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Protein

Energy-coupling factor transporter ATP-binding protein EcfA

Gene

ecfA

Organism
Syntrophomonas wolfei subsp. wolfei (strain DSM 2245B / Goettingen)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.UniRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi36 – 43ATPUniRule annotation8

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase
Biological processTransport
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciSWOL335541:G1G78-2402-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Energy-coupling factor transporter ATP-binding protein EcfAUniRule annotation (EC:3.6.3.-UniRule annotation)
Short name:
ECF transporter A component EcfAUniRule annotation
Gene namesi
Name:ecfAUniRule annotation
Synonyms:cbiO
Ordered Locus Names:Swol_2302
OrganismiSyntrophomonas wolfei subsp. wolfei (strain DSM 2245B / Goettingen)
Taxonomic identifieri335541 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesSyntrophomonadaceaeSyntrophomonas
Proteomesi
  • UP000001968 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002880171 – 273Energy-coupling factor transporter ATP-binding protein EcfAAdd BLAST273

Interactioni

Subunit structurei

Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).UniRule annotation

Protein-protein interaction databases

STRINGi335541.Swol_2302

Structurei

3D structure databases

ProteinModelPortaliQ0AUL1
SMRiQ0AUL1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini2 – 237ABC transporterUniRule annotationAdd BLAST236

Sequence similaritiesi

Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4108JJB Bacteria
COG1122 LUCA
KOiK16786
OMAiHVTHSME
OrthoDBiPOG091H01OM

Family and domain databases

InterProiView protein in InterPro
IPR003593 AAA+_ATPase
IPR003439 ABC_transporter-like
IPR017871 ABC_transporter_CS
IPR015856 ABC_transpr_CbiO/EcfA_su
IPR030947 EcfA_1
IPR027417 P-loop_NTPase
PANTHERiPTHR43553:SF4 PTHR43553:SF4, 1 hit
PfamiView protein in Pfam
PF00005 ABC_tran, 1 hit
SMARTiView protein in SMART
SM00382 AAA, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
TIGRFAMsiTIGR04520 ECF_ATPase_1, 1 hit
PROSITEiView protein in PROSITE
PS00211 ABC_TRANSPORTER_1, 1 hit
PS50893 ABC_TRANSPORTER_2, 1 hit
PS51246 CBIO, 1 hit

Sequencei

Sequence statusi: Complete.

Q0AUL1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MISIRDLTYF YPEEDLPALK NISLDIRENE FLVILGRNGS GKSTLARLLN
60 70 80 90 100
GLLLPSQGKV EVDGWNTADA NQIQLIRQRV GLLFSNPDNQ LISNQVEEDV
110 120 130 140 150
AFGPENLGLN TAEIRRRVND SLRLVSMESY KNSAPAFLSG GQKQKIAIAG
160 170 180 190 200
VMAMKPRYLV LDEALSMIDP RGKREIMESI RSLHKTEGVV VIMITHDLEE
210 220 230 240 250
AREADRVVVL EEGEVKTIST PEELFPSRAS LLALGLAPLE ISHIIAEINR
260 270
QGILLSTDIL DIDKLVEEIC HFV
Length:273
Mass (Da):30,381
Last modified:October 17, 2006 - v1
Checksum:iF1ED33CC678701F0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000448 Genomic DNA Translation: ABI69593.1
RefSeqiWP_011641677.1, NC_008346.1

Genome annotation databases

EnsemblBacteriaiABI69593; ABI69593; Swol_2302
KEGGiswo:Swol_2302

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000448 Genomic DNA Translation: ABI69593.1
RefSeqiWP_011641677.1, NC_008346.1

3D structure databases

ProteinModelPortaliQ0AUL1
SMRiQ0AUL1
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi335541.Swol_2302

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABI69593; ABI69593; Swol_2302
KEGGiswo:Swol_2302

Phylogenomic databases

eggNOGiENOG4108JJB Bacteria
COG1122 LUCA
KOiK16786
OMAiHVTHSME
OrthoDBiPOG091H01OM

Enzyme and pathway databases

BioCyciSWOL335541:G1G78-2402-MONOMER

Family and domain databases

InterProiView protein in InterPro
IPR003593 AAA+_ATPase
IPR003439 ABC_transporter-like
IPR017871 ABC_transporter_CS
IPR015856 ABC_transpr_CbiO/EcfA_su
IPR030947 EcfA_1
IPR027417 P-loop_NTPase
PANTHERiPTHR43553:SF4 PTHR43553:SF4, 1 hit
PfamiView protein in Pfam
PF00005 ABC_tran, 1 hit
SMARTiView protein in SMART
SM00382 AAA, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
TIGRFAMsiTIGR04520 ECF_ATPase_1, 1 hit
PROSITEiView protein in PROSITE
PS00211 ABC_TRANSPORTER_1, 1 hit
PS50893 ABC_TRANSPORTER_2, 1 hit
PS51246 CBIO, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiECFA_SYNWW
AccessioniPrimary (citable) accession number: Q0AUL1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 29, 2007
Last sequence update: October 17, 2006
Last modified: November 7, 2018
This is version 81 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
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Main funding by: National Institutes of Health

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