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Entry version 115 (31 Jul 2019)
Sequence version 1 (17 Oct 2006)
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Protein
Submitted name:

Down syndrome cell adhesion molecule 1, isoform AU

Gene

Dscam1

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section indicates at which position the protein binds a given metal ion. The nature of the metal is indicated in the ‘Description’ field.<p><a href='/help/metal' target='_top'>More...</a></p>Metal bindingi44Zinc 1Combined sources1
Metal bindingi130Zinc 2Combined sources1
Metal bindingi132Zinc 2; via tele nitrogenCombined sources1
Metal bindingi144Zinc 3Combined sources1
Metal bindingi161Zinc 3Combined sources1
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the interaction between a single amino acid and another chemical entity. Priority is given to the annotation of physiological ligands.<p><a href='/help/binding' target='_top'>More...</a></p>Binding sitei185MannoseCombined sources1
Binding sitei356MannoseCombined sources1
Metal bindingi418Zinc 1Combined sources1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

LigandMetal-bindingCombined sources, ZincCombined sources

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Down syndrome cell adhesion molecule 1, isoform AUImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Dscam1Imported
Synonyms:43BcImported, CT39257Imported, Dm_2R:13579Imported, Dm_2R:13612Imported, DmDscamImported, Dmel\CG17800Imported, DSCAMImported, DScamImported, DsCamImported, DscamImported, dScamImported, dscamImported, Dscam-hvImported, dscam1Imported, DsmImported, l(2)05518Imported, l(2)43BcImported, Neu1Imported, p270Imported
ORF Names:CG17800Imported, Dmel_CG17800Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDrosophila melanogaster (Fruit fly)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7227 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000803 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 2R

Organism-specific databases

Drosophila genome database

More...
FlyBasei
FBgn0033159 Dscam1

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei1621 – 1642HelicalSequence analysisAdd BLAST22

Keywords - Cellular componenti

Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 28Sequence analysisAdd BLAST28
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_500417129229 – 2018Sequence analysisAdd BLAST1990

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi53N-linked (GlcNAc...) asparagineCombined sources1
<p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi61 ↔ 117Combined sources
Disulfide bondi160 ↔ 219Combined sources
Disulfide bondi272 ↔ 325Combined sources
Glycosylationi328N-linked (GlcNAc...) asparagineCombined sources1
Disulfide bondi367 ↔ 408Combined sources

Proteomic databases

PRoteomics IDEntifications database

More...
PRIDEi
Q0E9L5

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
FBgn0033159 Expressed in 25 organ(s), highest expression level in embryo

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q0E9L5 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q0E9L5 DM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q0E9L5

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini39 – 134Ig-likeInterPro annotationAdd BLAST96
Domaini249 – 341Ig-likeInterPro annotationAdd BLAST93
Domaini345 – 424Ig-likeInterPro annotationAdd BLAST80
Domaini431 – 525Ig-likeInterPro annotationAdd BLAST95
Domaini530 – 616Ig-likeInterPro annotationAdd BLAST87
Domaini621 – 712Ig-likeInterPro annotationAdd BLAST92
Domaini717 – 809Ig-likeInterPro annotationAdd BLAST93
Domaini814 – 906Ig-likeInterPro annotationAdd BLAST93
Domaini915 – 1009Fibronectin type-IIIInterPro annotationAdd BLAST95
Domaini1014 – 1118Fibronectin type-IIIInterPro annotationAdd BLAST105
Domaini1119 – 1215Fibronectin type-IIIInterPro annotationAdd BLAST97
Domaini1219 – 1312Fibronectin type-IIIInterPro annotationAdd BLAST94
Domaini1314 – 1396Ig-likeInterPro annotationAdd BLAST83
Domaini1404 – 1497Fibronectin type-IIIInterPro annotationAdd BLAST94
Domaini1501 – 1596Fibronectin type-IIIInterPro annotationAdd BLAST96

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1690 – 1721DisorderedSequence analysisAdd BLAST32
Regioni1789 – 1848DisorderedSequence analysisAdd BLAST60
Regioni1864 – 2018DisorderedSequence analysisAdd BLAST155

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi1811 – 1838PolarSequence analysisAdd BLAST28
Compositional biasi1950 – 1967PolyampholyteSequence analysisAdd BLAST18
Compositional biasi1977 – 1994PolyampholyteSequence analysisAdd BLAST18
Compositional biasi1996 – 2010PolarSequence analysisAdd BLAST15

Keywords - Domaini

RepeatSAAS annotation, SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00063 FN3, 6 hits

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.60.40.10, 16 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR021012 Dscam_C
IPR003961 FN3_dom
IPR036116 FN3_sf
IPR007110 Ig-like_dom
IPR036179 Ig-like_dom_sf
IPR013783 Ig-like_fold
IPR013098 Ig_I-set
IPR003599 Ig_sub
IPR003598 Ig_sub2

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF12355 Dscam_C, 1 hit
PF00041 fn3, 6 hits
PF07679 I-set, 5 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00060 FN3, 6 hits
SM00409 IG, 10 hits
SM00408 IGc2, 10 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48726 SSF48726, 9 hits
SSF49265 SSF49265, 3 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50853 FN3, 6 hits
PS50835 IG_LIKE, 9 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 74 potential isoforms that are computationally mapped.Show allAlign All

Q0E9L5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MNMPNERLKW LMLFAAVALI ACGSQTLAAN PPDADQKGPV FLKEPTNRID
60 70 80 90 100
FSNSTGAEIE CKASGNPMPE IIWIRSDGTA VGDVPGLRQI SSDGKLVFPP
110 120 130 140 150
FRAEDYRQEV HAQVYACLAR NQFGSIISRD VHVRAVVIQS YESEADNEYV
160 170 180 190 200
IRGNSVVMKC EIPSYVADFV FVDLWLDSEG RNYYPNNAAE TDGKYLVLPS
210 220 230 240 250
GELHIREVGP EDGYKSYQCR TKHRLTGETR LSATKGRLVI TEPISAKAPV
260 270 280 290 300
LAVDTKWSGI ERHRDMDIVL LCPAQAYPVP ISRWYKFIEG TTRKQAVVLN
310 320 330 340 350
DRVKQVSGTL IIKDAVVEDS GKYLCVVNNS VGGESVETVL TVTAPLSAKI
360 370 380 390 400
DPPTQTVDFG RPAVFTCQYT GNPIKTVSWM KDGKAIGHSE PVLRIESVKK
410 420 430 440 450
EDKGMYQCFV RNDQESAEAS AELKLGGRFD PPVIRQAFQE ETMEPGPSVF
460 470 480 490 500
LKCVAGGNPT PEISWELDGK KIANNDRYQV GQYVTVNGDV VSYLNITSVH
510 520 530 540 550
ANDGGLYKCI AKSKVGVAEH SAKLNVYGLP YIRQMEKKAI VAGETLIVTC
560 570 580 590 600
PVAGYPIDSI VWERDNRALP INRKQKVFPN GTLIIENVER NSDQATYTCV
610 620 630 640 650
AKNQEGYSAR GSLEVQVMVL PQVVPFDFGE ESINELDMVS ASCTVNKGDL
660 670 680 690 700
PVDIYWTKNG GRVYTNDGLI VTRNSQRLSV LSIESVRARH AGNYSCVATN
710 720 730 740 750
NAGAITQSAM LAVNVPPRWI LEPTDKAFAQ GSDAKVECKA DGFPKPQVTW
760 770 780 790 800
KKAVGDTPGE YKDLKKSDNI RVEEGTLHVD NIQKTNEGYY LCEAINGIGS
810 820 830 840 850
GLSAVIMISV QAPPEFTEKL RNQTARRGEP AVLQCEAKGE KPIGILWNMN
860 870 880 890 900
NMRLDPKNDN RYTIREEILS TGVMSSLSIK RTERSDSALF TCVATNAFGS
910 920 930 940 950
DDASINMIVQ EVPEMPYALK VLDKSGRSVQ LSWAQPYDGN SPLDRYIIEF
960 970 980 990 1000
KRSRASWSEI DRVIVPGHTT EAQVQKLSPA TTYNIRIVAE NAIGTSQSSE
1010 1020 1030 1040 1050
AVTIITAEEA PSGKPQNIKV EPVNQTTMRV TWKPPPRTEW NGEILGYYVG
1060 1070 1080 1090 1100
YKLSNTNSSY VFETINFITE EGKEHNLELQ NLRVYTQYSV VIQAFNKIGA
1110 1120 1130 1140 1150
GPLSEEEKQF TAEGTPSQPP SDTACTTLTS QTIRVGWVSP PLESANGVIK
1160 1170 1180 1190 1200
TYKVVYAPSD EWYDETKRHY KKTASSDTVL HGLKKYTNYT MQVLATTAGG
1210 1220 1230 1240 1250
DGVRSVPIHC QTEPDVPEAP TDVKALVMGN AAILVSWRPP AQPNGIITQY
1260 1270 1280 1290 1300
TVYSKAEGAE TETKTQKVPH YQMSFEATEL EKNKPYEFWV TASTTIGEGQ
1310 1320 1330 1340 1350
QSKSIVAMPS DQVPAKIASF DDTFTATFKE DAKMPCLAVG APQPEITWKI
1360 1370 1380 1390 1400
KGVEFSANDR MRVLPDGSLL IKSVNRQDAG DYSCHAENSI AKDSITHKLI
1410 1420 1430 1440 1450
VLAPPQSPHV TLSATTTDAL TVKLKPHEGD TAPLHGYTLH YKPEFGEWET
1460 1470 1480 1490 1500
SEVSVDSQKH NIEGLLCGSR YQVYATGFNN IGAGEASDIL NTRTKGQKPK
1510 1520 1530 1540 1550
LPEKPRFIEV SSNSVSLHFK AWKDGGCPMS HFVVESKKRD QIEWNQISNN
1560 1570 1580 1590 1600
VKPDNNYVVL DLEPATWYNL RITAHNSAGF TVAEYDFATL TVTGGTIAPS
1610 1620 1630 1640 1650
RDLPELSAED TIRIILSNLN LVVPVVAALL VIIIAIIVIC ILRSKGNHHK
1660 1670 1680 1690 1700
DDVVYNQTMG PGATLDKRRP DLRDELGYIA PPNRKLPPVP GSNYNTCDRI
1710 1720 1730 1740 1750
KRGRGGLRSN HSTWDPRRNP NLYEELKAPP VPMHGNHYGH AHGNAECHYR
1760 1770 1780 1790 1800
HPGMEDEICP YATFHLLGFR EEMDPTKAMN FQTFPHQNGH AGPVPGHAGT
1810 1820 1830 1840 1850
MLPPGHPGHV HSRSGSQSMP RANRYQRKNS QGGQSSIYTP APEYDDPANC
1860 1870 1880 1890 1900
AEEDQYRRYT RVNSQGGSLY SGPGPEYDDP ANCAPEEDQY GSQYGGPYGQ
1910 1920 1930 1940 1950
PYDHYGSRGS MGRRSIGSAR NPGNGSPEPP PPPPRNHDMS NSSFNDSKES
1960 1970 1980 1990 2000
NEISEAECDR DHGPRGNYGA VKRSPQPKDQ RTTEEMRKLI ERNETGPKQL
2010
QLQQANGAGF TAYDTMAV
Length:2,018
Mass (Da):222,606
Last modified:October 17, 2006 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i894B25E27758A5C9
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 74 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A0B4K823A0A0B4K823_DROME
Down syndrome cell adhesion molecul...
Dscam1 43Bc, CT39257, Dm_2R:13579, Dm_2R:13612, DmDscam
2,038Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
Q0E9I4Q0E9I4_DROME
Down syndrome cell adhesion molecul...
Dscam1 43Bc, CT39257, Dm_2R:13579, Dm_2R:13612, DmDscam
2,031Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
Q0E9J0Q0E9J0_DROME
Down syndrome cell adhesion molecul...
Dscam1 43Bc, CT39257, Dm_2R:13579, Dm_2R:13612, DmDscam
2,035Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
Q0E9H8Q0E9H8_DROME
Down syndrome cell adhesion molecul...
Dscam1 43Bc, CT39257, Dm_2R:13579, Dm_2R:13612, DmDscam
2,031Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
Q0E9L0Q0E9L0_DROME
Down syndrome cell adhesion molecul...
Dscam1 43Bc, CT39257, Dm_2R:13579, Dm_2R:13612, DmDscam
2,022Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
Q0E9K4Q0E9K4_DROME
Down syndrome cell adhesion molecul...
Dscam1 43Bc, CT39257, Dm_2R:13579, Dm_2R:13612, DmDscam
2,031Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
Q0E9J9Q0E9J9_DROME
Down syndrome cell adhesion molecul...
Dscam1 43Bc, CT39257, Dm_2R:13579, Dm_2R:13612, DmDscam
2,032Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
Q0E9K9Q0E9K9_DROME
Down syndrome cell adhesion molecul...
Dscam1 43Bc, CT39257, Dm_2R:13579, Dm_2R:13612, DmDscam
2,032Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
Q0E9H6Q0E9H6_DROME
Down syndrome cell adhesion molecul...
Dscam1 43Bc, CT39257, Dm_2R:13579, Dm_2R:13612, DmDscam
2,032Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
Q0E9K7Q0E9K7_DROME
Down syndrome cell adhesion molecul...
Dscam1 43Bc, CT39257, Dm_2R:13579, Dm_2R:13612, DmDscam
2,017Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
There are more potential isoformsShow all

Sequence databases

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EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

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DDBJi
Links Updated
AE013599 Genomic DNA Translation: ABI31053.1

NCBI Reference Sequences

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RefSeqi
NP_001036502.1, NM_001043037.1

Genome annotation databases

Ensembl metazoan genome annotation project

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EnsemblMetazoai
FBtr0111067; FBpp0110361; FBgn0033159

Database of genes from NCBI RefSeq genomes

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GeneIDi
35652

UCSC genome browser

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UCSCi
CG17800-RAU d. melanogaster

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE013599 Genomic DNA Translation: ABI31053.1
RefSeqiNP_001036502.1, NM_001043037.1

3D structure databases

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Protein Data Bank Europe

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PDBei

Protein Data Bank RCSB

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RCSB PDBi

Protein Data Bank Japan

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PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
4X9IX-ray2.90A/B34-427[»]
4XB8X-ray3.20A/B34-427[»]
SMRiQ0E9L5
ModBaseiSearch...

Proteomic databases

PRIDEiQ0E9L5

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiFBtr0111067; FBpp0110361; FBgn0033159
GeneIDi35652
UCSCiCG17800-RAU d. melanogaster

Organism-specific databases

Comparative Toxicogenomics Database

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CTDi
35652
FlyBaseiFBgn0033159 Dscam1

Miscellaneous databases

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
35652

Gene expression databases

BgeeiFBgn0033159 Expressed in 25 organ(s), highest expression level in embryo
ExpressionAtlasiQ0E9L5 baseline and differential
GenevisibleiQ0E9L5 DM

Family and domain databases

CDDicd00063 FN3, 6 hits
Gene3Di2.60.40.10, 16 hits
InterProiView protein in InterPro
IPR021012 Dscam_C
IPR003961 FN3_dom
IPR036116 FN3_sf
IPR007110 Ig-like_dom
IPR036179 Ig-like_dom_sf
IPR013783 Ig-like_fold
IPR013098 Ig_I-set
IPR003599 Ig_sub
IPR003598 Ig_sub2
PfamiView protein in Pfam
PF12355 Dscam_C, 1 hit
PF00041 fn3, 6 hits
PF07679 I-set, 5 hits
SMARTiView protein in SMART
SM00060 FN3, 6 hits
SM00409 IG, 10 hits
SM00408 IGc2, 10 hits
SUPFAMiSSF48726 SSF48726, 9 hits
SSF49265 SSF49265, 3 hits
PROSITEiView protein in PROSITE
PS50853 FN3, 6 hits
PS50835 IG_LIKE, 9 hits

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ0E9L5_DROME
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q0E9L5
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: October 17, 2006
Last sequence update: October 17, 2006
Last modified: July 31, 2019
This is version 115 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
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