Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 135 (29 Sep 2021)
Sequence version 1 (01 Feb 1996)
Previous versions | rss
Add a publicationFeedback
Protein

Ascus wall endo-1,3(4)-beta-glucanase

Gene

eng2

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Promotes the release of ascospores from asci by hydrolyzing 1,3-beta-glucan in the ascus wall.

1 Publication

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionGlycosidase, Hydrolase

Protein family/group databases

Carbohydrate-Active enZymes

More...
CAZyi
GH81, Glycoside Hydrolase Family 81

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Ascus wall endo-1,3(4)-beta-glucanase1 Publication
Alternative name(s):
Endo-1,3(4)-beta-glucanase 2 (EC:3.2.1.61 Publication)
Short name:
Endo-1,3-beta-glucanase 2
Short name:
Endo-1,4-beta-glucanase 2
Laminarinase-2
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:eng2Imported
ORF Names:SPAC23D3.10cImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri284812 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002485 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome I

Organism-specific databases

Schizosaccharomyces pombe database

More...
PomBasei
SPAC23D3.10c, eng2

Eukaryotic Pathogen, Vector and Host Database Resources

More...
VEuPathDBi
FungiDB:SPAC23D3.10c

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei137 – 157HelicalSequence analysisAdd BLAST21
Transmembranei307 – 327HelicalSequence analysisAdd BLAST21
Transmembranei460 – 480HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the 'Pathology and Biotech' section describes the in vivo effects caused by ablation of the gene (or one or more transcripts) coding for the protein described in the entry. This includes gene knockout and knockdown, provided experiments have been performed in the context of a whole organism or a specific tissue, and not at the single-cell level.<p><a href='/help/disruption_phenotype' target='_top'>More...</a></p>Disruption phenotypei

Severely decreases occurrence of ascospore release from ascus during sporulation (PubMed:19542306). Decreases sporulation-specific endo-1,3-beta-glucanase activity (PubMed:19542306).1 Publication

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/manual/pathology_and_biotech_section">'Pathology and Biotech'</a> section describes the effect of the experimental mutation of one or more amino acid(s) on the biological properties of the protein.<p><a href='/help/mutagen' target='_top'>More...</a></p>Mutagenesisi537E → A: Severely decreases occurrence of ascospore release from ascus during sporulation. 1 Publication1

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002158181 – 706Ascus wall endo-1,3(4)-beta-glucanaseAdd BLAST706

Proteomic databases

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q09850

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q09850

PTM databases

SwissPalm database of S-palmitoylation events

More...
SwissPalmi
Q09850

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of the gene product at various stages of a cell, tissue or organism development. By default, the information is derived from experiments at the mRNA level, unless specified 'at the protein level'.<p><a href='/help/developmental_stage' target='_top'>More...</a></p>Developmental stagei

Present during vegetative growth at low level (at protein level) (PubMed:19542306). The level increases throughout meiosis and reaches its highest during sporulation (at protein level) (PubMed:19542306).1 Publication

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
277982, 11 interactors

STRING: functional protein association networks

More...
STRINGi
4896.SPAC23D3.10c.1

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q09850

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the glycosyl hydrolase 81 family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG2254, Eukaryota

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_005482_2_1_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q09850

Identification of Orthologs from Complete Genome Data

More...
OMAi
IHMIPIL

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q09850

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR005200, Endo-beta-glucanase
IPR040720, GH81_C
IPR040451, GH81_N

The PANTHER Classification System

More...
PANTHERi
PTHR31983, PTHR31983, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF17652, Glyco_hydro81C, 1 hit
PF03639, Glyco_hydro_81, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q09850-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDVLVPIYTG PINPVFPSRA HPSPPLGLTS NLFPIQTNKF YGNLYIGTRH
60 70 80 90 100
NPSWSHPYSV TWLNGSSYYG LAISHIDDSQ RVFGPDPESV PCQYYFNPAG
110 120 130 140 150
LYSIIISARE FASGNLLSLD QSRHFSIQAT LSATTSGSGT IILPIVAGMG
160 170 180 190 200
FVSGYYTNLT PVFNSSILFS SITKINFSRG YKYRIQLTDG KIWFLYAFPT
210 220 230 240 250
SSSSTFNLTL ASNSQLTTST KFTGLIQICK VPNESVNNSY PDTIYDASAG
260 270 280 290 300
VYTTSISLSA QVSGTTGEYW FRFATAGYTN LNPLMFALPH HMQSFGSDTQ
310 320 330 340 350
AYKTGLGLAS TTMGIMFAYA TKTWHLIEKN LPTQVGFLPI PWNGGSNTYS
360 370 380 390 400
PTALAAIRAA CATDINFDVV NASNLDSMYT SGKIVAMYAQ VCLVASRILG
410 420 430 440 450
DSTLTNTGLT KLKQAMARFT TNTQMYPLVY DTTYKGIIST AGYSSPLADY
460 470 480 490 500
GNTYYNDHHF HWGYHIYACA VIGLLDPSWL VNDNIRYVNA LLRDSANPSE
510 520 530 540 550
SDTYFAMFRN FDWFVGHSWA TGIFESGDGK DEESTSEDFN FLYATKLWGM
560 570 580 590 600
VRNDTVLINR ANLMLAVLKN SLNTYIYMTP TTSVQPSQIL GNYVTGITFM
610 620 630 640 650
NKVDYATYFS AEEYCKQGIH MIPTTPISGY LRSPSYVQQD WNAKIAPIIN
660 670 680 690 700
TFSNNWTGIL WSNYAIYDPK TAYNTFAAST FTADKIDNGA SKTWYLAMAA

GMGGSP
Length:706
Mass (Da):77,948
Last modified:February 1, 1996 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i7AA4A9BED26C37B6
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
CU329670 Genomic DNA Translation: CAA91245.1

Protein sequence database of the Protein Information Resource

More...
PIRi
S62501

NCBI Reference Sequences

More...
RefSeqi
NP_594547.1, NM_001019976.2

Genome annotation databases

Ensembl fungal genome annotation project

More...
EnsemblFungii
SPAC23D3.10c.1; SPAC23D3.10c.1:pep; SPAC23D3.10c

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
2541480

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
spo:SPAC23D3.10c

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329670 Genomic DNA Translation: CAA91245.1
PIRiS62501
RefSeqiNP_594547.1, NM_001019976.2

3D structure databases

SMRiQ09850
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi277982, 11 interactors
STRINGi4896.SPAC23D3.10c.1

Protein family/group databases

CAZyiGH81, Glycoside Hydrolase Family 81

PTM databases

SwissPalmiQ09850

Proteomic databases

MaxQBiQ09850
PaxDbiQ09850

Genome annotation databases

EnsemblFungiiSPAC23D3.10c.1; SPAC23D3.10c.1:pep; SPAC23D3.10c
GeneIDi2541480
KEGGispo:SPAC23D3.10c

Organism-specific databases

PomBaseiSPAC23D3.10c, eng2
VEuPathDBiFungiDB:SPAC23D3.10c

Phylogenomic databases

eggNOGiKOG2254, Eukaryota
HOGENOMiCLU_005482_2_1_1
InParanoidiQ09850
OMAiIHMIPIL
PhylomeDBiQ09850

Miscellaneous databases

Protein Ontology

More...
PROi
PR:Q09850

Family and domain databases

InterProiView protein in InterPro
IPR005200, Endo-beta-glucanase
IPR040720, GH81_C
IPR040451, GH81_N
PANTHERiPTHR31983, PTHR31983, 1 hit
PfamiView protein in Pfam
PF17652, Glyco_hydro81C, 1 hit
PF03639, Glyco_hydro_81, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiENG2_SCHPO
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q09850
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: February 1, 1996
Last modified: September 29, 2021
This is version 135 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  2. Glycosyl hydrolases
    Classification of glycosyl hydrolase families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again