UniProtKB - Q0GKC8 (Q0GKC8_DANRE)
Protein
Submitted name:
Noxa
Gene
pmaip1
Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Functioni
GO - Molecular functioni
- protein heterodimerization activity Source: ZFIN
GO - Biological processi
- cellular response to DNA damage stimulus Source: InterPro
- positive regulation of apoptotic process Source: ZFIN
- positive regulation of mitotic nuclear division Source: ZFIN
- regulation of apoptotic process Source: ZFIN
- regulation of mitotic nuclear division Source: ZFIN
- release of cytochrome c from mitochondria Source: InterPro
Enzyme and pathway databases
Reactomei | R-DRE-111448, Activation of NOXA and translocation to mitochondria R-DRE-111453, BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members |
Names & Taxonomyi
Protein namesi | Submitted name: NoxaImportedSubmitted name: Phorbol-12-myristate-13-acetate-induced protein 1Imported |
Gene namesi | Name:pmaip1Imported |
Organismi | Danio rerio (Zebrafish) (Brachydanio rerio)Imported |
Taxonomic identifieri | 7955 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Actinopterygii › Neopterygii › Teleostei › Ostariophysi › Cypriniformes › Danionidae › Danioninae › Danio |
Proteomesi |
|
Organism-specific databases
ZFINi | ZDB-GENE-070119-3, pmaip1 |
Expressioni
Gene expression databases
Bgeei | ENSDARG00000089307, Expressed in female gonad and 34 other tissues |
Interactioni
GO - Molecular functioni
- protein heterodimerization activity Source: ZFIN
Protein-protein interaction databases
STRINGi | 7955.ENSDARP00000105705 |
Family & Domainsi
Phylogenomic databases
GeneTreei | ENSGT00980000199400 |
HOGENOMi | CLU_3207351_0_0_1 |
OrthoDBi | 1636703at2759 |
Family and domain databases
InterProi | View protein in InterPro IPR024140, Noxa |
Pfami | View protein in Pfam PF15150, PMAIP1, 1 hit |
i Sequence
Sequence statusi: Complete.
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CABZ01009277 Genomic DNA No translation available. BC134980 mRNA Translation: AAI34981.1 DQ860152 mRNA Translation: ABI18123.1 |
RefSeqi | NP_001038939.1, NM_001045474.3 |
Genome annotation databases
Ensembli | ENSDART00000123131; ENSDARP00000105705; ENSDARG00000089307 |
GeneIDi | 751765 |
KEGGi | dre:751765 |
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CABZ01009277 Genomic DNA No translation available. BC134980 mRNA Translation: AAI34981.1 DQ860152 mRNA Translation: ABI18123.1 |
RefSeqi | NP_001038939.1, NM_001045474.3 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 7955.ENSDARP00000105705 |
Genome annotation databases
Ensembli | ENSDART00000123131; ENSDARP00000105705; ENSDARG00000089307 |
GeneIDi | 751765 |
KEGGi | dre:751765 |
Organism-specific databases
CTDi | 5366 |
ZFINi | ZDB-GENE-070119-3, pmaip1 |
Phylogenomic databases
GeneTreei | ENSGT00980000199400 |
HOGENOMi | CLU_3207351_0_0_1 |
OrthoDBi | 1636703at2759 |
Enzyme and pathway databases
Reactomei | R-DRE-111448, Activation of NOXA and translocation to mitochondria R-DRE-111453, BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members |
Miscellaneous databases
PROi | PR:Q0GKC8 |
Gene expression databases
Bgeei | ENSDARG00000089307, Expressed in female gonad and 34 other tissues |
Family and domain databases
InterProi | View protein in InterPro IPR024140, Noxa |
Pfami | View protein in Pfam PF15150, PMAIP1, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | Q0GKC8_DANRE | |
Accessioni | Q0GKC8Primary (citable) accession number: Q0GKC8 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | October 3, 2006 |
Last sequence update: | October 3, 2006 | |
Last modified: | February 10, 2021 | |
This is version 77 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |