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Protein

Putative phospholipid-transporting ATPase C24B11.12c

Gene

SPAC24B11.12c

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + H2O + phospholipid(Side 1) = ADP + phosphate + phospholipid(Side 2).

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei5694-aspartylphosphate intermediateBy similarity1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase
LigandATP-binding, Magnesium, Nucleotide-binding

Enzyme and pathway databases

ReactomeiR-SPO-936837 Ion transport by P-type ATPases

Names & Taxonomyi

Protein namesi
Recommended name:
Putative phospholipid-transporting ATPase C24B11.12c (EC:3.6.3.1)
Gene namesi
ORF Names:SPAC24B11.12c
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome I

Organism-specific databases

EuPathDBiFungiDB:SPAC24B11.12c
PomBaseiSPAC24B11.12c

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei109 – 129HelicalSequence analysisAdd BLAST21
Transmembranei135 – 155HelicalSequence analysisAdd BLAST21
Transmembranei457 – 477HelicalSequence analysisAdd BLAST21
Transmembranei501 – 521HelicalSequence analysisAdd BLAST21
Transmembranei1066 – 1086HelicalSequence analysisAdd BLAST21
Transmembranei1101 – 1121HelicalSequence analysisAdd BLAST21
Transmembranei1151 – 1171HelicalSequence analysisAdd BLAST21
Transmembranei1193 – 1213HelicalSequence analysisAdd BLAST21
Transmembranei1218 – 1238HelicalSequence analysisAdd BLAST21
Transmembranei1260 – 1280HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Cell membrane, Endoplasmic reticulum, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000462391 – 1402Putative phospholipid-transporting ATPase C24B11.12cAdd BLAST1402

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiQ09891
PaxDbiQ09891
PRIDEiQ09891

PTM databases

iPTMnetiQ09891

Interactioni

Protein-protein interaction databases

BioGridi278059, 29 interactors
STRINGi4896.SPAC24B11.12c.1

Structurei

3D structure databases

ProteinModelPortaliQ09891
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

HOGENOMiHOG000202528
InParanoidiQ09891
KOiK01530
OMAiPHRDLMN
OrthoDBiEOG092C0BQ4
PhylomeDBiQ09891

Family and domain databases

Gene3Di3.40.1110.10, 2 hits
3.40.50.1000, 2 hits
InterProiView protein in InterPro
IPR023299 ATPase_P-typ_cyto_dom_N
IPR018303 ATPase_P-typ_P_site
IPR023298 ATPase_P-typ_TM_dom_sf
IPR008250 ATPase_P-typ_transduc_dom_A_sf
IPR036412 HAD-like_sf
IPR023214 HAD_sf
IPR006539 P-type_ATPase_IV
IPR032631 P-type_ATPase_N
IPR001757 P_typ_ATPase
IPR032630 P_typ_ATPase_c
IPR026871 PLip_transp_ATPase
PANTHERiPTHR24092 PTHR24092, 1 hit
PTHR24092:SF34 PTHR24092:SF34, 1 hit
PfamiView protein in Pfam
PF16212 PhoLip_ATPase_C, 1 hit
PF16209 PhoLip_ATPase_N, 1 hit
SUPFAMiSSF56784 SSF56784, 2 hits
SSF81653 SSF81653, 2 hits
SSF81660 SSF81660, 2 hits
SSF81665 SSF81665, 3 hits
TIGRFAMsiTIGR01652 ATPase-Plipid, 1 hit
TIGR01494 ATPase_P-type, 2 hits
PROSITEiView protein in PROSITE
PS00154 ATPASE_E1_E2, 1 hit

Sequencei

Sequence statusi: Complete.

Q09891-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MESVEEKSKQ RRWLPNFKAL RLKVYRLADR LNIPLADAAR VELEEYDGSD
60 70 80 90 100
PQSLRGLQKL PRTLYFGLPL PDSELDDTGE AKRWFPRNKI RTAKYTPIDF
110 120 130 140 150
IPKNIFLQFQ NVANLFFLFL VILQSISIFG EQVNPGLAAV PLIVVVGITA
160 170 180 190 200
VKDAIEDFRR TMLDIHLNNT PTLRLSHYQN PNIRTEYISY FRRFKKRISA
210 220 230 240 250
LFRVFLAKQE EKKRAKRLND AVPLEDMAGS ESRPSYDSIF RESFEAKRSF
260 270 280 290 300
EDSKGKVPLS ALDGTATILQ SRPMDIIDYE AEATGECHFK KTYWKDVRVG
310 320 330 340 350
DFVKVMDNDE IPADIVIINS SDPEGICYIE TKNLDGETNL KMRHALTCGK
360 370 380 390 400
NVVDEASCER CRFWIESEPP HANLYEYNGA CKSFVHSEAG GSDTSQTVSE
410 420 430 440 450
PISLDSMLLR GCVLRNTKWV IGVVVFTGDD TKIMLNSGAP PLKRSRITRN
460 470 480 490 500
LNWNVYLNFI ILFSMCFVCA VVEGIAWRGH SRSSYYFEFG SIGGSPAKDG
510 520 530 540 550
VVTFFTGVIL FQNLVPISLY ISIEIVKTIQ AIFIYFDKDM YYKKLKYACT
560 570 580 590 600
PKSWNISDDL GQVEYIFSDK TGTLTQNVME FKKCTINGVA YGEAFTEAMA
610 620 630 640 650
GMAKREGKDT EELTLQKQSF IERDRMQMIS QMRNMHDNKY LVDDNLTFIS
660 670 680 690 700
SQFVHDLAGK AGEEQSLACY EFFLALALCH SVVADRVGDR IVYKAQSPDE
710 720 730 740 750
AALVGTARDV GFVFLDQRRD IMVTRALGET QRFKLMDTIE FSSARKRMSV
760 770 780 790 800
IVKGPDNRYV LICKGADSII FERLEPNEQV ELRKTTSEHL RIFALEGLRT
810 820 830 840 850
LCIAKRELTE EEYYEWKEKY DIAASAIENR EEQIEEVADL IESHLTLLGG
860 870 880 890 900
TAIEDRLQEG VPDSIALLAQ AGIKLWVLTG DKMETAINIG FSCNLLDAGM
910 920 930 940 950
DMIKFDVDQE VSTPELEVIL ADYLYRYFGL SGSVEELEAA KKDHDTPSGS
960 970 980 990 1000
HALVIDGSVL KRVLDGPMRT KFLLLCKRCK AVLCCRVSPA QKADVVQLVR
1010 1020 1030 1040 1050
ESLEVMTLAI GDGANDVAMI QKADIGVGIV GEEGRAAAMS ADYAIGQFRF
1060 1070 1080 1090 1100
LSKLVLVHGR WDYNRVAEMV NNFFYKSVVW TFTLFWYQIY NNFDANYLFD
1110 1120 1130 1140 1150
YTYVMLFNLI FSSLPVIVMG VYDQDVNADL SLRIPQLYKR GILQLNSARK
1160 1170 1180 1190 1200
IFIGYMLDGF YQSVICFFFS FLVINNVTTA AQNGRDTMAV QDLGVYVAAP
1210 1220 1230 1240 1250
TIMVVDTYVI LNQSNWDVFS IGLWALSCLT FWFWTGVYSQ SLYTYEFYKS
1260 1270 1280 1290 1300
ASRIFRTPNF WAVLCGTIVS CLFPKFLFMT TQKLFWPYDV DIIRESYRTK
1310 1320 1330 1340 1350
RLHELDEEEE IENAEQSPDW ASSTLQVPFN ASSSSLATPK KEPLRLDTNS
1360 1370 1380 1390 1400
LTLTSSMPRS FTPSYTPSFL EGSPVFSDEI LNRGEYMPHR GSISSSEQPL

RP
Length:1,402
Mass (Da):159,356
Last modified:February 1, 1996 - v1
Checksum:iE8495A7598B3020B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329670 Genomic DNA Translation: CAA91777.1
AB027875 Genomic DNA Translation: BAA87179.1
PIRiT38339 S62557
RefSeqiNP_592849.1, NM_001018250.2

Genome annotation databases

EnsemblFungiiSPAC24B11.12c.1; SPAC24B11.12c.1:pep; SPAC24B11.12c
GeneIDi2541560
KEGGispo:SPAC24B11.12c

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329670 Genomic DNA Translation: CAA91777.1
AB027875 Genomic DNA Translation: BAA87179.1
PIRiT38339 S62557
RefSeqiNP_592849.1, NM_001018250.2

3D structure databases

ProteinModelPortaliQ09891
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi278059, 29 interactors
STRINGi4896.SPAC24B11.12c.1

PTM databases

iPTMnetiQ09891

Proteomic databases

MaxQBiQ09891
PaxDbiQ09891
PRIDEiQ09891

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiSPAC24B11.12c.1; SPAC24B11.12c.1:pep; SPAC24B11.12c
GeneIDi2541560
KEGGispo:SPAC24B11.12c

Organism-specific databases

EuPathDBiFungiDB:SPAC24B11.12c
PomBaseiSPAC24B11.12c

Phylogenomic databases

HOGENOMiHOG000202528
InParanoidiQ09891
KOiK01530
OMAiPHRDLMN
OrthoDBiEOG092C0BQ4
PhylomeDBiQ09891

Enzyme and pathway databases

ReactomeiR-SPO-936837 Ion transport by P-type ATPases

Miscellaneous databases

PROiPR:Q09891

Family and domain databases

Gene3Di3.40.1110.10, 2 hits
3.40.50.1000, 2 hits
InterProiView protein in InterPro
IPR023299 ATPase_P-typ_cyto_dom_N
IPR018303 ATPase_P-typ_P_site
IPR023298 ATPase_P-typ_TM_dom_sf
IPR008250 ATPase_P-typ_transduc_dom_A_sf
IPR036412 HAD-like_sf
IPR023214 HAD_sf
IPR006539 P-type_ATPase_IV
IPR032631 P-type_ATPase_N
IPR001757 P_typ_ATPase
IPR032630 P_typ_ATPase_c
IPR026871 PLip_transp_ATPase
PANTHERiPTHR24092 PTHR24092, 1 hit
PTHR24092:SF34 PTHR24092:SF34, 1 hit
PfamiView protein in Pfam
PF16212 PhoLip_ATPase_C, 1 hit
PF16209 PhoLip_ATPase_N, 1 hit
SUPFAMiSSF56784 SSF56784, 2 hits
SSF81653 SSF81653, 2 hits
SSF81660 SSF81660, 2 hits
SSF81665 SSF81665, 3 hits
TIGRFAMsiTIGR01652 ATPase-Plipid, 1 hit
TIGR01494 ATPase_P-type, 2 hits
PROSITEiView protein in PROSITE
PS00154 ATPASE_E1_E2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiATCX_SCHPO
AccessioniPrimary (citable) accession number: Q09891
Secondary accession number(s): Q9USC3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: February 1, 1996
Last modified: July 18, 2018
This is version 143 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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