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Entry version 118 (16 Oct 2019)
Sequence version 1 (17 Oct 2006)
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Protein
Submitted name:

FI05595p

Gene

Dmel\CG30015

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
FI05595pImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Dmel\CG30015Imported
Synonyms:anon-EST:Posey2Imported, CG30015-RBImported, CG7699Imported, CG7701Imported
ORF Names:CG30015Imported, Dmel_CG30015Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDrosophila melanogaster (Fruit fly)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7227 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000803 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 2R

Organism-specific databases

Drosophila genome database

More...
FlyBasei
FBgn0050015 CG30015

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

PRoteomics IDEntifications database

More...
PRIDEi
Q0E9C6

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
FBgn0050015 Expressed in 30 organ(s), highest expression level in capitellum (Drosophila)

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q0E9C6 baseline and differential

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

Protein interaction database and analysis system

More...
IntActi
Q0E9C6, 7 interactors

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q0E9C6

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini708 – 936DUF4739InterPro annotationAdd BLAST229

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 207DisorderedSequence analysisAdd BLAST207
Regioni235 – 273DisorderedSequence analysisAdd BLAST39
Regioni323 – 408DisorderedSequence analysisAdd BLAST86
Regioni507 – 575DisorderedSequence analysisAdd BLAST69
Regioni762 – 802DisorderedSequence analysisAdd BLAST41
Regioni953 – 1005DisorderedSequence analysisAdd BLAST53
Regioni1029 – 1049DisorderedSequence analysisAdd BLAST21
Regioni1090 – 1156DisorderedSequence analysisAdd BLAST67
Regioni1169 – 1203DisorderedSequence analysisAdd BLAST35
Regioni1272 – 1386DisorderedSequence analysisAdd BLAST115
Regioni1423 – 1442DisorderedSequence analysisAdd BLAST20

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi42 – 74PolarSequence analysisAdd BLAST33
Compositional biasi75 – 89BasicSequence analysisAdd BLAST15
Compositional biasi93 – 156PolarSequence analysisAdd BLAST64
Compositional biasi157 – 179PolyampholyteSequence analysisAdd BLAST23
Compositional biasi180 – 202PolarSequence analysisAdd BLAST23
Compositional biasi235 – 255PolarSequence analysisAdd BLAST21
Compositional biasi345 – 387PolarSequence analysisAdd BLAST43
Compositional biasi507 – 559PolarSequence analysisAdd BLAST53
Compositional biasi560 – 575PolyampholyteSequence analysisAdd BLAST16
Compositional biasi762 – 784PolarSequence analysisAdd BLAST23
Compositional biasi786 – 802PolyampholyteSequence analysisAdd BLAST17
Compositional biasi964 – 1004PolarSequence analysisAdd BLAST41
Compositional biasi1090 – 1129PolarSequence analysisAdd BLAST40
Compositional biasi1133 – 1156PolyampholyteSequence analysisAdd BLAST24
Compositional biasi1275 – 1301PolarSequence analysisAdd BLAST27
Compositional biasi1302 – 1319PolyampholyteSequence analysisAdd BLAST18
Compositional biasi1321 – 1354PolarSequence analysisAdd BLAST34
Compositional biasi1361 – 1385PolarSequence analysisAdd BLAST25

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410J4AM Eukaryota
ENOG41126DN LUCA

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR031764 DUF4739

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF15893 DUF4739, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show allAlign All

Q0E9C6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSSGLMSCVR ENSPPLESEL DASCAGGPLS LPAGRAHPHT HGATSTPISS
60 70 80 90 100
PGNDAHQSPT AEHPNQQQQQ QQQKRRRFHP LRNLRRIFRR RTINSSTDSP
110 120 130 140 150
ASCQSPGPGS CNTLPPPASS SSEKNLRSGI ASPTGSPLNP QQLKENYQTQ
160 170 180 190 200
SLPKSKSYGS HRDELLSVLL GKKRASKQDH SQVAVQPDSQ AQSQSPQEAM
210 220 230 240 250
YQAQRQHGGV AVFPDSLVLN RSSYFAEQRI QQRHLRSVGD SSQELESNLG
260 270 280 290 300
LGSGSGSGSG AGGAADISDS QRSLSEGRLL DVDGDYSRDT LSQSHDSVFS
310 320 330 340 350
ESATASSLSI VLKAELTDVL RKRRNRPDAS DEDLGLPRSP ASPQRRAGGG
360 370 380 390 400
TSSRNTSGVG HQSRGHQSEV SSLSLHSVNS AEVETEDSQS SHQYRHHSRV
410 420 430 440 450
STSSSISMGS DILRSHHEDD VDAVGGERHR LSHAAAKHKM AIRPVKKKGP
460 470 480 490 500
TRQHRMTLET SIPEANEDVL KISPGLRAVH EADLKIKTRS LPPKTLTAIA
510 520 530 540 550
PPVQANAASS VTTKRTNTIE QSSTITSTTK TTSSSSTTSQ MFGLRGLTSK
560 570 580 590 600
SNALLENRGE SSTDGDDFLA NEREKENESG FLRRLIHRNS KRSIARANDG
610 620 630 640 650
VEDTDSSQSV AKKLQISTSC LEAAARDAVQ VPDKSRSATS HEQHIQETRQ
660 670 680 690 700
TIKREIHNEG KHGLNAMVSN YGVHPHPPTA LKPKSGPAAR QRYMPKELGA
710 720 730 740 750
APLEKITSGN DVTNLLSKSS RGNDTFQSTT LVREQQNKVE TSTHFERKPR
760 770 780 790 800
IVGLSAFQQK LSRSSDSVGQ HSSSSNSLET STDEPSPLYY EEKQRKTIEK
810 820 830 840 850
SRSFRNYEDE AVDSTAVHNN MPSLPDLSLS FRVPAYHKQA PQSPCSPISS
860 870 880 890 900
NAKCVSLGFE INDNKLLQSR AESTGQLPSA AKISPQKAAS TKLIVSSPGS
910 920 930 940 950
ADISKIEQNI DLIVKSPLVS VLRKSGNVAD KLPKEQTAPT KQRPKLLDLG
960 970 980 990 1000
AKMTAPAANP SPSPASPLTK SAKLSNSPPT TPAKGQGSSN SSRRNSSNVE
1010 1020 1030 1040 1050
NNGEPEFMKI QLNRVDQARL HNKTNHLVLA KNFKSPTERS QSNDDLSFRR
1060 1070 1080 1090 1100
SSEENLAGIE IVEHPQPKPL SPAIRPTALE PSLSRQLKSV SATSMRNSYG
1110 1120 1130 1140 1150
SSSEGLATPV TPVTTPSTPK SNGFSKSILS APKNVKEVKD TKEPVSPKEP
1160 1170 1180 1190 1200
VKSNRLSLED RKRLFLSEER TKSVEQRRKS ITKTESTAPP TPSVIPATPA
1210 1220 1230 1240 1250
IPVTPVTPTS PEIFEVNGNT SPTSNPVVLR KKSFASCNGN PSPSKDDPTP
1260 1270 1280 1290 1300
ELMKVFARRS LKVKDDDVVT LPQVQPAAPV SSNSKKLSPS GGGGQSVDSD
1310 1320 1330 1340 1350
KENQSNSEEK LDKLAPKSEP QATHHPSTNR NSVADFRNLN NNNNNHQQQQ
1360 1370 1380 1390 1400
KVPPKVVTYL PPIKTSNQGR NSLNNNISNG NGSARPAAER FSLQLKQANP
1410 1420 1430 1440 1450
TATTPTSPAA ATPVAAPTAT SAAATASVAP SKPIERSATV GEFKGIHQRR
1460
AEWEQRAKEA LK
Length:1,462
Mass (Da):157,566
Last modified:October 17, 2006 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i81068C0452A33C30
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A8DY97A8DY97_DROME
Uncharacterized protein, isoform C
CG7701 anon-EST:Posey2, CG7699, Dmel\CG30015, CG30015, Dmel_CG30015
1,510Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A8DY98A8DY98_DROME
Uncharacterized protein, isoform D
anon-EST:Posey2 CG7699, CG7701, Dmel\CG30015, CG30015, Dmel_CG30015
1,170Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
Q8T0M2Q8T0M2_DROME
GH22734p
CG7701 anon-EST:Posey2, CG7699, Dmel\CG30015, CG30015, Dmel_CG30015
1,263Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0B4KFA3A0A0B4KFA3_DROME
Uncharacterized protein, isoform F
Dmel\CG30015 anon-EST:Posey2, CG7699, CG7701, CG30015, Dmel_CG30015
1,475Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AE013599 Genomic DNA Translation: AAF58740.2
AE013599 Genomic DNA Translation: AAF58741.2
BT044230 mRNA Translation: ACH92295.1

NCBI Reference Sequences

More...
RefSeqi
NP_610621.2, NM_136777.4
NP_724980.1, NM_165802.3

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
FBtr0088242; FBpp0087337; FBgn0050015
FBtr0088243; FBpp0087338; FBgn0050015

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
36147

UCSC genome browser

More...
UCSCi
CG30015-RA d. melanogaster

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE013599 Genomic DNA Translation: AAF58740.2
AE013599 Genomic DNA Translation: AAF58741.2
BT044230 mRNA Translation: ACH92295.1
RefSeqiNP_610621.2, NM_136777.4
NP_724980.1, NM_165802.3

3D structure databases

SMRiQ0E9C6
ModBaseiSearch...

Protein-protein interaction databases

IntActiQ0E9C6, 7 interactors

Proteomic databases

PRIDEiQ0E9C6

Genome annotation databases

EnsemblMetazoaiFBtr0088242; FBpp0087337; FBgn0050015
FBtr0088243; FBpp0087338; FBgn0050015
GeneIDi36147
UCSCiCG30015-RA d. melanogaster

Organism-specific databases

FlyBaseiFBgn0050015 CG30015

Phylogenomic databases

eggNOGiENOG410J4AM Eukaryota
ENOG41126DN LUCA

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
CG30015 fly

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
36147

Gene expression databases

BgeeiFBgn0050015 Expressed in 30 organ(s), highest expression level in capitellum (Drosophila)
ExpressionAtlasiQ0E9C6 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR031764 DUF4739
PfamiView protein in Pfam
PF15893 DUF4739, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ0E9C6_DROME
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q0E9C6
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: October 17, 2006
Last sequence update: October 17, 2006
Last modified: October 16, 2019
This is version 118 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
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