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UniProtKB - Q09641 (Q09641_CAEEL)
Protein
alpha-1,2-Mannosidase
Gene
CELE_ZC506.1
Organism
Caenorhabditis elegans
Status
Functioni
GO - Molecular functioni
- calcium ion binding Source: InterPro
- mannosyl-oligosaccharide 1,2-alpha-mannosidase activity Source: InterPro
GO - Biological processi
- carbohydrate metabolic process Source: InterPro
- endoplasmic reticulum mannose trimming Source: InterPro
- mannose trimming involved in glycoprotein ERAD pathway Source: InterPro
Keywordsi
Molecular function | GlycosidaseUniRule annotation, Hydrolase |
Protein family/group databases
CAZyi | GH47, Glycoside Hydrolase Family 47 |
Names & Taxonomyi
Protein namesi | |
Gene namesi | ORF Names:CELE_ZC506.1Imported, ZC506.1Imported |
Organismi | Caenorhabditis elegansImported |
Taxonomic identifieri | 6239 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Ecdysozoa › Nematoda › Chromadorea › Rhabditida › Rhabditina › Rhabditomorpha › Rhabditoidea › Rhabditidae › Peloderinae › Caenorhabditis |
Proteomesi |
|
Organism-specific databases
WormBasei | ZC506.1 ; CE37461 ; WBGene00013919 |
Subcellular locationi
Endoplasmic reticulum
Other locations
- membrane Source: InterPro
Keywords - Cellular componenti
Endoplasmic reticulumARBA annotationPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Signal peptidei | 1 – 21 | Sequence analysisAdd BLAST | 21 | |
ChainiPRO_5004167190 | 22 – 931 | alpha-1,2-MannosidaseSequence analysisAdd BLAST | 910 |
Keywords - PTMi
GlycoproteinARBA annotationProteomic databases
EPDi | Q09641 |
PaxDbi | Q09641 |
PeptideAtlasi | Q09641 |
Expressioni
Gene expression databases
Bgeei | WBGene00013919, Expressed in multi-cellular organism and 5 other tissues |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 675 – 760 | PAInterPro annotationAdd BLAST | 86 |
Sequence similaritiesi
Keywords - Domaini
SignalSequence analysisPhylogenomic databases
eggNOGi | KOG2430, Eukaryota |
GeneTreei | ENSGT00940000168818 |
HOGENOMi | CLU_003818_4_1_1 |
InParanoidi | Q09641 |
OMAi | RRWDRRE |
OrthoDBi | 434316at2759 |
PhylomeDBi | Q09641 |
Family and domain databases
CDDi | cd02126, PA_EDEM3_like, 1 hit |
Gene3Di | 1.50.10.10, 1 hit |
InterProi | View protein in InterPro IPR012341, 6hp_glycosidase-like_sf IPR044674, EDEM1/2/3 IPR037322, EDEM3_PA IPR001382, Glyco_hydro_47 IPR003137, PA_domain IPR036026, Seven-hairpin_glycosidases |
PANTHERi | PTHR45679, PTHR45679, 1 hit |
Pfami | View protein in Pfam PF01532, Glyco_hydro_47, 1 hit PF02225, PA, 1 hit |
PRINTSi | PR00747, GLYHDRLASE47 |
SUPFAMi | SSF48225, SSF48225, 1 hit |
i Sequence
Sequence statusi: Complete.
Q09641-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MFNTRWKVFI FLALCYRISH GEELDKKKLQ KEAYDMFMHG YNSYMNYAFP
60 70 80 90 100
ADELMPLSCK GRIRGVTPSR GDVDDVLGNF SVTLLDSLDT LVVMNELDEF
110 120 130 140 150
EKAIDLVIKH VRFDSDHVVS VFETNIRVLG GLISAHVLAE LVKEKYPNRL
160 170 180 190 200
TTYDNQLLKM ATEVGNRLLP AFNTTSGLPF SRINLKHGMQ DHLKRQKDTC
210 220 230 240 250
TACGGTMILE FAALTSLTGD PIYEKKARKA MDFLWQQRHR SSDLMGTVLN
260 270 280 290 300
VHSGDWTRRE SGIGAGIDSY YEYTLKAYIL LGDESYLDRF NKHYEAIKRY
310 320 330 340 350
INKGPIFVDV HMHRPTVATR GFMDSLLAFW PGLQVLKGDV KEAIEMHEML
360 370 380 390 400
FQVIQKHKFL PEAFTHDFQV HWAEHPIRPE FVESTYFLYR ATKDPHYLHV
410 420 430 440 450
AKQIMDSINK YVKVPCGFAA LKDIRTMVKE DQMESFVLSE TFKYLYMIFT
460 470 480 490 500
DPEDLMFDPD HYVLTTEAHF LPLSIGHKEK IENKINPRRM ILRADEPQQK
510 520 530 540 550
NYVCANPIDF TKLPTEREEA QLIRERTKIM LGELRNGASA GGAAPGNMIC
560 570 580 590 600
ESPADRIRAW AFSSSNQEHV KQLVMMGIEL ITLSDGRLHL SHKSVNAASP
610 620 630 640 650
LYARWGMEFM EEMQHYVEQL DKSGGTPEHT QQFVQILNRP YYGKPYLRGS
660 670 680 690 700
AAQFGRDIAA TKALVGRAAK TIPFRACDKI LNADQVVGKI AVVERSDCVF
710 720 730 740 750
QDKARFVQQA GAIGMVVIDH ESNSQYVGDR PTFSMAVDKD GKDDIGIPSI
760 770 780 790 800
FLFRAEGDHL LRSLKMHSET VISISSHHLS IENTIGRLLR YGKMFKFPEY
810 820 830 840 850
PQCSLRDGDI ILHNLDYPEV ILNLRFNGIN QDSDPRLHQE IVERHVTELQ
860 870 880 890 900
KYLEFKDADY AFQFYEFFRT AAYGALDLNV ENSKLLTVIS ALSTLKTKPI
910 920 930
PPSVFARLPG EITKVRCIPR GEEMPCVRLS T
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BX284606 Genomic DNA Translation: CAA87371.3 |
PIRi | T27625 |
RefSeqi | NP_509671.3, NM_077270.5 |
Genome annotation databases
EnsemblMetazoai | ZC506.1.1; ZC506.1.1; WBGene00013919 ZC506.1.2; ZC506.1.2; WBGene00013919 |
GeneIDi | 181210 |
KEGGi | cel:CELE_ZC506.1 |
UCSCi | ZC506.1, c. elegans |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BX284606 Genomic DNA Translation: CAA87371.3 |
PIRi | T27625 |
RefSeqi | NP_509671.3, NM_077270.5 |
3D structure databases
SMRi | Q09641 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 6239.ZC506.1 |
Protein family/group databases
CAZyi | GH47, Glycoside Hydrolase Family 47 |
Proteomic databases
EPDi | Q09641 |
PaxDbi | Q09641 |
PeptideAtlasi | Q09641 |
Genome annotation databases
EnsemblMetazoai | ZC506.1.1; ZC506.1.1; WBGene00013919 ZC506.1.2; ZC506.1.2; WBGene00013919 |
GeneIDi | 181210 |
KEGGi | cel:CELE_ZC506.1 |
UCSCi | ZC506.1, c. elegans |
Organism-specific databases
CTDi | 181210 |
WormBasei | ZC506.1 ; CE37461 ; WBGene00013919 |
Phylogenomic databases
eggNOGi | KOG2430, Eukaryota |
GeneTreei | ENSGT00940000168818 |
HOGENOMi | CLU_003818_4_1_1 |
InParanoidi | Q09641 |
OMAi | RRWDRRE |
OrthoDBi | 434316at2759 |
PhylomeDBi | Q09641 |
Gene expression databases
Bgeei | WBGene00013919, Expressed in multi-cellular organism and 5 other tissues |
Family and domain databases
CDDi | cd02126, PA_EDEM3_like, 1 hit |
Gene3Di | 1.50.10.10, 1 hit |
InterProi | View protein in InterPro IPR012341, 6hp_glycosidase-like_sf IPR044674, EDEM1/2/3 IPR037322, EDEM3_PA IPR001382, Glyco_hydro_47 IPR003137, PA_domain IPR036026, Seven-hairpin_glycosidases |
PANTHERi | PTHR45679, PTHR45679, 1 hit |
Pfami | View protein in Pfam PF01532, Glyco_hydro_47, 1 hit PF02225, PA, 1 hit |
PRINTSi | PR00747, GLYHDRLASE47 |
SUPFAMi | SSF48225, SSF48225, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | Q09641_CAEEL | |
Accessioni | Q09641Primary (citable) accession number: Q09641 Secondary accession number(s): Q09642 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | November 1, 1996 |
Last sequence update: | November 23, 2004 | |
Last modified: | January 19, 2022 | |
This is version 143 of the entry and version 3 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |