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Entry version 117 (25 May 2022)
Sequence version 1 (01 Feb 1996)
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Protein

Protein MON2 homolog

Gene

mon2

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Required for traffic between late Golgi and early endosomes. Required for endocytosis and maintenance of vacuolar structure (By similarity).

By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processProtein transport, Transport

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Protein MON2 homolog
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:mon2
ORF Names:SPAC23D3.13c
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri284812 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002485 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome I

Organism-specific databases

Schizosaccharomyces pombe database

More...
PomBasei
SPAC23D3.13c

Eukaryotic Pathogen, Vector and Host Database Resources

More...
VEuPathDBi
FungiDB:SPAC23D3.13c

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Golgi apparatus, Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001164191 – 1616Protein MON2 homologAdd BLAST1616

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei43Phosphoserine1 Publication1
Modified residuei660Phosphoserine1 Publication1

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQB - The MaxQuant DataBase

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MaxQBi
Q09853

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q09853

PRoteomics IDEntifications database

More...
PRIDEi
Q09853

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q09853

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Homodimer.

By similarity

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

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BioGRIDi
277988, 1 interactor

STRING: functional protein association networks

More...
STRINGi
4896.SPAC23D3.13c.1

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

AlphaFold Protein Structure Database

More...
AlphaFoldDBi
Q09853

SWISS-MODEL Repository - a database of annotated 3D protein structure models

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SMRi
Q09853

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the MON2 family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

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eggNOGi
KOG1848, Eukaryota

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_001169_1_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q09853

Identification of Orthologs from Complete Genome Data

More...
OMAi
DETIDCQ

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q09853

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR016024, ARM-type_fold
IPR032629, DCB_dom
IPR026829, Mon2-like
IPR032817, Mon2_C
IPR032691, Sec7_N

The PANTHER Classification System

More...
PANTHERi
PTHR10663:SF333, PTHR10663:SF333, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF16213, DCB, 1 hit
PF16206, Mon2_C, 1 hit
PF12783, Sec7_N, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48371, SSF48371, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q09853-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSLYDSLLSN LQSINVDTRK KNADLKKLAD GSLKFLYTNK NLSQDSLVSK
60 70 80 90 100
LKGNEAFYKP FLFCCAKKIE RHIYISLNSI QLLAINDALS PDILESLFNS
110 120 130 140 150
LNAVIQLGQD SQLRVLQIIP IICTHYAASM KLPILISLFR ICFNLHNSKN
160 170 180 190 200
SVVSNAAAAT LRQIVILVFD YLDYDTLAHK QEADLFLDSL SLFKGLCSLL
210 220 230 240 250
SAGKSESLNV DHISTTFGLE LLESILVNHH RLFQIPEFQD SVRKDLLPII
260 270 280 290 300
TASLASMSDF PVALRISRIL NIIFQHYVTS LTLDIEVIFS FIISSLDNSE
310 320 330 340 350
AAWKKALFLE VLRSIFSNTN LLYLMYTLFD GNEGRKPIIK KLVTSLSRIV
360 370 380 390 400
NEKPSVIGVG SRVVLADTFE DYSSTSSGNP PSSMEKVSGS FTGTKPEQII
410 420 430 440 450
GICRATILKT PCIEQFDKQE PPIIPFAYLV YLAMCSLASI SNGIADFVFQ
460 470 480 490 500
FYEDVGKKEF TLLIEGIKCE NFDSKEDSTA RPQNIIKCQY GLISENWTSF
510 520 530 540 550
LVAYSTFVSS ALAVELLKFC LNSYVNFVSV CTLFGLETPR DALLTTLSNK
560 570 580 590 600
AVPSNLLSGN MTHSASSSIS HNGRLSTSTM FSVEGLKEAA TTIAAIASYD
610 620 630 640 650
SNHDEKQKCF SLREILFLRC LSSIAKVVGE KMGKGWKILF ETFDKADIIL
660 670 680 690 700
NRSPTSKHLS TSSLNRVNSS NSNFQDSKSF STLMDYELVS YKNELSELMY
710 720 730 740 750
VTSSYSQPAY MEFLESLLAV ITSSSVHPIQ TLTAPRQSFN EDLLSANTKN
760 770 780 790 800
SVYKTSANRS ISGGIRLLRK SSEVFYSFSI LETVCSCNLD RFLDSKLDHS
810 820 830 840 850
GWSLISKSLS EVFKIINVAP ELRTRAANCL ANILVDVASR LSNENSPDSY
860 870 880 890 900
AFQEIFFESL GMLLPVTEVS DNTSRGVEYD ISTIGLEALV SILETVGHHV
910 920 930 940 950
LHGWQYVFEM LRFNCLNGAT CFGSEKGAKI VRLAFSCLQL ICTDFLASLD
960 970 980 990 1000
TSNYLDLMDT LLVFCRQLED ANVSLTAVGL FWNVSDTLKN MFSTSDFSCA
1010 1020 1030 1040 1050
YNSVEDLYAF TSMKSKEILP EVLWIMLLVH LADLCENSWA SVRNGAAQIL
1060 1070 1080 1090 1100
FRIFNSQCSK LGTNAWASCC QLVIMKLLHS QPIQNVSDVN NKKDEDDHEQ
1110 1120 1130 1140 1150
TSCLIISGIA DVFSENMSLL LNVNGILDVL EEAFQLMLRL HSDIYPKICI
1160 1170 1180 1190 1200
SNFKALRELS FSISEFGKEN ATFTLLIKLV FINWGRFCEV SFSERRLANI
1210 1220 1230 1240 1250
SQEGLTLLIE SVVFLLKAYN FGIEEIKDSL LQVRKAVFYE ESTSFALDVD
1260 1270 1280 1290 1300
FLSSLQLAVE SLTDLLISKF KLNHLVLELW SDVLTYAFNE EKTIRASLPT
1310 1320 1330 1340 1350
LICLSKKIFE NAENVVENHS LDFLNRGTMQ HMFESLLVPM RLKYRCPKAS
1360 1370 1380 1390 1400
RVNQSTLPIW VLASKCFVRL MINCFKDLKG SDAIEDAEKM QCLFLLTVEA
1410 1420 1430 1440 1450
TNSIISPNAD YEYVWSLEDV FENEDVSSLK QLHNLWKPHL QLNCLSDEVA
1460 1470 1480 1490 1500
QYYITLCKGS FYYQMRNTED MVISRSNLDI QKEAARNFFP STESPVSNRR
1510 1520 1530 1540 1550
QRIAVDCFSI LLDDYNSSYE HVSLTIRPIL QSRLCWSLKR YVADKSVSGY
1560 1570 1580 1590 1600
LPLSKSQEMD MSTVAECLNN HPSLYSNPIH YLLRKAYHTT NASPVATSLN
1610
AILGQLTLKN EVLNAI
Length:1,616
Mass (Da):181,451
Last modified:February 1, 1996 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iCB44B34EE2D568DA
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
CU329670 Genomic DNA Translation: CAA91248.1

Protein sequence database of the Protein Information Resource

More...
PIRi
T38288, S62504

NCBI Reference Sequences

More...
RefSeqi
NP_594550.1, NM_001019979.2

Genome annotation databases

Ensembl fungal genome annotation project

More...
EnsemblFungii
SPAC23D3.13c.1; SPAC23D3.13c.1:pep; SPAC23D3.13c

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
2541486

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
spo:SPAC23D3.13c

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329670 Genomic DNA Translation: CAA91248.1
PIRiT38288, S62504
RefSeqiNP_594550.1, NM_001019979.2

3D structure databases

AlphaFoldDBiQ09853
SMRiQ09853
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi277988, 1 interactor
STRINGi4896.SPAC23D3.13c.1

PTM databases

iPTMnetiQ09853

Proteomic databases

MaxQBiQ09853
PaxDbiQ09853
PRIDEiQ09853

Genome annotation databases

EnsemblFungiiSPAC23D3.13c.1; SPAC23D3.13c.1:pep; SPAC23D3.13c
GeneIDi2541486
KEGGispo:SPAC23D3.13c

Organism-specific databases

PomBaseiSPAC23D3.13c
VEuPathDBiFungiDB:SPAC23D3.13c

Phylogenomic databases

eggNOGiKOG1848, Eukaryota
HOGENOMiCLU_001169_1_0_1
InParanoidiQ09853
OMAiDETIDCQ
PhylomeDBiQ09853

Miscellaneous databases

Protein Ontology

More...
PROi
PR:Q09853

Family and domain databases

InterProiView protein in InterPro
IPR016024, ARM-type_fold
IPR032629, DCB_dom
IPR026829, Mon2-like
IPR032817, Mon2_C
IPR032691, Sec7_N
PANTHERiPTHR10663:SF333, PTHR10663:SF333, 1 hit
PfamiView protein in Pfam
PF16213, DCB, 1 hit
PF16206, Mon2_C, 1 hit
PF12783, Sec7_N, 1 hit
SUPFAMiSSF48371, SSF48371, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiMON2_SCHPO
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q09853
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: February 1, 1996
Last modified: May 25, 2022
This is version 117 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families
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