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UniProtKB - Q0DK16 (NIP13_ORYSJ)
Protein
Aquaporin NIP1-3
Gene
NIP1-3
Organism
Oryza sativa subsp. japonica (Rice)
Status
Functioni
Aquaporins facilitate the transport of water and small neutral solutes across cell membranes.
By similarityGO - Molecular functioni
- channel activity Source: InterPro
Keywordsi
Biological process | Transport |
Names & Taxonomyi
Protein namesi | Recommended name: Aquaporin NIP1-3Alternative name(s): NOD26-like intrinsic protein 1-3 OsNIP1;3 |
Gene namesi | Name:NIP1-3 Ordered Locus Names:Os05g0205000, LOC_Os05g11560 ORF Names:OSJNBb0115F21.2 |
Organismi | Oryza sativa subsp. japonica (Rice) |
Taxonomic identifieri | 39947 [NCBI] |
Taxonomic lineagei | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliopsida › Liliopsida › Poales › Poaceae › BOP clade › Oryzoideae › Oryzeae › Oryzinae › Oryza › Oryza sativa |
Proteomesi |
|
Subcellular locationi
Other locations
- Membrane Curated; Multi-pass membrane protein Curated
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 56 – 76 | Helical; Name=1Sequence analysisAdd BLAST | 21 | |
Transmembranei | 84 – 104 | Helical; Name=2Sequence analysisAdd BLAST | 21 | |
Transmembranei | 131 – 153 | Helical; Name=3Sequence analysisAdd BLAST | 23 | |
Transmembranei | 172 – 192 | Helical; Name=4Sequence analysisAdd BLAST | 21 | |
Transmembranei | 200 – 220 | Helical; Name=5Sequence analysisAdd BLAST | 21 | |
Transmembranei | 239 – 259 | Helical; Name=6Sequence analysisAdd BLAST | 21 |
Keywords - Cellular componenti
MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000286028 | 1 – 286 | Aquaporin NIP1-3Add BLAST | 286 |
Proteomic databases
PaxDbi | Q0DK16 |
Family & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 44 | DisorderedSequence analysisAdd BLAST | 44 |
Motif
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Motifi | 113 – 115 | NPA 1 | 3 | |
Motifi | 225 – 227 | NPA 2 | 3 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 9 – 32 | Basic and acidic residuesSequence analysisAdd BLAST | 24 |
Domaini
Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).
Sequence similaritiesi
Belongs to the MIP/aquaporin (TC 1.A.8) family. NIP (TC 1.A.8.12) subfamily. [View classification]Curated
Keywords - Domaini
Repeat, Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | KOG0223, Eukaryota |
HOGENOMi | CLU_020019_3_1_1 |
InParanoidi | Q0DK16 |
OrthoDBi | 1152704at2759 |
Family and domain databases
CDDi | cd00333, MIP, 1 hit |
Gene3Di | 1.20.1080.10, 1 hit |
InterProi | View protein in InterPro IPR023271, Aquaporin-like IPR034294, Aquaporin_transptr IPR000425, MIP IPR022357, MIP_CS |
PANTHERi | PTHR45724, PTHR45724, 1 hit |
Pfami | View protein in Pfam PF00230, MIP, 1 hit |
PRINTSi | PR00783, MINTRINSICP |
SUPFAMi | SSF81338, SSF81338, 1 hit |
TIGRFAMsi | TIGR00861, MIP, 1 hit |
PROSITEi | View protein in PROSITE PS00221, MIP, 1 hit |
s (2+)i Sequence
Sequence statusi: Complete.
This entry describes 2 produced by isoformsialternative splicing. AlignAdd to basketThis entry has 2 described isoforms and 1 potential isoform that is computationally mapped.Show allAlign All
Isoform 1 (identifier: Q0DK16-1) [UniParc]FASTAAdd to basket
This isoform has been chosen as the sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry. canonicali
10 20 30 40 50
MAGGEHGVNG QHEETRAMEE GSRDHQARCE NSEQDGGSKS SSNNHPMFSV
60 70 80 90 100
QFAQKVIAEI LGTFFLIFAG CAAVAVNKRT GGTVTFPGIC ITWGLAVMVM
110 120 130 140 150
VYSVGHISGA HLNPAVTLAF ATCGRFPWRR VPAYAAAQVA GSAAASAALR
160 170 180 190 200
ALFGGAPEHF FGTAPAGSDV QSLAMEFIIT FYLMFVVSGV ATDNRAIGEL
210 220 230 240 250
AGLAVGATVL VNVLFAGPIS GASMNPARTI GPAIILGRYT GIWVYIAGPV
260 270 280
FGAVAGAWAY NLIRFTDKPL REITMTASFI RSTRRN
Computationally mapped potential isoform sequencesi
There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basketA0A0N7KKB4 | A0A0N7KKB4_ORYSJ | Os05g0205000 protein | Os05g0205000, OSNPB_050205000 | 88 | Annotation score: |
Sequence cautioni
The sequence BAF16807 differs from that shown. Reason: Erroneous gene model prediction.Curated
Alternative sequence
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Alternative sequenceiVSP_024949 | 218 – 220 | PIS → YTS in isoform 2. Curated | 3 | |
Alternative sequenceiVSP_024950 | 221 – 286 | Missing in isoform 2. CuratedAdd BLAST | 66 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC135918 Genomic DNA Translation: AAV44140.1 AP008211 Genomic DNA Translation: BAF16807.1 Sequence problems. AP014961 Genomic DNA No translation available. |
RefSeqi | XP_015637523.1, XM_015782037.1 [Q0DK16-1] |
Genome annotation databases
GeneIDi | 4338071 |
KEGGi | osa:4338071 |
Keywords - Coding sequence diversityi
Alternative splicingSimilar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC135918 Genomic DNA Translation: AAV44140.1 AP008211 Genomic DNA Translation: BAF16807.1 Sequence problems. AP014961 Genomic DNA No translation available. |
RefSeqi | XP_015637523.1, XM_015782037.1 [Q0DK16-1] |
3D structure databases
AlphaFoldDBi | Q0DK16 |
SMRi | Q0DK16 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 4530.OS05T0205050-00 |
Proteomic databases
PaxDbi | Q0DK16 |
Genome annotation databases
GeneIDi | 4338071 |
KEGGi | osa:4338071 |
Phylogenomic databases
eggNOGi | KOG0223, Eukaryota |
HOGENOMi | CLU_020019_3_1_1 |
InParanoidi | Q0DK16 |
OrthoDBi | 1152704at2759 |
Family and domain databases
CDDi | cd00333, MIP, 1 hit |
Gene3Di | 1.20.1080.10, 1 hit |
InterProi | View protein in InterPro IPR023271, Aquaporin-like IPR034294, Aquaporin_transptr IPR000425, MIP IPR022357, MIP_CS |
PANTHERi | PTHR45724, PTHR45724, 1 hit |
Pfami | View protein in Pfam PF00230, MIP, 1 hit |
PRINTSi | PR00783, MINTRINSICP |
SUPFAMi | SSF81338, SSF81338, 1 hit |
TIGRFAMsi | TIGR00861, MIP, 1 hit |
PROSITEi | View protein in PROSITE PS00221, MIP, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | NIP13_ORYSJ | |
Accessioni | Q0DK16Primary (citable) accession number: Q0DK16 Secondary accession number(s): Q5W6J2 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | May 1, 2007 |
Last sequence update: | May 1, 2007 | |
Last modified: | May 25, 2022 | |
This is version 94 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Plant Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Oryza sativa (rice)
Index of Oryza sativa entries and their corresponding gene designations - SIMILARITY comments
Index of protein domains and families