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Entry version 132 (16 Oct 2019)
Sequence version 2 (10 Jan 2006)
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Protein
Submitted name:

SSD domain-containing protein

Gene

ptr-6

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

  • molting cycle, collagen and cuticulin-based cuticle Source: WormBase

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
SSD domain-containing proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ptr-6Imported
ORF Names:C54A12.1Imported, CELE_C54A12.1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiCaenorhabditis elegansImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri6239 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditinaRhabditomorphaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001940 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome II

Organism-specific databases

WormBase

More...
WormBasei
C54A12.1 ; CE39341 ; WBGene00004221 ; ptr-6

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei27 – 49HelicalSequence analysisAdd BLAST23
Transmembranei301 – 322HelicalSequence analysisAdd BLAST22
Transmembranei342 – 363HelicalSequence analysisAdd BLAST22
Transmembranei370 – 393HelicalSequence analysisAdd BLAST24
Transmembranei413 – 436HelicalSequence analysisAdd BLAST24
Transmembranei448 – 473HelicalSequence analysisAdd BLAST26
Transmembranei585 – 605HelicalSequence analysisAdd BLAST21
Transmembranei845 – 868HelicalSequence analysisAdd BLAST24
Transmembranei888 – 909HelicalSequence analysisAdd BLAST22
Transmembranei921 – 947HelicalSequence analysisAdd BLAST27

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q09938

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q09938

PeptideAtlas

More...
PeptideAtlasi
Q09938

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
WBGene00004221 Expressed in 4 organ(s), highest expression level in multi-cellular organism

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini302 – 473SSDInterPro annotationAdd BLAST172

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni505 – 553DisorderedSequence analysisAdd BLAST49

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili947 – 967Sequence analysisAdd BLAST21

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi515 – 543PolyampholyteSequence analysisAdd BLAST29

Keywords - Domaini

Coiled coilSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1934 Eukaryota
ENOG410XRZ4 LUCA

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000017068

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q09938

Identification of Orthologs from Complete Genome Data

More...
OMAi
ERTFEWN

Database of Orthologous Groups

More...
OrthoDBi
210960at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q09938

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR003392 Ptc/Disp
IPR000731 SSD

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF02460 Patched, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50156 SSD, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q09938-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MRCRIPTLDK KLEKVFAWYT KHLLVDYYYV FLIAPVILTA ICSCGFYWIK
60 70 80 90 100
ELTLLDARKL YTPVSAPSWK EEQVFSELWP VKSYEFLPER TFQWNRYLYL
110 120 130 140 150
VVHGRPYENG TYPNILEGSY LNDIAKIEEE LVTNVSFPRE AALEDNPALM
160 170 180 190 200
RKRHLNETEI EENRNITITF KDVCMNWYGD CYREKNVIEL LKRRHELNKR
210 220 230 240 250
GISVTFPQVN QEGTPIYIAF VIGGVDTYPN DTIKYARAMR LWYFLKFDDE
260 270 280 290 300
EQEQLAKFWE DTAEKFVRET YADHPTIQCH IKHSRIVDQG LTRNANRLKP
310 320 330 340 350
YFNVTIAVLV LFTAFYSVKW YFRMDHSWPL HIDWLRSKPM LALGGVLSSV
360 370 380 390 400
LAILSGIGLL LWFGMFFAEI TLIAPFLVLS IGVDDMFIAV AAWHNTEMKY
410 420 430 440 450
PGRSPKVMKK RMIEAMSESA VAIFITSFTD VLSFGAGTIT DIIAVQGFCA
460 470 480 490 500
MTAACMFFTF LYQITFFAAL MVISAKAQMS GRNSCMPCIT AGDIYTIEDG
510 520 530 540 550
SLQPNLKKKK SKSRKDAKAE KEKKDEAKND KNMEIEENAE NAEKSSYDSS
560 570 580 590 600
PDPSQIHIPV KSRGAMGHFF RDYYVPWLLN WKTKLFMFVT FIIYLGISVY
610 620 630 640 650
GICVMEQGLD YDKLLLHSDP LVEALKREIE LFHGGDQIEI AIQNCPNITI
660 670 680 690 700
AESRDRIELV AQEFENISYS LGGKGTSFWM REYKKYSNLT GSYLNDNRES
710 720 730 740 750
WIVGVYEWSQ LFAFYKLWSQ DFVWANESDY DTLELKSYRF RIGVHRLSTP
760 770 780 790 800
TDLVLITEEL RGVADRHPDL NIVTYQQSRA IADQLNVILS STITNDTLAM
810 820 830 840 850
FCMFCVALIF IPNPICALFI TFAMVTIDIG VIGFLSLWSV KLDPISMITI
860 870 880 890 900
IMSIGFSIEF SAHITHGFVS NDSNLSAFDR CVDAMEKLAW PVVHGSLSTI
910 920 930 940 950
LGVFVLAFID SYMVLVFFKT ISLVLIIGAW HALMLLPILL SMCIPVIERL
960 970 980
SDASKKASDR RRKLKENKNS VYAINLPVNV SS
Length:982
Mass (Da):112,732
Last modified:January 10, 2006 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iE5ED79E3A57D85E8
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

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DDBJi
Links Updated
BX284602 Genomic DNA Translation: CCD67999.1

Protein sequence database of the Protein Information Resource

More...
PIRi
T15830

NCBI Reference Sequences

More...
RefSeqi
NP_494986.2, NM_062585.4

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
C54A12.1.1; C54A12.1.1; WBGene00004221

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
173898

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
cel:CELE_C54A12.1

UCSC genome browser

More...
UCSCi
C54A12.1 c. elegans

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284602 Genomic DNA Translation: CCD67999.1
PIRiT15830
RefSeqiNP_494986.2, NM_062585.4

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Proteomic databases

EPDiQ09938
PaxDbiQ09938
PeptideAtlasiQ09938

Genome annotation databases

EnsemblMetazoaiC54A12.1.1; C54A12.1.1; WBGene00004221
GeneIDi173898
KEGGicel:CELE_C54A12.1
UCSCiC54A12.1 c. elegans

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
173898
WormBaseiC54A12.1 ; CE39341 ; WBGene00004221 ; ptr-6

Phylogenomic databases

eggNOGiKOG1934 Eukaryota
ENOG410XRZ4 LUCA
HOGENOMiHOG000017068
InParanoidiQ09938
OMAiERTFEWN
OrthoDBi210960at2759
PhylomeDBiQ09938

Gene expression databases

BgeeiWBGene00004221 Expressed in 4 organ(s), highest expression level in multi-cellular organism

Family and domain databases

InterProiView protein in InterPro
IPR003392 Ptc/Disp
IPR000731 SSD
PfamiView protein in Pfam
PF02460 Patched, 1 hit
PROSITEiView protein in PROSITE
PS50156 SSD, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ09938_CAEEL
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q09938
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: January 10, 2006
Last modified: October 16, 2019
This is version 132 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
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