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Entry version 172 (16 Oct 2019)
Sequence version 2 (13 Nov 2007)
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Protein

Neuroblast differentiation-associated protein AHNAK

Gene

AHNAK

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May be required for neuronal cell differentiation.

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Neuroblast differentiation-associated protein AHNAK
Alternative name(s):
Desmoyokin
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:AHNAK
Synonyms:PM227
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 11

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:347 AHNAK

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
103390 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q09666

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
79026

Open Targets

More...
OpenTargetsi
ENSG00000124942

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA24640

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q09666

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
AHNAK

Domain mapping of disease mutations (DMDM)

More...
DMDMi
160332335

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000645041 – 5890Neuroblast differentiation-associated protein AHNAKAdd BLAST5890

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei1N-acetylmethionineCombined sources1
Modified residuei41PhosphoserineCombined sources1
Modified residuei93PhosphoserineCombined sources1
Modified residuei101PhosphothreonineCombined sources1
Modified residuei115PhosphoserineCombined sources1
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section describes <strong>covalent linkages</strong> of various types formed <strong>between two proteins (interchain cross-links)</strong> or <strong>between two parts of the same protein (intrachain cross-links)</strong>, except the disulfide bonds that are annotated in the <a href="http://www.uniprot.org/manual/disulfid">'Disulfide bond'</a> subsection.<p><a href='/help/crosslnk' target='_top'>More...</a></p>Cross-linki134Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1); alternateCombined sources
Cross-linki134Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternateCombined sources
Modified residuei135PhosphoserineCombined sources1
Modified residuei158PhosphothreonineCombined sources1
Modified residuei177PhosphoserineCombined sources1
Cross-linki181Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Modified residuei210PhosphoserineCombined sources1
Modified residuei212PhosphoserineCombined sources1
Modified residuei216PhosphoserineCombined sources1
Modified residuei218PhosphothreonineCombined sources1
Modified residuei220PhosphoserineCombined sources1
Modified residuei256PhosphoserineCombined sources1
Modified residuei270Omega-N-methylarginineCombined sources1
Modified residuei332PhosphoserineCombined sources1
Modified residuei337PhosphoserineCombined sources1
Modified residuei379PhosphoserineCombined sources1
Modified residuei470PhosphoserineCombined sources1
Modified residuei490PhosphothreonineCombined sources1
Modified residuei511PhosphoserineCombined sources1
Modified residuei551PhosphothreonineCombined sources1
Modified residuei553PhosphothreonineCombined sources1
Modified residuei559PhosphoserineCombined sources1
Modified residuei570PhosphoserineCombined sources1
Modified residuei572PhosphoserineCombined sources1
Modified residuei658PhosphoserineCombined sources1
Cross-linki712Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Cross-linki763Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Modified residuei793PhosphoserineCombined sources1
Modified residuei819PhosphoserineCombined sources1
Cross-linki891Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Cross-linki942Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1)Combined sources
Cross-linki961Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1); alternateCombined sources
Cross-linki961Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternateCombined sources
Modified residuei1010PhosphoserineCombined sources1
Modified residuei1042PhosphoserineCombined sources1
Modified residuei1068PhosphoserineCombined sources1
Modified residuei1170PhosphoserineCombined sources1
Modified residuei1192PhosphothreonineCombined sources1
Modified residuei1196PhosphoserineCombined sources1
Modified residuei1208N6-methyllysineCombined sources1
Modified residuei1286PhosphoserineCombined sources1
Modified residuei1298PhosphoserineCombined sources1
Modified residuei1580PhosphoserineCombined sources1
Modified residuei1654PhosphoserineCombined sources1
Modified residuei1666N6-methyllysineCombined sources1
Cross-linki1726Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Modified residuei1856PhosphoserineCombined sources1
Modified residuei1868N6-methyllysineCombined sources1
Modified residuei1923PhosphoserineCombined sources1
Modified residuei1935N6-methyllysineCombined sources1
Modified residuei1986PhosphothreonineCombined sources1
Modified residuei1990PhosphoserineCombined sources1
Modified residuei2002N6-methyllysineCombined sources1
Cross-linki2062Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Modified residuei2092PhosphoserineCombined sources1
Modified residuei2118PhosphoserineCombined sources1
Modified residuei2130N6-methyllysineCombined sources1
Cross-linki2132Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1)Combined sources
Modified residuei2138PhosphoserineCombined sources1
Modified residuei2181PhosphothreonineCombined sources1
Modified residuei2287PhosphoserineCombined sources1
Modified residuei2309PhosphothreonineCombined sources1
Modified residuei2397PhosphoserineCombined sources1
Cross-linki2524Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Cross-linki2575Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1)Combined sources
Modified residuei2580PhosphoserineCombined sources1
Cross-linki2594Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1)Combined sources
Modified residuei2600PhosphoserineCombined sources1
Modified residuei2670PhosphoserineCombined sources1
Cross-linki2703Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1)Combined sources
Modified residuei2708PhosphoserineCombined sources1
Cross-linki2722Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1)Combined sources
Modified residuei2728PhosphoserineCombined sources1
Modified residuei2798PhosphoserineCombined sources1
Modified residuei2832PhosphothreonineCombined sources1
Modified residuei2845PhosphothreonineCombined sources1
Cross-linki2908Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Cross-linki2959Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1)Combined sources
Modified residuei3054PhosphoserineCombined sources1
Cross-linki3087Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1)Combined sources
Modified residuei3092PhosphoserineCombined sources1
Modified residuei3182PhosphoserineCombined sources1
Cross-linki3215Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1)Combined sources
Modified residuei3220PhosphoserineCombined sources1
Modified residuei3362PhosphoserineCombined sources1
Modified residuei3409PhosphoserineCombined sources1
Modified residuei3412PhosphoserineCombined sources1
Modified residuei3426PhosphoserineCombined sources1
Modified residuei3544PhosphoserineCombined sources1
Cross-linki3667Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1)Combined sources
Modified residuei3716PhosphothreonineCombined sources1
Modified residuei3746PhosphoserineCombined sources1
Cross-linki3760Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1)Combined sources
Modified residuei3766PhosphoserineCombined sources1
Modified residuei3836PhosphoserineCombined sources1
Cross-linki3869Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1)Combined sources
Modified residuei3874PhosphoserineCombined sources1
Modified residuei3964PhosphoserineCombined sources1
Cross-linki3997Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1)Combined sources
Modified residuei4002PhosphoserineCombined sources1
Cross-linki4016Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1)Combined sources
Modified residuei4022PhosphoserineCombined sources1
Modified residuei4092PhosphoserineCombined sources1
Modified residuei4100PhosphothreonineCombined sources1
Modified residuei4150PhosphoserineCombined sources1
Modified residuei4220PhosphoserineCombined sources1
Cross-linki4253Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1)Combined sources
Modified residuei4258PhosphoserineCombined sources1
Cross-linki4272Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1)Combined sources
Modified residuei4278PhosphoserineCombined sources1
Modified residuei4360PhosphoserineCombined sources1
Cross-linki4381Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1)Combined sources
Cross-linki4400Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1)Combined sources
Modified residuei4406PhosphoserineCombined sources1
Modified residuei4425PhosphoserineCombined sources1
Modified residuei4430PhosphothreonineCombined sources1
Cross-linki4455Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1)Combined sources
Modified residuei4460PhosphoserineCombined sources1
Cross-linki4474Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1)Combined sources
Modified residuei4480PhosphoserineCombined sources1
Modified residuei4486PhosphoserineCombined sources1
Modified residuei4516PhosphoserineCombined sources1
Modified residuei4520PhosphoserineCombined sources1
Modified residuei4564PhosphothreonineCombined sources1
Modified residuei4684PhosphoserineCombined sources1
Modified residuei4722PhosphoserineCombined sources1
Modified residuei4766PhosphothreonineCombined sources1
Modified residuei4812PhosphoserineCombined sources1
Modified residuei4900PhosphoserineCombined sources1
Modified residuei4903PhosphoserineCombined sources1
Modified residuei4908PhosphoserineCombined sources1
Modified residuei4953PhosphoserineCombined sources1
Modified residuei4960PhosphoserineCombined sources1
Modified residuei4986PhosphoserineCombined sources1
Modified residuei4993PhosphoserineCombined sources1
Modified residuei5009PhosphothreonineCombined sources1
Modified residuei5077PhosphoserineCombined sources1
Modified residuei5099PhosphoserineCombined sources1
Modified residuei5110PhosphoserineCombined sources1
Modified residuei5125PhosphoserineCombined sources1
Modified residuei5261PhosphoserineCombined sources1
Modified residuei5318PhosphoserineCombined sources1
Modified residuei5332PhosphoserineCombined sources1
Modified residuei5369PhosphoserineCombined sources1
Modified residuei5386PhosphoserineCombined sources1
Modified residuei5393PhosphoserineCombined sources1
Modified residuei5400PhosphoserineCombined sources1
Modified residuei5415PhosphothreonineCombined sources1
Modified residuei5448PhosphoserineCombined sources1
Modified residuei5519PhosphoserineCombined sources1
Modified residuei5530PhosphoserineCombined sources1
Modified residuei5552PhosphoserineCombined sources1
Modified residuei5577PhosphoserineCombined sources1
Modified residuei5620PhosphoserineCombined sources1
Cross-linki5623Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Modified residuei5641PhosphoserineCombined sources1
Modified residuei5731PhosphoserineCombined sources1
Modified residuei5739PhosphoserineCombined sources1
Modified residuei5749PhosphoserineCombined sources1
Modified residuei5752PhosphoserineCombined sources1
Modified residuei5762PhosphoserineCombined sources1
Modified residuei5763PhosphoserineCombined sources1
Modified residuei5780PhosphoserineCombined sources1
Modified residuei5782PhosphoserineCombined sources1
Modified residuei5790PhosphoserineCombined sources1
Modified residuei5793PhosphoserineCombined sources1
Modified residuei5794PhosphothreonineCombined sources1
Modified residuei5824PhosphothreonineCombined sources1
Modified residuei5830PhosphoserineCombined sources1
Modified residuei5841PhosphoserineCombined sources1
Modified residuei5845PhosphothreonineCombined sources1
Modified residuei5851PhosphoserineCombined sources1
Modified residuei5857PhosphoserineCombined sources1
Modified residuei5863PhosphoserineCombined sources1

Keywords - PTMi

Acetylation, Isopeptide bond, Methylation, Phosphoprotein, Ubl conjugation

Proteomic databases

The CPTAC Assay portal

More...
CPTACi
CPTAC-457
CPTAC-458
CPTAC-958

Encyclopedia of Proteome Dynamics

More...
EPDi
Q09666

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q09666

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q09666

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q09666

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q09666

PeptideAtlas

More...
PeptideAtlasi
Q09666

PRoteomics IDEntifications database

More...
PRIDEi
Q09666

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
107
58724 [Q09666-1]

PTM databases

CarbonylDB database of protein carbonylation sites

More...
CarbonylDBi
Q09666

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q09666

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q09666

SwissPalm database of S-palmitoylation events

More...
SwissPalmi
Q09666

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000124942 Expressed in 244 organ(s), highest expression level in olfactory bulb

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q09666 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q09666 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA019010
HPA019070
HPA026643

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with DYSF; the interaction is direct and Ca2+-independent.

1 Publication

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
122494, 137 interactors

ComplexPortal: manually curated resource of macromolecular complexes

More...
ComplexPortali
CPX-850 AHNAK - Annexin A2 - S100-A10 complex

CORUM comprehensive resource of mammalian protein complexes

More...
CORUMi
Q09666

Protein interaction database and analysis system

More...
IntActi
Q09666, 102 interactors

Molecular INTeraction database

More...
MINTi
Q09666

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000367263

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q09666

Database of comparative protein structure models

More...
ModBasei
Search...

Protein Data Bank in Europe - Knowledge Base

More...
PDBe-KBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini9 – 90PDZPROSITE-ProRule annotationAdd BLAST82

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a short (usually not more than 20 amino acids) conserved sequence motif of biological significance.<p><a href='/help/motif' target='_top'>More...</a></p>Motifi4971 – 4979Nuclear localization signalSequence analysis9
Motifi5019 – 5027Nuclear localization signalSequence analysis9
Motifi5034 – 5039Nuclear localization signalSequence analysis6
Motifi5706 – 5716Nuclear localization signalSequence analysisAdd BLAST11
Motifi5772 – 5779Nuclear localization signalSequence analysis8

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi5458 – 5654Gly-richAdd BLAST197

Keywords - Domaini

Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410JR2V Eukaryota
ENOG410ZVP4 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000154902

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000033865

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q09666

Identification of Orthologs from Complete Genome Data

More...
OMAi
INAPHGK

Database of Orthologous Groups

More...
OrthoDBi
71329at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q09666

TreeFam database of animal gene trees

More...
TreeFami
TF350595

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001478 PDZ
IPR036034 PDZ_sf

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00228 PDZ, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF50156 SSF50156, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50106 PDZ, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 5 potential isoforms that are computationally mapped.Show allAlign All