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Protein

Protein TIC 214

Gene

TIC214

Organism
Platanus occidentalis (Sycamore) (American plane tree)
Status
Reviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Involved in protein precursor import into chloroplasts. May be part of an intermediate translocation complex acting as a protein-conducting channel at the inner envelope.By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processProtein transport, Transport

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Protein TIC 214By similarity
Alternative name(s):
Translocon at the inner envelope membrane of chloroplasts 214By similarity
Short name:
AtTIC214By similarity
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:TIC214By similarity
Synonyms:ycf1
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates if the gene coding for the protein originates from the hydrogenosome, the mitochondrion, the nucleomorph, different plastids or a plasmid. The absence of this section means that the gene is located in one of the main chromosomal element(s).<p><a href='/help/encoded_on' target='_top'>More...</a></p>Encoded oniPlastid; Chloroplast
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiPlatanus occidentalis (Sycamore) (American plane tree)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri4403 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsProtealesPlatanaceaePlatanus

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei18 – 38HelicalSequence analysisAdd BLAST21
Transmembranei64 – 84HelicalSequence analysisAdd BLAST21
Transmembranei90 – 110HelicalSequence analysisAdd BLAST21
Transmembranei126 – 146HelicalSequence analysisAdd BLAST21
Transmembranei174 – 194HelicalSequence analysisAdd BLAST21
Transmembranei230 – 250HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Chloroplast, Membrane, Plastid, Plastid inner membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002626251 – 1915Protein TIC 214Add BLAST1915

Proteomic databases

PRoteomics IDEntifications database

More...
PRIDEi
Q09FY8

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Part of the Tic complex.By similarity

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the TIC214 family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR008896 TIC214

The PANTHER Classification System

More...
PANTHERi
PTHR33163 PTHR33163, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF05758 Ycf1, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q09FY8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MILKSFLLGN LLSLCMKIIN SVVVVGLYYG FLTTFSIGPS YLFLLRARVM
60 70 80 90 100
EEGTEKEVSA TTGFITGQLM MFISIYYAPL HLALGRPHTI TVLVLPYLLF
110 120 130 140 150
HFFWHNHKYF LNINYGSTIR NSIRNLNIQC VFLNNLIFPL FNHFILPSST
160 170 180 190 200
LARLINIYMF QCNNKMLFVT SSFVGWLIGH ILFMKWVELV LIWIRQNHFF
210 220 230 240 250
RSNALFIRSN VLIVPKKNLV PELRNSMARI FSILLFITCI YYLGRMPSTL
260 270 280 290 300
VTKKMKETSK MKQMGQSEEE TDVEIETTSE TKETKEEQEG STEEDPSPSL
310 320 330 340 350
YSEEKEDPDK IDETEEIRVN GNEKSKDEFH FRFKKTCYKY KNSPVFQNFY
360 370 380 390 400
LDGNQENSKL EILKYEKKNL FWFQKPLVTL LFDYKRWNRP LRYIKNNQLE
410 420 430 440 450
NAVRNEMSQY FFYTCQSDGK QRISFTYPPS LSTFWEMIQR KMSLYTTEKL
460 470 480 490 500
SPEELYNHWV YTNEQKRNNV SKEFINRIEA LDKGSLTLDV LEKRTRLCND
510 520 530 540 550
KTEQQCLPKV YDPFLNGPYR GTIKKVSSSS IMNDYLITSI ENSIEKLWIN
560 570 580 590 600
KIHGILPTDY REFEQKEKID TFDGKSLSTD IFHFLTPISK FAGESTTSLN
610 620 630 640 650
WKGLPLLAEQ ERNYSKDQAK YLKFLFAAVT TDPNNQIIRN KSIVINEICK
660 670 680 690 700
KVPRWSYKLI DDLEQQEGEY EEESAEDHQI RSRKAKRVVI FTDNEPDTNT
710 720 730 740 750
HTNTNNTSDR DEVEEVALIR YSQQPDFRRD IIKGSMRAQR RKIVIWELFQ
760 770 780 790 800
ANVHSPLFLD KIDKTFFFSF DISEMTKFIF RNCMGKNTKL KTSDPEEKEK
810 820 830 840 850
KEKKEENERI AVAETWDSIL FAQPIRGSML VTQSILRKYI VLPLLIIAKN
860 870 880 890 900
TARILLFQFP EWFEDWEEWN REIHVKCTYN GVPLSETEFP RNWLKDGIQI
910 920 930 940 950
KILFPLCLKP WHRFKLRSHH RGPMKKKGKK YNFCFLTVWG METELPFGSP
960 970 980 990 1000
RNQPSFFEPI LKELEKKIRK VKNQFFRILR VVKERTKWFL TVLKEKKRWV
1010 1020 1030 1040 1050
IEIILFIKRI MKELAKINPI LLFGLKEVYE SSENKNRKNS QNSITIISNQ
1060 1070 1080 1090 1100
IIHESPIRIR STDWTNYYYS LTEKKMKNLA DRTSTIRNQI ERITKDKKKI
1110 1120 1130 1140 1150
FLTPEINISP KKMSCGDKRS ESLKSFWEIV KKRSIRLIRK WHFFLKFVIE
1160 1170 1180 1190 1200
KIYLLCIINI PRINAQLFLE STKKILDKYI YNYNDETNQE EIDEINQKKI
1210 1220 1230 1240 1250
HFISTIKKSL FHISNNNSQI FCDLSSLSQA YVFYKLSQTK VINKYHLRSV
1260 1270 1280 1290 1300
LEYHERSLFL KDRIKDYFRT QGIFHFESRH KKLRNSGMND WKNWLKGHYQ
1310 1320 1330 1340 1350
YQYDLSQTRW ARLVPQKWQN RVNQRRTTQN KDSKKLGSYE KDQLIHYQKQ
1360 1370 1380 1390 1400
NDYAVELLSN KKEKLKKHYG YDLLSHKYIN YENKKDLYIY RSPLQVNEGR
1410 1420 1430 1440 1450
EITYNYTTHK LESFCVLGGI PIRDYLGEDY IIETDKNPDR KYFDWGILHF
1460 1470 1480 1490 1500
CLRKEVDIDT WTNMDTEASI NKKTKTGTNY SQIVEKINKK DLFMIHEEIN
1510 1520 1530 1540 1550
PSNQKKKPFD WMGMNEEILN RTISNLELWF VPEFLLLYDT YKMKPWGIPI
1560 1570 1580 1590 1600
KLLLVNLNGN ENVSENKNIN RKQKKNLPLS SNKNKKKSLE LENRNQEEKE
1610 1620 1630 1640 1650
SSSQGDLGSN AQNQGNLGPN AQNQGNLGSV LPNQQKNLEE DYAGSDIKKV
1660 1670 1680 1690 1700
RKKKQFKSKA EVELDLLLKK YLLFQLRWNG SLNQRILNNI KIYCFLLRLI
1710 1720 1730 1740 1750
NPKEITISSI QKGEMSLGIM LIKRDLTFTE LIKRGIFIIE PVRLSIKWDG
1760 1770 1780 1790 1800
QFIMYQTIGI SLVHKSKHQT NQRYREKRCI DKNHFEGFIA RHENMLGNGD
1810 1820 1830 1840 1850
ENHYDLLVPE NISSPRRRRE LRILTCFHFL NGNVLDRNPV FCNGNNVKNC
1860 1870 1880 1890 1900
GQFLNEDKHL DRDTNKLINM KLKFFLWPNY RLEDLACMNR YWFDTNNGSR
1910
FSMSRIHMYP RLKIS
Length:1,915
Mass (Da):227,739
Last modified:October 17, 2006 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iFE63C74A3FD8C7C2
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
DQ923116 Genomic DNA Translation: ABI49837.1

NCBI Reference Sequences

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RefSeqi
YP_740623.1, NC_008335.1

Genome annotation databases

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
4271362

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DQ923116 Genomic DNA Translation: ABI49837.1
RefSeqiYP_740623.1, NC_008335.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

Proteomic databases

PRIDEiQ09FY8

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi4271362

Family and domain databases

InterProiView protein in InterPro
IPR008896 TIC214
PANTHERiPTHR33163 PTHR33163, 1 hit
PfamiView protein in Pfam
PF05758 Ycf1, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiTI214_PLAOC
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q09FY8
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 28, 2006
Last sequence update: October 17, 2006
Last modified: November 7, 2018
This is version 31 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families
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