accession number: Q0HFX9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: October 3, 2006
Last modified: February 28, 2018
This is version 79 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

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