Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

30S ribosomal protein S12

Gene

rpsL

Organism
Syntrophomonas wolfei subsp. wolfei (strain DSM 2245B / Goettingen)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

With S4 and S5 plays an important role in translational accuracy.UniRule annotation
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein, RNA-binding, rRNA-binding, tRNA-binding

Enzyme and pathway databases

BioCyciSWOL335541:G1G78-2438-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
30S ribosomal protein S12UniRule annotation
Gene namesi
Name:rpsLUniRule annotation
Ordered Locus Names:Swol_2338
OrganismiSyntrophomonas wolfei subsp. wolfei (strain DSM 2245B / Goettingen)
Taxonomic identifieri335541 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesSyntrophomonadaceaeSyntrophomonas
Proteomesi
  • UP000001968 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002636001 – 12530S ribosomal protein S12Add BLAST125

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei893-methylthioaspartic acidBy similarity1

Keywords - PTMi

Methylation

Proteomic databases

PRIDEiQ0AUH5

Interactioni

Subunit structurei

Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.UniRule annotation

Protein-protein interaction databases

STRINGi335541.Swol_2338

Structurei

3D structure databases

ProteinModelPortaliQ0AUH5
SMRiQ0AUH5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the universal ribosomal protein uS12 family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4108UKE Bacteria
COG0048 LUCA
HOGENOMiHOG000040063
KOiK02950
OMAiKRGVCTA
OrthoDBiPOG091H025P

Family and domain databases

CDDicd03368 Ribosomal_S12, 1 hit
HAMAPiMF_00403_B Ribosomal_S12_B, 1 hit
InterProiView protein in InterPro
IPR012340 NA-bd_OB-fold
IPR006032 Ribosomal_S12/S23
IPR005679 Ribosomal_S12_bac
PANTHERiPTHR11652 PTHR11652, 1 hit
PfamiView protein in Pfam
PF00164 Ribosom_S12_S23, 1 hit
PIRSFiPIRSF002133 Ribosomal_S12/S23, 1 hit
PRINTSiPR01034 RIBOSOMALS12
SUPFAMiSSF50249 SSF50249, 1 hit
TIGRFAMsiTIGR00981 rpsL_bact, 1 hit
PROSITEiView protein in PROSITE
PS00055 RIBOSOMAL_S12, 1 hit

Sequencei

Sequence statusi: Complete.

Q0AUH5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPTINQLVRK GREKGEQKST APALKSCPQK RGVCTRVYTT TPKKPNSALR
60 70 80 90 100
KIARVRLTNG IEVTAYIPGI GHNLQEHSVV LIRGGRVKDL PGVRYHIIRG
110 120
TLDASGVQKR NQGRSKYGTK RPKKK
Length:125
Mass (Da):13,895
Last modified:October 17, 2006 - v1
Checksum:iF8253CEEF5F81F44
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000448 Genomic DNA Translation: ABI69629.1
RefSeqiWP_011641713.1, NC_008346.1

Genome annotation databases

EnsemblBacteriaiABI69629; ABI69629; Swol_2338
KEGGiswo:Swol_2338

Similar proteinsi

Entry informationi

Entry nameiRS12_SYNWW
AccessioniPrimary (citable) accession number: Q0AUH5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 12, 2006
Last sequence update: October 17, 2006
Last modified: February 28, 2018
This is version 72 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Ribosomal proteins
    Ribosomal proteins families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health