Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Chromosomal replication initiator protein DnaA

Gene

dnaA

Organism
Rhodobacterales bacterium HTCC2255
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.UniRule annotationSAAS annotation

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi151 – 158ATPUniRule annotation8

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingUniRule annotationSAAS annotation
Biological processDNA replicationUniRule annotationSAAS annotation
LigandATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciRBAC367336:G1GNW-1192-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Chromosomal replication initiator protein DnaAUniRule annotationSAAS annotation
Gene namesi
Name:dnaAUniRule annotationImported
ORF Names:OM2255_08756Imported
OrganismiRhodobacterales bacterium HTCC2255Imported
Taxonomic identifieri367336 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhodobacterales
Proteomesi
  • UP000009381 Componenti: Unassembled WGS sequence

Subcellular locationi

  • Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Interactioni

Protein-protein interaction databases

STRINGi367336.OM2255_08756

Structurei

3D structure databases

ProteinModelPortaliQ0FEB3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini143 – 271AAAInterPro annotationAdd BLAST129
Domaini359 – 428Bac_DnaA_CInterPro annotationAdd BLAST70

Sequence similaritiesi

Belongs to the DnaA family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG4105CI4 Bacteria
COG0593 LUCA
OrthoDBiPOG091H02FF

Family and domain databases

CDDicd06571 Bac_DnaA_C, 1 hit
Gene3Di1.10.1750.10, 1 hit
3.30.300.180, 1 hit
HAMAPiMF_00377 DnaA_bact, 1 hit
InterProiView protein in InterPro
IPR003593 AAA+_ATPase
IPR001957 Chromosome_initiator_DnaA
IPR020591 Chromosome_initiator_DnaA-like
IPR018312 Chromosome_initiator_DnaA_CS
IPR013317 DnaA
IPR013159 DnaA_C
IPR024633 DnaA_N_dom
IPR038454 DnaA_N_sf
IPR027417 P-loop_NTPase
IPR010921 Trp_repressor/repl_initiator
PANTHERiPTHR30050:SF2 PTHR30050:SF2, 1 hit
PfamiView protein in Pfam
PF00308 Bac_DnaA, 1 hit
PF08299 Bac_DnaA_C, 1 hit
PF11638 DnaA_N, 1 hit
PRINTSiPR00051 DNAA
SMARTiView protein in SMART
SM00382 AAA, 1 hit
SM00760 Bac_DnaA_C, 1 hit
SUPFAMiSSF48295 SSF48295, 1 hit
SSF52540 SSF52540, 1 hit
TIGRFAMsiTIGR00362 DnaA, 1 hit
PROSITEiView protein in PROSITE
PS01008 DNAA, 1 hit

Sequencei

Sequence statusi: Complete.

Q0FEB3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGIEIWPIIK LALRKTVGEA AFTNWINPLE LTSINASKAN FVTPTKFIGD
60 70 80 90 100
WVDRNYGDSI KFEFAKQGLD IERLVFSVNM EPKIAPTKKS SIKPESKNTK
110 120 130 140 150
TGSTDLPGAS LDPRYTFDNF VVGKPNELAH AAARRVSEGG DVSFNPLFLH
160 170 180 190 200
GGVGLGKTHL MHAIAWEIKK RDPNARVLYL SAEQFMYRFV QALRFKDTIS
210 220 230 240 250
FKEMFRSVDV LMVDDVQFIA GKSSTQEEFF HTFNALIDQN KQVIISGDRA
260 270 280 290 300
PVDMEQLEDR IKSRLQWGLV VDVHPTDYEL RLGILQSKQE SQARYNSTVE
310 320 330 340 350
VSPGVLEFMA QRISSNVRVL EGALTRLYAF GSLVGRPVTL EMAQESLSDI
360 370 380 390 400
LRATDRKVTI DEIIRKVTDH YGVNLTDMLS ARRTRSIARP RQVAMYLSKK
410 420 430 440 450
LTSKSLPEIG RRFGKRDHTT VIHAVKKIEE LQSIDNQIAK DIEVLRRMLE

G
Length:451
Mass (Da):51,019
Last modified:October 17, 2006 - v1
Checksum:i109570BB1E04716F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AATR01000002 Genomic DNA Translation: EAU52231.1
RefSeqiWP_008035325.1, NZ_DS022282.1

Genome annotation databases

EnsemblBacteriaiEAU52231; EAU52231; OM2255_08756

Similar proteinsi

Entry informationi

Entry nameiQ0FEB3_9RHOB
AccessioniPrimary (citable) accession number: Q0FEB3
Entry historyiIntegrated into UniProtKB/TrEMBL: October 17, 2006
Last sequence update: October 17, 2006
Last modified: July 18, 2018
This is version 73 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health