We will be switching to the new UniProt website on Tuesday, June 28. Please explore and share your feedback.
Take me to UniProt BETA
UniProtKB - Q09578 (COL75_CAEEL)
Protein
Putative cuticle collagen 75
Gene
col-75
Organism
Caenorhabditis elegans
Status
Functioni
Nematode cuticles are composed largely of collagen-like proteins. The cuticle functions both as an exoskeleton and as a barrier to protect the worm from its environment (By similarity).
By similarityGO - Molecular functioni
- structural constituent of cuticle Source: UniProtKB-KW
Names & Taxonomyi
Protein namesi | Recommended name: Putative cuticle collagen 75 |
Gene namesi | Name:col-75 ORF Names:K03H9.2 |
Organismi | Caenorhabditis elegans |
Taxonomic identifieri | 6239 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Ecdysozoa › Nematoda › Chromadorea › Rhabditida › Rhabditina › Rhabditomorpha › Rhabditoidea › Rhabditidae › Peloderinae › Caenorhabditis |
Proteomesi |
|
Organism-specific databases
WormBasei | K03H9.2 ; CE01996 ; WBGene00000651 ; col-75 |
Subcellular locationi
Other locations
- collagen trimer Source: UniProtKB-KW
Keywords - Cellular componenti
CuticlePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000127605 | 1 – 285 | Putative cuticle collagen 75Add BLAST | 285 |
Keywords - PTMi
Disulfide bondProteomic databases
PaxDbi | Q09578 |
Expressioni
Gene expression databases
Bgeei | WBGene00000651, Expressed in pharyngeal muscle cell (C elegans) and 4 other tissues |
Interactioni
Subunit structurei
Collagen polypeptide chains are complexed within the cuticle by disulfide bonds and other types of covalent cross-links.
By similarityProtein-protein interaction databases
STRINGi | 6239.K03H9.2 |
Family & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 87 – 116 | Triple-helical regionAdd BLAST | 30 | |
Regioni | 133 – 261 | Triple-helical regionAdd BLAST | 129 | |
Regioni | 207 – 257 | DisorderedSequence analysisAdd BLAST | 51 |
Sequence similaritiesi
Belongs to the cuticular collagen family.Curated
Keywords - Domaini
Collagen, RepeatPhylogenomic databases
eggNOGi | KOG3544, Eukaryota |
GeneTreei | ENSGT00940000164076 |
HOGENOMi | CLU_001074_4_3_1 |
InParanoidi | Q09578 |
OMAi | RRQKRHW |
OrthoDBi | 1567071at2759 |
PhylomeDBi | Q09578 |
Family and domain databases
InterProi | View protein in InterPro IPR002486, Col_cuticle_N IPR008160, Collagen |
Pfami | View protein in Pfam PF01484, Col_cuticle_N, 1 hit PF01391, Collagen, 3 hits |
i Sequence
Sequence statusi: Complete.
Q09578-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MRASPLLSLS IFITFVSIFS LLTYLPSFFA QISRIERQLE EELDEFLNIE
60 70 80 90 100
HEFRKEFDIY PKNYERRQKK HVYSYCECEY INTCPPGRIG ITGPDGQPGK
110 120 130 140 150
DGLPGMPGSP GIPGELPNIL YQQVFGCRIC PYGPKGKSGY KGIDGPPGIP
160 170 180 190 200
GWPGEPGVRG MNGERGSTGL DGAPGEPGSP GLPGFAGLPG SIGITGIKGV
210 220 230 240 250
MGEVGEPGAP GIPGEEGLSG PTGQPGSPGS IGAMGYEGAY GDRGEPGPPG
260 270 280
PIGRRGGPGL DSHYCPCPSR KMFLSILREK TKKQL
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | FO081582 Genomic DNA Translation: CCD72607.1 |
PIRi | S60598 |
RefSeqi | NP_495294.1, NM_062893.1 |
Genome annotation databases
EnsemblMetazoai | K03H9.2.1; K03H9.2.1; WBGene00000651 |
GeneIDi | 186968 |
KEGGi | cel:CELE_K03H9.2 |
UCSCi | K03H9.2, c. elegans |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | FO081582 Genomic DNA Translation: CCD72607.1 |
PIRi | S60598 |
RefSeqi | NP_495294.1, NM_062893.1 |
3D structure databases
AlphaFoldDBi | Q09578 |
SMRi | Q09578 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 6239.K03H9.2 |
Proteomic databases
PaxDbi | Q09578 |
Genome annotation databases
EnsemblMetazoai | K03H9.2.1; K03H9.2.1; WBGene00000651 |
GeneIDi | 186968 |
KEGGi | cel:CELE_K03H9.2 |
UCSCi | K03H9.2, c. elegans |
Organism-specific databases
CTDi | 186968 |
WormBasei | K03H9.2 ; CE01996 ; WBGene00000651 ; col-75 |
Phylogenomic databases
eggNOGi | KOG3544, Eukaryota |
GeneTreei | ENSGT00940000164076 |
HOGENOMi | CLU_001074_4_3_1 |
InParanoidi | Q09578 |
OMAi | RRQKRHW |
OrthoDBi | 1567071at2759 |
PhylomeDBi | Q09578 |
Miscellaneous databases
PROi | PR:Q09578 |
Gene expression databases
Bgeei | WBGene00000651, Expressed in pharyngeal muscle cell (C elegans) and 4 other tissues |
Family and domain databases
InterProi | View protein in InterPro IPR002486, Col_cuticle_N IPR008160, Collagen |
Pfami | View protein in Pfam PF01484, Col_cuticle_N, 1 hit PF01391, Collagen, 3 hits |
MobiDBi | Search... |
Entry informationi
Entry namei | COL75_CAEEL | |
Accessioni | Q09578Primary (citable) accession number: Q09578 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | November 1, 1997 |
Last sequence update: | November 1, 1997 | |
Last modified: | May 25, 2022 | |
This is version 121 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Caenorhabditis annotation project |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Caenorhabditis elegans
Caenorhabditis elegans: entries, gene names and cross-references to WormBase - SIMILARITY comments
Index of protein domains and families