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Protein

Putative cytochrome P450 CYP13A10

Gene

cyp-13A10

Organism
Caenorhabditis elegans
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Cytochromes P450 are a group of heme-thiolate monooxygenases. They oxidize a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.

Cofactori

hemeBy similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi465Iron (heme axial ligand)By similarity1

GO - Molecular functioni

Keywordsi

Molecular functionMonooxygenase, Oxidoreductase
LigandHeme, Iron, Metal-binding

Enzyme and pathway databases

ReactomeiR-CEL-211958 Miscellaneous substrates
R-CEL-211979 Eicosanoids
R-CEL-211981 Xenobiotics
R-CEL-2162123 Synthesis of Prostaglandins (PG) and Thromboxanes (TX)
R-CEL-5423646 Aflatoxin activation and detoxification
R-CEL-9027307 Biosynthesis of maresin-like SPMs

Names & Taxonomyi

Protein namesi
Recommended name:
Putative cytochrome P450 CYP13A10 (EC:1.14.-.-)
Gene namesi
Name:cyp-13A10
Synonyms:cyp13a10
ORF Names:ZK1320.4
OrganismiCaenorhabditis elegans
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome II

Organism-specific databases

WormBaseiZK1320.4 ; CE37736 ; WBGene00014254 ; cyp-13A10

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei3 – 23HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000522691 – 519Putative cytochrome P450 CYP13A10Add BLAST519

Proteomic databases

PaxDbiQ09653
PRIDEiQ09653

Expressioni

Gene expression databases

BgeeiWBGene00014254

Interactioni

Protein-protein interaction databases

STRINGi6239.ZK1320.4

Structurei

3D structure databases

ProteinModelPortaliQ09653
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the cytochrome P450 family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG0158 Eukaryota
COG2124 LUCA
GeneTreeiENSGT00900000140779
HOGENOMiHOG000016177
InParanoidiQ09653
KOiK17861
OMAiGDFMDSM
OrthoDBiEOG091G0JNC
PhylomeDBiQ09653

Family and domain databases

Gene3Di1.10.630.10, 1 hit
InterProiView protein in InterPro
IPR001128 Cyt_P450
IPR017972 Cyt_P450_CS
IPR002401 Cyt_P450_E_grp-I
IPR036396 Cyt_P450_sf
PfamiView protein in Pfam
PF00067 p450, 1 hit
PRINTSiPR00463 EP450I
PR00385 P450
SUPFAMiSSF48264 SSF48264, 1 hit
PROSITEiView protein in PROSITE
PS00086 CYTOCHROME_P450, 1 hit

Sequencei

Sequence statusi: Complete.

Q09653-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSVILLAIPT LFIGFISYYL WIWTYWRRRG IPGPLGYPLV GSFPKTLKSE
60 70 80 90 100
YPQYLQIRDW TKLYGPIYGY TEGTIKTLIV SDIDIVRQIF VEQYDNFYGR
110 120 130 140 150
KLNPIQGDPE KDERTNLFSA QGFRWKRLRA ISSPTFSNNS LRKINVTVED
160 170 180 190 200
SAMELLRHIE EQTSEGQQID MLQFYQEFTM DTIGRIAMGQ TDSQMFKNPL
210 220 230 240 250
LKFVRAIFGD NRKHIPLIGG VFPTLAQVFR FFMLKFPLLG AANFIHVNKT
260 270 280 290 300
VVTAVQNRID QRENDRKNGI EIGEPQDFID LFLEARADDV EHFQENNGDF
310 320 330 340 350
SKTSSYGNRQ LTTQEIVGQC LVFLIAGFDT TALSLSYTTF LLATHPEVQK
360 370 380 390 400
KLQEEIEREC IEPSISFDHL SKLKYMDCII KETLRLYPLG TMANSRRCMR
410 420 430 440 450
ATKLGNVEVE VGTMVQVDTW SLHTDTKIWG DDAKEFKPER WLDPNCDQVF
460 470 480 490 500
QKGGYISFGL GPRQCVGMRL AYMEEKMLLA HILRKYTFEV GTKTEIPLKL
510
VGRATTQPET VWMHLKQRI
Length:519
Mass (Da):60,017
Last modified:May 10, 2005 - v3
Checksum:iAFC961B7E214B12A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z46934 Genomic DNA Translation: CAA87042.3
PIRiT27750
RefSeqiNP_496085.3, NM_063684.4
UniGeneiCel.7908

Genome annotation databases

EnsemblMetazoaiZK1320.4; ZK1320.4; WBGene00014254
GeneIDi174522
KEGGicel:CELE_ZK1320.4
UCSCiZK1320.4 c. elegans

Similar proteinsi

Entry informationi

Entry nameiC13AA_CAEEL
AccessioniPrimary (citable) accession number: Q09653
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: May 10, 2005
Last modified: May 23, 2018
This is version 125 of the entry and version 3 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Caenorhabditis elegans
    Caenorhabditis elegans: entries, gene names and cross-references to WormBase
  2. SIMILARITY comments
    Index of protein domains and families

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