Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Growth arrest-specific protein 1 homolog

Gene

phg-1

Organism
Caenorhabditis elegans
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Role in pharynx function or development.1 Publication

GO - Biological processi

  • multicellular organism development Source: UniProtKB
  • negative regulation of cell cycle G1/S phase transition Source: UniProtKB

Keywordsi

Molecular functionDevelopmental protein

Names & Taxonomyi

Protein namesi
Recommended name:
Growth arrest-specific protein 1 homolog
Alternative name(s):
Pharynx-associated gas1 homolog
Gene namesi
Name:phg-1
Synonyms:phas-1
ORF Names:F27E5.4
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome II

Organism-specific databases

WormBaseiF27E5.4 ; CE30964 ; WBGene00004017 ; phg-1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 17Sequence analysisAdd BLAST17
ChainiPRO_000002131618 – 205Growth arrest-specific protein 1 homologAdd BLAST188
PropeptideiPRO_0000021317206 – 228Removed in mature formSequence analysisAdd BLAST23

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi143N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi156N-linked (GlcNAc...) asparagineSequence analysis1
Lipidationi205GPI-anchor amidated aspartateSequence analysis1

Keywords - PTMi

Glycoprotein, GPI-anchor, Lipoprotein

Proteomic databases

EPDiQ09553
PaxDbiQ09553
PeptideAtlasiQ09553
PRIDEiQ09553

Expressioni

Tissue specificityi

Pharynx muscle cells from its early formation, in the two-fold embryo, until the adult stage.1 Publication

Developmental stagei

All developmental stages, but not dauer larva.1 Publication

Gene expression databases

BgeeiWBGene00004017

Interactioni

Protein-protein interaction databases

STRINGi6239.F27E5.4

Structurei

3D structure databases

ProteinModelPortaliQ09553
SMRiQ09553
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiENOG410K8MR Eukaryota
ENOG4110K78 LUCA
HOGENOMiHOG000016251
InParanoidiQ09553
OMAiCRKLFGG
OrthoDBiEOG091G0IIY
PhylomeDBiQ09553

Family and domain databases

InterProiView protein in InterPro
IPR016017 GDNF/GAS1
SMARTiView protein in SMART
SM00907 GDNF, 2 hits

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q09553-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRRVILPLVM TVTLCLAQEA SEACTKALTD CENDLECQNR LAPLMAACST
60 70 80 90 100
NTCQPQCRSA VLNVYQNKLG RILLRSDATC IPGRDELRTC NFLPAESTVH
110 120 130 140 150
CSLGKLACEG DLQCNSKFGV FMSECEADAA RGACTDKCKT LLNQTIETSV
160 170 180 190 200
GSVFSNCTCT ARDDQLCTNL KDNLLGVCLK NTPGVTLSPS DNSITDAPGG
210 220
NDLADSSVGH GFNILSAISV YLLTVLVF
Length:228
Mass (Da):24,345
Last modified:May 16, 2003 - v2
Checksum:i061933FB807476A1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z48582 Genomic DNA Translation: CAA88466.2
PIRiT21458
RefSeqiNP_496186.2, NM_063785.4
UniGeneiCel.20275

Genome annotation databases

EnsemblMetazoaiF27E5.4; F27E5.4; WBGene00004017
GeneIDi185024
KEGGicel:CELE_F27E5.4
UCSCiF27E5.4 c. elegans

Similar proteinsi

Entry informationi

Entry nameiGAS1_CAEEL
AccessioniPrimary (citable) accession number: Q09553
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 16, 2003
Last sequence update: May 16, 2003
Last modified: April 25, 2018
This is version 102 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Caenorhabditis elegans
    Caenorhabditis elegans: entries, gene names and cross-references to WormBase

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health