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Entry version 144 (07 Apr 2021)
Sequence version 1 (01 Nov 1996)
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Protein
Submitted name:

ACB domain-containing protein

Gene

ech-4

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-CEL-390247, Beta-oxidation of very long chain fatty acids
R-CEL-9033241, Peroxisomal protein import

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
ACB domain-containing proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ech-4Imported
ORF Names:CELE_R06F6.9Imported, R06F6.9Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiCaenorhabditis elegansImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri6239 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditinaRhabditomorphaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001940 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome II

Organism-specific databases

WormBase

More...
WormBasei
R06F6.9 ; CE01625 ; WBGene00001153 ; ech-4

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q09603

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q09603

PeptideAtlas

More...
PeptideAtlasi
Q09603

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
WBGene00001153, Expressed in material anatomical entity and 5 other tissues

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
6239.R06F6.9

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

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SMRi
Q09603

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini25 – 110ACBInterPro annotationAdd BLAST86

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili22 – 42Sequence analysisAdd BLAST21

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0016, Eukaryota
KOG0817, Eukaryota

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_009834_7_2_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q09603

Identification of Orthologs from Complete Genome Data

More...
OMAi
LGYHRAA

Database of Orthologous Groups

More...
OrthoDBi
1471901at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q09603

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00435, ACBP, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.12.10, 1 hit
1.20.80.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR000582, Acyl-CoA-binding_protein
IPR035984, Acyl-CoA-binding_sf
IPR029045, ClpP/crotonase-like_dom_sf
IPR001753, Enoyl-CoA_hydra/iso
IPR014748, Enoyl-CoA_hydra_C
IPR014352, FERM/acyl-CoA-bd_prot_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00887, ACBP, 1 hit
PF00378, ECH_1, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00689, ACOABINDINGP

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF47027, SSF47027, 1 hit
SSF52096, SSF52096, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51228, ACB_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q09603-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MLRNLTLAAR SVLYNPQVSV RSFSAQADFE KAQKNLKTLK EEPDNDVKLQ
60 70 80 90 100
LYGLFKQATA GDVQGKRPGM MDFVGRAKYD AWNTLKGQTQ DEARANYAKL
110 120 130 140 150
VGGLISEEAS AAPEPTGPSI EGLENVDGLS VTREGKVFKI ALNRPKKFNA
160 170 180 190 200
LTLEMYQGIQ KALEVSNNDK STSITVITAN GSYYCAGNDL TNFKAAAGGT
210 220 230 240 250
KEQIADMANT AKVIMKDYVN AYINHEKPLI ALINGPAVGI AVTVLGMFDY
260 270 280 290 300
VIATDKASFH TPFAPLGQSP EGVSSYTFPL IMGSLRASEM LLVCKKISAQ
310 320 330 340 350
TAKDYGLVNE VVPDAEFQSH AQKTVEAFSQ LPPETLRINK KLLRSLHKEK
360 370 380
LLEVNNIEAD QICERWQSKE CHQAIAAFMT KGAKK
Length:385
Mass (Da):42,104
Last modified:November 1, 1996 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iF89BDA8A80547398
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
BX284602 Genomic DNA Translation: CAA86779.1

Protein sequence database of the Protein Information Resource

More...
PIRi
T23980

NCBI Reference Sequences

More...
RefSeqi
NP_496330.1, NM_063929.6

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
R06F6.9.1; R06F6.9.1; WBGene00001153
R06F6.9.2; R06F6.9.2; WBGene00001153

UCSC genome browser

More...
UCSCi
R06F6.9, c. elegans

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284602 Genomic DNA Translation: CAA86779.1
PIRiT23980
RefSeqiNP_496330.1, NM_063929.6

3D structure databases

SMRiQ09603
ModBaseiSearch...

Protein-protein interaction databases

STRINGi6239.R06F6.9

Proteomic databases

EPDiQ09603
PaxDbiQ09603
PeptideAtlasiQ09603

Genome annotation databases

EnsemblMetazoaiR06F6.9.1; R06F6.9.1; WBGene00001153
R06F6.9.2; R06F6.9.2; WBGene00001153
UCSCiR06F6.9, c. elegans

Organism-specific databases

WormBaseiR06F6.9 ; CE01625 ; WBGene00001153 ; ech-4

Phylogenomic databases

eggNOGiKOG0016, Eukaryota
KOG0817, Eukaryota
HOGENOMiCLU_009834_7_2_1
InParanoidiQ09603
OMAiLGYHRAA
OrthoDBi1471901at2759
PhylomeDBiQ09603

Enzyme and pathway databases

ReactomeiR-CEL-390247, Beta-oxidation of very long chain fatty acids
R-CEL-9033241, Peroxisomal protein import

Gene expression databases

BgeeiWBGene00001153, Expressed in material anatomical entity and 5 other tissues

Family and domain databases

CDDicd00435, ACBP, 1 hit
Gene3Di1.10.12.10, 1 hit
1.20.80.10, 1 hit
InterProiView protein in InterPro
IPR000582, Acyl-CoA-binding_protein
IPR035984, Acyl-CoA-binding_sf
IPR029045, ClpP/crotonase-like_dom_sf
IPR001753, Enoyl-CoA_hydra/iso
IPR014748, Enoyl-CoA_hydra_C
IPR014352, FERM/acyl-CoA-bd_prot_sf
PfamiView protein in Pfam
PF00887, ACBP, 1 hit
PF00378, ECH_1, 1 hit
PRINTSiPR00689, ACOABINDINGP
SUPFAMiSSF47027, SSF47027, 1 hit
SSF52096, SSF52096, 1 hit
PROSITEiView protein in PROSITE
PS51228, ACB_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ09603_CAEEL
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q09603
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: April 7, 2021
This is version 144 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Proteomics identificationCombined sources, Reference proteomeImported
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